Hopkins Researchers Develop Under-The-Skin Implant For Pain Treatment
...s in the brain and eliminates narcotic craving and withdrawal symptoms. "In essence, these people become addicted to the clinic. They cannot travel or seek employment that would require them to be away from the clinic," says Deborah J. Rhodes, M.D., Robert Wood Johnson Fellow at Johns Hopkins and participant i...Study Demonstrates Safety & Effectiveness Of Asthma Drug
...relief of asthma symptoms. Duringa final four-week withdrawal period, all patients received only as-neededalbuterol. The study showed that even though the average use of albuterol was fivetimes higher in the regular use group than in the as-needed group, therewere no significant differences between the two gro...Drug Is First In Decade To Show Promise Treating Generalized Anxiety Disorder
... cause physiologicdependence leading to subsequent withdrawal distress, Davidson said. Moreover,they don't help treat the depression that is found in 30 percent to 50 percentof GAD patients. Buspirone doesn't carry the risk of dependence, but many peopledon't respond to its effects. Davidson speculates...Successful Cancer Therapy May Doom Later Treatments To Failure
...in the shrunken hormone-dependent tumors. In fact, withdrawal oftestosterone resulted in a reduction of pore size from 200 nanometers (nm) toless than 7 nm within 48 hours in a testosterone-dependent tumor. "That tells you that you just can't make a drug and expect it to work on alltumors," says Jain. Sue Hobb...UF Psychiatrists Use Antidepressants To Treat Smoking Addiction
...icotine patch, which helps smokers cope with acute withdrawal symptoms. "Social prohibitions, the stigma... using nicotine replacement therapy to treat acute withdrawal symptoms and antidepressants to combat the longer-lasting brain changes. Smoking releases a ......rcedalcohol consumption and, subsequently, alcohol withdrawal conditions, theyexhibit enhanced anxiogenic reacti... mice showedless anxiogenic behavior under alcohol withdrawal then wild-type mice. Thus byeliminating CRHR1 functions, anxiogenic behavior can be manipulated and ...Epilepsy Drug Found To Stop Cocaine's Effects In Animals
...beaddictive in themselves, or create tolerance and withdrawal symptoms." GVG's anti-cocaine effects, however, have been tested more extensivelyin animals than any of the previously reported drugs. The BNL-led team used atotal of ten techniques, including state-of-the-art medical imaging and behaviorst...Statistician Keeps Health Researchers Ahead Of The Curve
...swanted to see whether a new medication would ease withdrawal pain. Researchersstudying men's health needed to know how HIV infection affects immune cellcounts over a period of years. To help make sense of the raw data they collected, scientists in each of thesestudies called in Colin Wu, a biostatistics expert...Breakthrough? Study Finds Dopamine Cannot Be Source Of Pleasure In Brain
...elp identify less toxic substances that could ease withdrawal andmake it more successful. "Because nobody ever had a way of making these kinds of measurements, wethink this is really a big jump ahead," he said. "Often it is new technologythat in fact drives new findings in science and medicine." ...Repeated Exposure To Cocaine Alters Brain Structure
...,well outlasting the acute effects of the drug and withdrawal from it. "We propose that the increased synaptic connectivity resulting from repeatedexposure to cocaine and amphetamines produces a hypersensitivity, or neuralsensitization, in these areas of the brain, stimulating animals and people toconstantly wo...Anti-Depressant Drug Shows Promise As Weight-Loss Treatment
...Gadde, lead investigator of the study. "Since the withdrawal of fenfluramine and dexfenfluramine, there has been agreat need for effective medications," Gadde said. "More than 55 percent ofAmericans are considered overweight or obese, and obesity carries with it atremendous risk of high blood pressure, coronar......uids, electrolyte replacement and, where possible, withdrawal ofdrugs that adversely affect the colon's motility, such as narcotic painrelievers.) They were randomly assigned to treatment with either intravenousneostigmine or saline solution as a placebo (inactive substance). A physicianwho was unaware ...Early warning signs of violence often overlooked, study finds
...g and teasing and be more aware of signs such as a withdrawal fromfriends and a regular lack of eye contact with peers and adults -- all of whichexperts believe preceded recent school violence in Colorado, Arkansas, Kentuckyand elsewhere. These indicators of emotional distress are harder to detect andeasier to ...Alcohol researchers prove brief intervention successful in older problem drinkers
...s who remained eligible after exclusion foralcohol withdrawal symptoms, past alcohol treatment, cognitive impairment, orsuicidal ideation were randomized to either an intervention or control group. Patients in the intervention group received a general health booklet and werescheduled to see their personal physi......thers' negative emotions and stress-related social withdrawal on thefamily, and suggests other risk factors that seem to hamper parents' knowledgeabout their children's activities, including the indirect effect of a sibling onoverall awareness. "We found that fathers' work demands were related to lo...SFU author examines mothers and illicit drug use
...isregards the fact that neonatal syndrome (NAS) -- withdrawal symptomsranging from flu-like symptoms and tremors to dehydration, and possibly,death -- is not a predictable outcome in babies born to drug addicted mothers." Boyd points to European studies that show "drug addicted mothers are just aslikely to hav...Conference convenes on ibogaine, a controversial drug to treat heroin addiction
...ined relief from theiraddiction, without suffering withdrawal symptoms, by using ibogaine. Ibogaine isinteresting because it appears to have a novel mechanism of action. Thisconference will explore ibogaine's possible mechanism of action and focus on theclinical, cultural and political issues concerning its use...Use it or lose it applies to nervous system, scientists find
...fibers skulks away if ignored.This may explain why withdrawal of neuromuscular blocking agents sometimes isfatal to patients who have been on respirators. And it supports the idea thatlearning involves rapid molecular changes at cellular junctions in the brain. "Our study shows that activity in the nervous syst...Duke geneticists unraveling the tangled web of autism
...y talk later than normal, while others have severe withdrawal with self-destructive patterns of repetitive head banging and difficulty sleeping. In the past, many parents endured frustration and shame when told that their withdrawn, silent, autistic child is a product of their own poor parenting. But the Duke r......ng." Most current smoking cessation methods reduce withdrawal symptoms by replacing nicotine via patches, gum, inhalers or vaporizers. The prescription drug Zyban is an anti-depressant approved for use as a stop-smoking aid. In a study with 11 smokers, Sellers has demonstrated that the psoriasis drug methoxsale...