Study Shows Gum Disease Increases Risk Of Future Heart Disease
...co said. "Oral bacteria enter the bloodstream via small ulcers in the gum tissue. These bacteria causes platelets to aggregate and form clumps, or thrombi. These clumps accumulate on damaged tissue, such as lesions in the blood vessel or a heart-valve replacement, which represents a damaged are...Antimicrobial "Bug Spray" Found In Human Lung Cells
...ys thought that the lungs only attacked infections via the classical immune system--B cells, T cells and other immune cells," says Pete Pedersen, Ph.D., Hopkins professor of biological chemistry. "But lung cells apparently have their own first-line defense mechanism--they shoot out one or more peptides...Targon And Duke Cancer Center Sign $3.75 Million Agreement To Produce Advanced Anti-Cancer Drugs
...gents/technologies that warrant continued research via clinical studies. The remaining portion of the funds will support pre-clinicaland clinical trials of new compounds developed at Duke, or other institutions, which are currently identified as Investigational New Drug (IND) candidates. The U.S....Radio Frequencies Used To Kill Inoperable Liver Tumors At Penn's Cancer Center
... To get at those formerly inaccessible tumors via radio frequency ablation, surgeons use ultrasound as a visual roadmap to guide a needle-sized probe directly into the center of the cancerous tumor. Once inside the tumor, the tip of the probe is carefully opened to permit heat-delivering wire extens...Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis
...e formation. Nerve cells communicate via specialized cell-cell contacts, the so-called synapses. Upon stimulation of the presynaptic cell, neurotransmitter is released from its nerve endings. The released transmitter molecules diffuse to the adjacent nerve cell and...Advisory: Nasal Spray Influenza Vaccine
...le because it's administeredthrough a natural root via nasal passages. Maassab said that the vaccine isa...atNews & Information Services at (734) 647-4411 or via E-mail at amelynr@umich.edu...New Radiation Procedure Targets Liver Malignancies
... with chemotherapy delivered directly to the tumor via the hepatic artery. As a result of that research, they have developed a detailed formula for estimating the risk of radiation-induced liver disease for individual patients, based on the volume of normal liver tissue that is irradiated along with can...... there is an immediate down-regulation of cortisol via thehypothalamic-pituitary-adrenal (HPA) axis--negative feedback loop--whichresults in a normal plasma concentration of the stress hormone cortisol. For patients with a depression, and healthy individuals with a geneticpre-disposition for depression, ...One-Time Needles Don't Reduce HIV Among Addicts, Study Shows
...avenously, methods for preventing HIV transmission via needlereuse have received considerable attention. ...dy examines one proposal, the introduction of DTRs via a one-for-oneexchange for regular syringes. In that case, while both DTR and regular syringeswould b...Paying Attention To High Blood Pressure Programs A Good Investment In Reducing Stroke Risk
...ressive program featured announcements transmitted via speakers attachedto each household telephone. The announcements recruited participants to bloodpressure screenings and adult classes. Individuals could turn the speaker off.More than 80 percent of people between the ages of 40 to 69 years were scree...Researchers Begin Drug Trial In Hope Of Finding New Ways To Treat Acute Kidney Failure
...tically receive news releases from UT Southwestern via e-mail, send amessage to UTSWNEWS-REQUEST@listserv.swmed.edu. Leave the subject line blank and in thetext box, type SUB UTSWNEWS...Tiny Pellets Could Deliver Alzheimer's Drugs
...otential of being injected directly into the brain via a large-bore needle or catheter. Belcheva has modified the NGF molecule chemically so that it will bind with the polymer. The microspheres have not yet been tested in rat brains. Saltzman speculates that this drug delivery system might well offer a...Magnetic Hearing Aid Could Open New "Window" For Hearing Impaired
... touse an electromagnet to stimulate the inner ear via the round window. A major feature of Spindel's approach is that the device doesn't obstruct thenormal hearing process. "Leaving the middle ear system intact and establishinga second independent input pathway to the inner ear opens the possibility fo...DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice
...nd store. The mice were immunized with human DNA via a novel delivery system called a genegun, in which microscopic gold particles were coated with the human DNA andinjected into the mice's skin using a burst of helium gas. Once inside the skincells, the DNA triggered an immune response. In the study,...Mechanism By Which Estradiol Protects Women From Heart Disease Suggested By Emory Team
...PO protein oxidizes LDL and clears theoxidized LDL via the liver. Estradiol may further act as a prooxidant in the oxidation of LDL by MPO."Based on its ability to inhibit copper-mediated oxidation of LDL, it has been suggested that E2 (estradiol) might act as an antioxidant and prevent theoxidation of......hin the respiratory tract. Administering zanamivir via an inhaler ensures that the drug is delivereddirectly to the surface of the respiratory tract - the only site of influenzavirus infection in humans. It also means that high levels of the drug reach thesite of virus replication. Zanamivir has been de...Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
...nters the same HLA molecules in adult life via a sibling-donated kidney, this state of induced immune tolerance prevents rejection of the mismatched kidney. "Finding ways to induce immune tolerance to foreign tissue is the ‘Holy Grail’ of transplantation resear......nuscripts will be submitted by the authorsdirectly via the World Wide Web; will be available to peer reviewers on theWorld Wide Web; and, once accepted and copyedited, will be available to readerson the World Wide Web. The journal invites manuscripts from all areas of thepharmaceutical sciences: Analyt...MIT Microchip Releases Chemicals On Demand
...rtain hormones every 90 minutesfor weeks at a time via a catheter inserted through the skin. Those hormonescould potentially be incorporated into a chip that is implanted under the skinand programmed to release the contents of specific reservoirs at specific times. "The applications, I think, are unlimit...Viagra Prescribing Will Be Based On Financial Rather Than Clinical Reasoning
...hisholm, Chairman General Practitioners Committee, via the BMA Press Office pressoffice@bma.org.uk...