UIC chemists synthesize potent anticancer compound
...han 10 years ago, laulimalide, which is chemically unrelated to Taxol, has been studied in several laboratories but is hard to come by, amounting to only one-tenth of 1 percent of a sponge's weight. It has also proven very difficult to make in the lab. "The molecule is a most challenging one in its structural...Genetics likely to be a major factor in osteoarthritis of the hip
...developing osteoarthritis of the hip compared with unrelated individuals, which suggests a strong genetic influ...round three to eightfold the rate of prevalence in unrelated people....Gene discovery shows heart failure cause, suggests treatments and screening potential
...beta blockers or ACE inhibitors." The study of 350 unrelated patients with dilated cardiomyopathy, conducted in collaboration with the Technical University of Braunschweig and the University of Utah, identified three patients who had distinct defects in the same gene. The work builds upon research first report......en patients undergo laboratory testing for various unrelated health problems. Dr. Kyle and the Mayo Clinic hematologists do not recommend that people be screened for the M-protein. Instead they suggest that physicians monitor patients diagnosed with MGUS through annual blood testing for the lifetime of the pat...Classroom management linked to lesser teen alienation from school
...dditional schooling such as a master's degree were unrelated to students' feelings about school. "Teachers can acquire the skills needed to create good classroom environments," Blum said. "But this has to be a schoolwide phenomenon in order to make a difference. We can't expect one hour a day in a well-run cla...Study finds widespread sympathetic nerve damage in Parkinson's disease
... led the study. It also shows that this damage is unrelated to treatment with the most commonly used Parkinson...hout OH. This shows that the development of OH is unrelated to treatment with levodopa, although it is possible that the levodopa may cause the blood vessel wal...Study observes no association between cell phone use and auditory tumors
...e risk of acoustic neuroma, or auditory tumor, was unrelated to the frequency and duration of cellular telephon...e monthly bill. The risk of acoustic neuroma was unrelated to cellular telephone use, said study author Joshua Muscat, Ph.D., of the American Health Foundation...Young adults dont heed warning message of heart attack or stroke in family
...ular risk. Not only was a change in family history unrelated to improved risk-factor behavior and control, but also the overall picture of observed risk-factor change was slanted opposite to the hypothesized direction, Kip reports. His team found that those young adults whose family histories indicated an incr...Firstborn: First risk for heart disease?
...ent in the reference population. Primogeniture was unrelated to age, gender and all but one of the major risk factors considered. There were no significant differences between firstborns and their sisters and brothers in terms of family history of CHD, hypertension, dyslipidemia or diabetes. But cigarette sm...HIV patients have no progression of HIV after liver transplants, Pitt study reports
...ity of Pittsburgh since 1997. Two died for reasons unrelated to complications of either their HIV or HCV....Effexor (R) XR achieved long-term remission in 67 percent of recurring depression patients
... is a structurally novel antidepressant chemically unrelated to any other available antidepressant. Effexor XR works simultaneously on both serotonin and norepinephrine, two of the chemicals that brain cells use to communicate, which are implicated in depression and anxiety. Serotonin may be involved in mood...Venlafaxine significantly effective for children and teens with generalized anxiety disorder
... is a structurally novel antidepressant chemically unrelated to any other available antidepressant. Venlafaxine inhibits noradrenaline and serotonin, two brain chemicals involved in depression. Serotonin (5-hydroxytryptamine or 5-HT) enhances mood, thus affecting, for example, impulse, appetite and feelings ...Urine test predicts Alzheimer's disease
...eimer's or whether they will progress to a form of unrelated dementia. A urine sample taken in the doctor's office may be a first point of decision in gauging the risk of developing AD. Further tests could then determine the severity of a patient's condition and course of treatment. For example, studies have ...Diabetes targets will be impractical in routine practice
...atment for existing heart disease and coincidental unrelated chronic disease, says the author. "It is difficult to see how we can realistically expect patients to comply for long with such a draconian regimen requiring so many separate drugs." He concludes: "The development of combination tablets by the pharm...Faulty gene may explain why some fall ill at high altitudes
...experiencing HAPE. All participants were Japanese, unrelated to one another, and were born and lived at elevations of less than 610 meters (2001 feet). Using the blood samples, researchers determined the DNA sequence of the eNOS gene in each participant. They found significant differences between the HAPE pat...Schizophrenia may be caused by an interaction of genes and viruses in glia cells
...othesis bridges the gap between several previously unrelated schizophrenia hypotheses, most notably the genetic, the neurodevelopmental and the virus hypotheses, thereby providing a unifying explanation for the development of schizophrenia. It is hoped that by testing this hypothesis in the laboratory, researc...UK study suggests possible link between colorectal cancer and human growth hormone therapy
...herapy for more controversial indications that are unrelated to growth hormone deficiency, particularly if such treatment is prescribed for long periods."...American Thoracic Society journal news tips for August (first issue)
...nts started to be admitted to the ICU for problems unrelated to their AIDS. These included drug overdose, trauma, and gastrointestinal bleeding. However, he decried the large number of patients not under medical supervision who show up daily in the hospital emergency room with an acute opportunistic infectio...... by day 14. The drug's effect on inflammation was unrelated to its effect on cholesterol levels, indicating the drug may work through multiple mechanisms, says Eckel. These results support those of earlier studies that found that statins appear to protect against first and recurrent heart attacks in patients ...