In lab studies, blocking expression of gene reduces invasion of deadly brain tumor cells
...ll migration both in glioma cells and in adjacent vascular cells circumstances that are necessary for local tumor invasiveness. "Antisense oligos to laminin-8 chains significantly inhibited invasion of two different glioma cell lines in vitro," said Dr. Ljubimova. "If these laboratory studies can be transla...Aortic aneurysm death risk hinges on choice of surgeon, study finds
... specializes in surgery on blood vessels, called a vascular surgeon. If you can't find one, at least try to go... R. Upchurch, Jr., M.D., an assistant professor of vascular surgery at the U-M Medical School. "And the experience of the individual surgeon may count even more...UCSF vascular surgeons develop new technique to repair aortic arch aneurysm
A novel treatment developed by UCSF vascular surgeons has been used in a first-of-its-kind oper...d flow to the brain," said Darren Schneider, MD, a vascular surgeon at UCSF Medical Center and lead author of a paper which appears in the October issue of the ...Study confirms benefits of hemispherectomy surgery
...flammation of the brain, and those with congenital vascular injuries benefit the most from hemispherectomy. Si...smussen's patients and 81 percent of patients with vascular injuries are now seizure-free. Although children with disorders of brain development (dysplasias) h...World experts present respiratory and critical care research at CHEST 2003, intl scientific assembly
...ediatric pulmonology, disaster medicine, pulmonary vascular disease, lung cancer, and critical care. "CHEST 2003 will gather leaders in the field of chest medicine who will provide a thorough examination of the most current scientific developments in a variety of subspecialties," said Curtis N. Sessler, MD, F...A dangerous duo: Heart disease and diabetes
...ed all the known pathways of hyperglycemia-induced vascular damage, suggesting that PARP inhibitors might have unique clinical efficacy in preventing the development and progression of diabetic complications of the cardiovascular system. In an accompanying commentary, Jane Reusch from the University of Color...Novel technology to monitor 'hidden depths' of silent killer
...vessels which may enable us to better evaluate the vascular effects of lipid-lowering therapy, and in clinical practice the use of MRI could facilitate early diagnosis and treatment," stated Dr. Baocheng Chu of the University of Washington School of Medicine, Seattle and investigator for ORION. He continued,...UCSD-TCAG collaboration to focus on transformation of genome-based knowledge into health benefits
...blood pressure, blood flow, release of adrenaline, vascular reactivity and various tests measuring patient responses to drugs and drug doses. The polymorphism data from the sequenced DNA will then be analyzed in conjunction with the phenotypic information using information technology-enabled approaches that ...High blood pressure is a factor in some 'senior moments'
...ssels to compensate for the higher pressure. This vascular remodeling, said Jennings, probably explains the b...blood pressure medicines that specifically address vascular changes -- such as angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (...Uninsured face higher death risk from aorta problems
...t R. Upchurch Jr., M.D., an assistant professor of vascular surgery at the U-M Medical School. "In other words, access is linked directly to death." Upchurch led the study with former U-M medical student Leslie K. Boxer, M.D., now at Cornell University, using data from the National Inpatient Sample database c...Joslin and Beth Israel Deaconess Medical Center sign new joint venture clinical agreement
...ney and pancreas dysfunction, obesity, neuropathy, vascular complications and high-risk pregnancy). The agreem...oslin and BIDMC will continue existing programs in vascular surgery for diabetes complications; clinical endocrinology; nephrology; mental health; podiatry serv...Hospital care quality differs markedly by state: annual HealthGrades study
...hGrades.com. They cover cardiac care, orthopedics, vascular surgery, neurosciences and pulmonary medicine. New categories added this year include atrial fibrillation, gastrointestinal bleed, sepsis, prostatectomy, cholecystectomy and bowel obstruction. A five-star rating in a given category reflects performa...Mt. Sinai researchers report that aspirin reduces risk of first heart attack by one-third
...uces the combined risk of heart attack, stroke and vascular death by 15 percent. Charles H. Hennekens, M.D.,... of thousands of first heart attacks and important vascular events each year in the U.S." The aspirin component of Dr. Hennekens trial, the PHS, was terminated ...Evaluation needed to gauge silent threat lurking within stroke patients
...mini stroke,") and ischemic stroke all result from vascular disease, where blood flow is restricted to either ...ur percent to 45 percent of deaths were related to vascular disease other than stroke. In examining stroke subtypes, people with obvious large-vessel strokes ...Tip sheet for August 26 Neurology and more news
...und beneficial in treating congitive impairment in vascular dementia (VaD) patients: In a double-blind, placebo-controlled trial of two doses of donepezil, a cholinesterase inhibitor, the drug improved the cognitive function of VaD patients, with the greatest improvement shown among those taking the lower do...Smoking causes half the tuberculosis deaths in Indian men
...se they smoked. Most adult deaths in India involve vascular disease, pulmonary tuberculosis, or other respirat...lved respiratory disease (chiefly tuberculosis) or vascular disease (chiefly heart attack). Smoking also caused similar excesses of respiratory and vascular mor...Infections linked to mental decline in elderly
...ng Alzheimer's, which is increasingly considered a vascular disease, Strandberg says. They found that 79 patients (20.6 percent) had no antibodies to either; 182 (47.5 percent) had antibodies to one of the bacterium; and 122 (31.9 percent) had been infected by both. However, the researchers found no associat...SFVAMC researchers distinguish dementias using brain imaging
...mer's disease, but we do have options for treating vascular disease. So, being able to determine that there is a vascular component to a patient's dementia would make a big difference in planning for treatment," said Norbe...Newer vitamin D formulation appears to help dialysis patients live longer
...roidism overactivity of the parathyroid gland on vascular disease. Part of an imbalance in bone and mineral metabolism that results from kidney failure, hyperparathyroidism is usually treated with intravenous vitamin D therapy. However, treatment with vitamin D may exacerbate cardiovascular disease. Pa...Cholesterol drug helps heart failure patients without high cholesterol
...ays senior author James K. Liao, M.D., director of vascular medicine research at Brigham & Women's Hospital and associate professor of medicine at Harvard Medical School, Boston, Mass. "This was a surprising finding in that the benefits occur after only 14 weeks of treatment and with a very low dose of the d...