American Thoracic Society Journal news tips for March 2005 (second issue)
...al scientists indicated their data pointed up that unrecognized sleep disordered breathing might explain a portion of the association between obesity and childhood wheezing. Of the 788 youthful participants, 188 either wheezed and/or had asthma. The majority, 600, had no active wheeze or asthma. A significant ...Mayo Clinic discovers 'new pathway' against pancreatic cancer
...he Mayo Clinic researchers discovered a previously unrecognized role in pancreatic cancer for the GSK-3 Beta molecule. They determined that GSK-3 Beta is vital to pancreatic cancer cell survival and growth through its effects on a well-known gene regulator called NF Kappa B (pronounced "en-ef-kappa-bee"). The NF...Rheumatoid arthritis patients at higher risk for unrecognized heart disease and cardiac sudden death
...the general population, but they have more silent, unrecognized heart attacks and sudden cardiac deaths, according...heart attack and five times more likely to have an unrecognized heart attack. They were also less likely to have had a history of chest pain, compared to those with...Viral DNA sequence a possible trigger for breast cancer
...viral infection may be an important and previously unrecognized trigger for breast cancer. The DNA sequence in question is usually found in immune cells and helps trigger the activation and proliferation of the cells. These sequences have also been found in proteins from some other cancer-causing viruses such as...Insulin resistance intervention after stroke focus of $33 million grant
...addressing insulin resistance, a common, but often unrecognized risk factor. Insulin resistance may lead to diabetes, stroke and myocardial infarction. By some estimates, insulin resistance affects up to 50 percent of stroke patients. The drug being tested, pioglitazone, reduces insulin resistance and is currentl...Accumulated lead exposure may be an important risk factor for cataracts
...cumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men, according to... adults in the United States, may be an important, unrecognized risk factor for cataract. This research suggests that reduction of lead exposure could help decrease...Nursing homes register 41 percent drop in residents' pain
...tudies have found that complaints of pain often go unrecognized and that residents are inadequately treated or not treated at all. To address the problem, researchers at Brown Medical School teamed with Quality Partners of Rhode Island to test rapid-cycle quality improvement. Under that model, organizations ...Use of stomach acid-suppressive medications associated with increased risk of pneumonia
...ears of exposure will continue to increase and any unrecognized complications will become of greater importance." He concludes by saying: "If acid suppression causes some cases of pneumonia, it is reassuring that the risk is relatively small and that the complication in most cases is usual...Highlights summarized for movement disorders research at 56th annual meeting
...ently come under intense scrutiny for a previously unrecognized side effect. Pergolide is a dopamine agonist, a drug that acts like dopamine in the brain. Researchers from Texas presented evidence that pergolide use is associated with an increased risk for disease of the heart's valves. Echocardiograms of 46 pati...Hidden cost of depression in seniors: $9 billion in care from spouses, children
...at depression among senior citizens carries a huge unrecognized cost: many extra hours of unpaid help with everyday activities, delivered by the depressed seniors' spouses, adult children and friends. Even moderately depressed seniors, the University of Michigan study finds, require far more hours of care than t...Solvent, common drug plus hormones raise risk of reproductive failures and breast cancers
... MAA's mechanism of action as well as a previously unrecognized drug-drug interaction, said McDonnell. MAA does not bind to the estrogen receptor inside the cell, as estrogen "mimics" were long believed to have done. Instead, it acts directly upon the two aforementioned enzymes to accelerate the transcription pro...Hot flash drug may hinder effectiveness of tamoxifen
...type. The researchers identified that a previously unrecognized active metabolite, which they named endoxifen, was present in substantially higher concentrations than 4-hydroxy-tamoxifen. They observed that, after paroxetine treatment, endoxifen levels decreased, whereas levels of 4-hydroxy-tamoxifen did not. Tre...MRI shows back trouble may begin before puberty
... "We suspect there may be genetic causes, although unrecognized trauma in sports or at play could also be a cause." Lower back problems affect millions of adults. In the United Kingdom, 3 million workdays were lost in 2002 due to lower back pain, according to the National Health Service. In the United States, b...Study finds clues to brain tumors' origins
...an important advance by demonstrating a previously unrecognized connection between stem cells and pediatric brain tumor-derived cells. By viewing tumors as a type of embryonic cell gone awry, this opens up new possibilities for diagnosis and treatment," said Dr. Marianne Bronner-Fraser, a developmental biologist ...Purefecta (TM) drinking water purifier from Pall and Kinetico removes pathogens...
... present at endemic (constant baseline) levels, is unrecognized in the general population and thereby underreported. According to the U.S. National Center for Health Statistics, anywhere from $300 million to $3 billion is spent annually by U.S. hospitals on diseases caused by waterborne pathogens. The bacteria, v...Unusual fatigue may be warning symptom of heart attack in women
...est pain may be a major reason why women have more unrecognized heart attacks than men or are mistakenly diagnosed and discharged from emergency departments," McSweeney said. "Many clinicians still consider chest pain as the primary symptom of a heart attack." Other acute symptoms women reported were: shortness ...Poorer performing Philadelphia schools have more undiagnosed asthma, Jefferson study finds
... District have higher percentages of students with unrecognized symptoms of asthma, leading researchers to suggest that those students at risk receive screening for the disease. Sal Mangione, M.D., associate professor of medicine at Jefferson Medical College of Thomas Jefferson University in Philadelphia, and h...On the horizon of glucose monitoring: A review
...toring could uncover hidden glucose trends such as unrecognized glucose variations. With continuous monitoring, al... asked patients to wear this device have uncovered unrecognized glucose trends," Gabbay said. "This has allowed for better glucose control." Micropore systems use a...Infectious disease expert to speak at American Academy of Ophthalmology's annual meeting
...aused by contaminated drinking water, a previously unrecognized source of infection. According to the Centers for Disease Control, "More than 60 million people in the United States probably carry the Toxoplasma parasite, but very few have symptoms because the immune system usually keeps the parasite from causing......colleagues at Yale University reveals a previously unrecognized interaction between adenosine and IL-13 that indicates a mutual stimulation that may contribute to the nature and severity of airway inflammation and fibrosis. "The authors hypothesize that IL-13induced adenosine and adenosine-induced IL-13 productio...