American Academy of Neurology awards 2004 Potamkin Prize to two scientists
...r it was possible to develop an effective and safe vaccine against Alzheimer's disease. Nitsch's work in expe...e hope that science can find an effective and safe vaccine against Alzheimer's disease. His research produced groundbreaking evidence linking beta-amyloid depo...Other highlights in the April 21 JNCI
... used regularly by those with access to it. An HPV vaccine is currently being tested in clinical trials and m...lic soon. To estimate the effectiveness of the HPV vaccine in areas such as the United States where there are established screening programs, Sue J. Goldie, M....Second NIAID SARS vaccine candidate helps mice fend off SARS
An experimental vaccine based on a critical piece of the SARS virus protec... NIAID in recent weeks describing a promising SARS vaccine candidate. "We now have two candidate vaccines, based on two distinct technologies, shown to be eff...SSX, a new family of cancer vaccine targets
...p late in the disease progression, we think that a vaccine that stimulates and amplifies this naturally-occur...archers in New York. "We believe that for a cancer vaccine to be effective, you really need to be able to induce, and monitor, the activation of all three comp...How cancer neutralizes T cell attack
...d suggests new weapons for inclusion in the cancer vaccine arsenal. In order to understand how tumors escape ...both the frequency and the functional potential of vaccine induced specific CD8 T cell responses not only in peripheral blood but also at the tumor sites. The ...HIV-positive U.S. military personnel accidentally vaccinated against smallpox
...IV-positive, only three were known to be "primary" vaccine recipients, or had never been vaccinated before. T...ld become ill perhaps even lethally ill from the vaccine itself. "In the absence of any cases of smallpox in the world, vaccination programs should take care...Avian influenza outbreaks create concern about human infection Mayo Clinic researchers warn
...rs can be protected. Dr. Baddour also notes that a vaccine against this virus needs to be developed. Since mid-December 2003, Cambodia, China, Indonesia, Japan, Laos, South Korea, Thailand and Vietnam have reported outbreaks of the avian influenza strain H5N1. Vietnam and Thailand have reported influenza H5N...American Thoracic Society Journal news tips for April 2004 (second issue)
...harge orders that would call for current influenza vaccine and pneumococcal pneumonia vaccine, plus a smoking cessation program if needed, for all recovered pneumonia patients. The study and editorial appear in the second issue for April 2004 of the American Thoracic Society's peer-reviewed American Journal...Duke scientists overcome immune resistance in dendritic cell vaccines for cancer
...from the cancer antigen, said Yang. When the viral vaccine presents the tumor antigen to fighter T-cells (via the patient's dendritic cells), it is also presenting its own PAMPs. The dual signaling in actuality there are three signals from dendritic cells provide the needed stimulus to energize T cells int...NIAID vaccine protects against SARS virus infection in mice
An experimental vaccine prevents the SARS virus from replicating in labora...l Institutes of Health, developed the vaccine. The vaccine was tested in a recently-described mouse model of SARS infection with other NIAID investigators. ...Monkey virus may hold clue for development of common blood cancer
...her SV40, which contaminated some batches of polio vaccine in the 1950s and 60s, could cause human cancer, especially after the virus was discovered in human tumors. Given that, the M. D. Anderson researchers looked to see if either DNA from the virus or associated antigens or antibodies could be found in no...Mouse model mimics real-world plague infection
An experimental plague vaccine proved 100 percent effective when tested in a new ... Diseases (USAMRIID), where the recombinant plague vaccine tested in the model was made. "Replicating the natural transmission of plague from flea to host ...Rochester, BCM test bird-flu vaccine in humans
...beginning the first test in the United States of a vaccine designed to protect people against one form of bir...n outbreak of the virus occur in humans. While the vaccine under study is not designed to protect against the precise bird-flu virus causing the current outbre...Tuberculosis strains stay close to home, say Stanford researchers
...trated in HIV. "This has profound implications for vaccine development," he said. "We may ultimately need to develop different vaccines for different parts of the world. It's a completely open question, but we can start to answer it now."...Making the case for a dental caries vaccine
... ill, or institutionalized. For decades, a dental vaccine has been the topic of mucosal immunology and infec... case for the scientific and moral imperative of a vaccine to prevent caries in disadvantaged populations, in the United States and other industrialized countr...Mouse antibodies thwart SARS virus
...blic health experts have been anxiously awaiting a vaccine for this potentially fatal respiratory ailment. Kn...p lessen the time it takes to develop an effective vaccine or antiviral drugs for SARS. In collaboration with colleagues at the Centers for Disease Control and...Effectiveness of safer smallpox vaccine demonstrated against monkeypox
A mild, experimental smallpox vaccine known as modified vaccinia Ankara (MVA) is nearly as effective as the standard smallpox vaccine in protecting monkeys against monkeypox, a study by researchers of the National Institute of Allergy...Jefferson Alzheimer's vaccine shows promise in animal model
A new vaccine for Alzheimer's disease created by researchers at ... Dr. Gandy and his colleagues tested the vaccine in four aged rhesus monkeys. Two monkeys were given beta-amyloid; the other two were given a placebo...New animal model for Alzheimer vaccine
... vaccine. This may enable scientists to study the vaccine in an animal model of Alzheimer's that is very sim...s side effects that halted an earlier study of the vaccine in people, according to the Alzheimer's Association. "The animal model described in this study expan...Majority of authors retract 1998 Lancet paper-Lancet editor points to implications
...s paper no causal link was established between MMR vaccine and autism as the data were insufficient. However,...s of research misconduct. Mechanisms to establish vaccine safety should be strengthened by securing and constantly adding to a reliable evidence base early on...