A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
PHILADELPHIA The same signal responsible for promoting the type of immune responses that cause asthma and allergy can also limit the type of inflammation associated with debilitating diseases like inflammatory bowel disease, arthritis and multiple sclerosis, according to researchers from the University of Pennsylvania School of Veterinary Medicine. The researchers discovered how IL-25, a signal...Stanford study reveals protein's Jekyll-and-Hyde role in cancer growth
STANFORD, Calif. - Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality. Though menin is well-known for its ability to suppress endocrine tumors, researchers at Stanford University School of Medicine have discovered that it is also a key player in the development...