Jefferson scientists help explain statins' effects in Alzheimer's disease
...fic therapies," Dr. Pedrini says. "This reveals an unsuspected pathway linking statins and amyloid metabolism," says Dr. Gandy. "This may help unravel statin action in Alzheimer's as well as point the way toward novel anti-amyloid drugs." Dr. Gandy notes that the work is part of a developing anti-amyloid cocktai...Jefferson scientists uncover new evidence to help explain statins' effects in Alzheimer's disease
... therapies," Dr. Pedrini says. "This reveals an unsuspected pathway linking statins and amyloid metabolism," says Sam Gandy, M.D., Ph.D., director of the Farber Institute for Neurosciences. "This may help unravel statin action in Alzheimer's as well as point the way toward novel anti-amyloid drugs."...Unsuspected brain region involved in side effects of diabetes drugs
...and intellectual processes appears to also play an unsuspected role in the body's visceral response to dangerously low blood sugar levels, according to research at Washington University School of Medicine in St Louis. Low blood sugar, called hypoglycemia, is a common and dangerous side effect of drugs that contr...Progress and future directions for management of hepatitis C
... is projected over the next decade, as a result of unsuspected infection from contaminated blood and blood products, occupational exposure, and injection drug use prior to the advent of routine screening in the early 1990s. These chronic infections are now leading to significant increases in cirrhosis, end-stag...Early breast and ovarian cancers detected in high-risk women
...ast cancer. Of these women, two were found to have unsuspected early-stage breast cancers at the time of surgery.... also discovered. However, the finding of several unsuspected breast and ovarian cancers at the time of preventive surgery highlights the limitations of screening...MGH researchers identify angiogenesis inhibitor in gallbladder cancer
...r growth factor called TGF-beta-1 has a previously unsuspected role inregulating the growth of blood vessels associated with metastatic gallbladdercancer. They also report finding that, in animal studies of the development ofblood vessels (angiogenesis) associated with cancer, model systems in whichtumor cells ...Researchers develop better means to diagnose adrenal gland tumors
...L patients as young as 8 years of age. Deathsfrom unsuspected adrenal gland tumors have been reported in young children inthese families and it is important to make the diagnosis early so that surgicalintervention can be performed," said W. Marston Linehan, M.D., NCI's Chief of Urologic Surgery. A patient who...