Nevirapine plus zidovudine to prevent perinatal HIV in Thailand
Researchers from the Perinatal HIV Transmission Trial group (PHPT), an international program in collaboration with Thailand, France and the US, show that a simple two-drug regimen can reduce the risk of mother to child HIV transmission to below 2%, a result similar to those achieved using HAART during pregnancy. In the absence of any intervention, 35% of the infants born to HIV-infected mothers...Study evaluates Abacavir, Lamivudine and Efavirenz versus Zidovudine, Lamivudine and Efavirenz
Chicago, Sept. 14, 2003 A treatment regimen of Ziagen (abacavir sulfate) (ABC), Epivir (lamivudine) (3TC) and efavirenz (EFV) has been shown to be non-inferior to the often prescribed regimen of Retrovir (zidovudine) (ZDV) and 3TC and EFV in a large Phase III clinical trial comparing virologic response in treatment-nave HIV+ adults. The 48-week data from the trial (CNA30024) were reported here....Children exposed to zidovudine (ZDV, AZT) in utero and as newborns and who.escaped acquiring HIV from their infected mothers show no cancers or other.adverse health effects up through preschool age, according to a new study from.the National Institutes of Health (NIH). It is the first report to assess the.late effects of AZT exposure in healthy HIV-uninfected children born to mothers.who took...