Tag: "vascular" at medical news

Joslin announces first international affiliate in Bahrain

... have polycystic ovary syndrome have a history of vascular disease Diabetes-related Costs Because it is a chronic disease, diabetes management can have an emotional and economic toll on people with diabetes, their families and their health systems. Emotional Diabetes is a complex disease and can lead to a...

High blood-sugar levels indicate greater chance of death for critically ill patients

...ink that tight glucose control results in improved vascular function and lower risk of infection." Dr. Krinsley, who is an associate clinical professor of medicine at the Columbia University College of Physicians and Surgeons, reviewed data for 1,826 patients whose glucose values were obtained durin...

Beers criteria for medications to avoid in the elderly updated

...ients with disease such as diabetes and peripheral vascular disease. "What we didn't do, and I hope someone does, is we didn't say, 'Here is a list of the safest drugs,'" Dr. Fick said. She knows that the new criteria will cause some controversy but stressed that it's not intended as an absolute or to tell p...

Roche files marketing application for Avastin with European health authorities

...ti-cancer agent with proven efficacy in inhibiting vascular endothelial growth factor (VEGF), which suppresses tumour growth and the spread of cancer from one part of the body to another (metastasis). As this mechanism of action could prove relevant in a number of solid tumours we are presently investigating...

JCI Table of Contents

...in immunity. TITLE: Proinflammatory functions of vascular endothelial growth factor in alloimmunity AUTHOR CONTACT: David M. Briscoe Children's Hospital, Boston, Massachusetts, USA Phone: 617-355-6129 Fax: 617-232-4315 E-mail: david.briscoe@tch.harvard.edu View the PDF of this article at: https://www....

Its never too late to start exercising and losing weight , Joslin study shows

...ral markers of blood coagulation, inflammation and vascular activity, which are usually altered in this population, putting them at higher risk for developing coronary artery disease. Significance of the findings "The important finding of this study is that a weight loss as low as 7 percent ...

Northwestern Memorial enrolling participants in two trials on new drug to fight deadly cancer

...l advancements in such areas as cardiothoracic and vascular care, gastroenterology, neurology and neurosurgery, oncology, organ and bone marrow transplantation, and women's health. Northwestern Memorial was ranked as the nation's 5th best hospital by the 2002 Consumer Checkbook survey of the nation's physici...

Experimental drugs show promise in halting brain tumors

...lly, ZD6474 blocked activation of the receptor for vascular endothelial growth factor (VEGF), the protein that malignant cells secrete in order to grow and maintain their blood vessels. When VEGF receptor cannot activate itself, the tumor's blood supply is diminished and the tumor shrinks and slows its spread...

Bayer and Onyx announce new data on dual mechanism of action of BAY 43-9006

... of tumor cells. VEGFR2 is a main receptor of the vascular endothelial growth factor (VEGF), which plays a key role in angiogenesis. Additionally, updated Phase II clinical data was presented at the meeting, evaluating BAY 43-9006 as a potential treatment of advanced renal cell carcinoma (RCC, or kidney can...

Leading the way in novel anti-cancer research

... receptor (EGFR) tyrosine kinase inhibitor and the vascular targeting agent ZD6126. New frontiers in cancer ...ch presented at the meeting shows that combining a vascular targeting agent with an EGFR tyrosine kinase inhibitor may result in greater anti-tumor activity tha...

Other highlights in the November 19 issue of JNCI

... beta4 was associated with increased expression of vascular endothelial growth factor, which is involved in tumor angiogenesis. Contact: Bob Kuska, National Institute of Dental and Craniofacial Research, 301-594-7560, kuskar@nidcr.nih.gov . Moderate Drinking Associated with Higher Hormone Levels Postmenopa...

New evidence links inflammation to venous disease

... recently, DVT was thought to be solely a blood or vascular disorder. Now, scientists from the University of M...," says Thomas W. Wakefield, M.D., a scientist and vascular surgeon in the U-M's Cardiovascular Center. "When a clot forms deep inside the leg, these signs are ...

JCI Table of Contents, November 14, 2003

...ype plasminogen activator (tPA): the regulation of vascular tone and the permeability of the blood-brain barrier (BBB). The authors demonstrate that an increase in perivascular tPA, as a consequence of cerebral ischemia, results in an opening of the BBB. Blockade of LRP, with anti-LRP antibodies or by other m...

UCLA researchers to test experimental pill

...igned to block the cellular receptors for VEGF, or vascular endothelial growth factor, which signals blood vessels to grow. "It's a little like satellite television," Hecht said. "The signal, VEGF, is picked up by the receptor, which is like a satellite dish. If you're a blood vessel, this signal tells you t...

Multi-hospital angioplasty improvement effort reduces deaths and complications

...mergency surgery," says Moscucci. Impact of other vascular disease on angioplasty outcomes : Angioplasty open...ee and his colleagues showed that patients who had vascular disease in areas outside the heart were at a significantly higher risk of dying in the hospital and ...

Bone marrow stem cells build new circulation to lungs

...sity of Toronto and St. Michaels Hospital, removed vascular progenitor cells from rats bone marrow. The cells were cultured for five days, then injected into the pulmonary circulation of rats with PAH. A second group of rats with PAH received skin fibroblasts (cells), while a third group, which did not have...

Exercise has a more powerful impact on the brain than previously thought

...rtant implications for helping people recover from vascular injuries and trauma. In general, all of this latest research on exercise and the brain seems to suggest that some minimum level of physical activity is important for keeping the brain functioning at normal levels. "Exercise affects more than the mus...

Study of deadliest form of stroke demostrates much lower mortality rates at high caseload hospitals

...ned" out. Other origins of hemorrhagic stroke are vascular malformations, high blood pressure that leads to the rupture of a tiny artery or vein, and drugs that create a dysfunction of the clotting system. Blood from the burst aneurysm can severely injure the brain, making SAH a catastrophic event that requi...

Systolic better than diastolic or pulse blood pressure as indicator of mortality risk

...nhealthy and can lead to heart disease, stroke and vascular diseases of the legs. Diastolic pressure, the lower number, measures the pressure as the heart relaxes to fill with blood. A diastolic pressure greater than 80 mm Hg is also considered unhealthy. Pulse pressure is the difference between the diastolic...

Wild blueberries may help protect arteries, reduce risks from cardiovascular disease

...r of cells known as the endothelium. "Increasing vascular resistance may lead to an elevation of blood pressure which may in turn damage the delicate endothelial layer," says Klimis-Zacas. "This layer is affected by many things in the blood. By removing the endothelium, we are left with the smooth muscle la...

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