Study details catastrophic impact of nuclear attack on US cities
...epared well in advance." One intervention is to mount a public awareness campaign to teach civilians what to do in the event of a nuclear attack. Since radioactive plumes move downwind, a person can look up at the trees to see which way the wind is blowing and then flee perpendicular to the wind. Becaus...US Military Cancer Institute partners on cancer trial
...or studies to be critical for the immune system to mount an effective anti-tumor response. ...'Erectile dysfunction' drugs heighten natural anti-cancer activity
... them hidden from white blood cells (T-cells) that mount attacks on tumors. These NO-producing cells, a.k.a. myeloid-derived suppressor cells (MDSCs), normally use nitric oxide to help bring the immune system back down to surveillance levels after an "attack mode" response to foreign material. The imp...Unless we tackle AIDS, many countries will not meet the Millennium Development Goals
...malaria People infected with HIV are less able to mount an immune response if they become co-infected with malaria or TB. "Failure to halt and reverse the AIDS epidemic will continue to jeopardize progress toward achieving a wide range of the MDGs," conclude Hecht and colleagues. "From now until ...Policy makers, networking agencies told to get their act together for nanoscience
...o countries such as the US and Japan unless it can mount a coherent approach. Instead of the usual self-congratulatory rhetoric and gushing about the blue-sky potential of nanotechnology, participants were treated to several topics by experts to deconstruct the myths, the challenges, and the future of ...Wide racial disparities found in coronary artery disease deaths
...atients, Thomas said, the medical community should mount concerted efforts to attract more blacks into participating in clinical trials. "There has been a history in the black community of mistrust of the health care system, which has often been seen as using blacks in medical experiments," Thomas said. ...Link between autism and abnormal blood-vessel function and oxidative stress
...xcessive free radicals accumulate, these molecules mount an attack against the cell in search of chemical stability. "During oxidative stress, it is as if the free radicals have only one leg," explains Pratico. "They are searching for the second leg in order to keep from falling. Unfortunately, the abil...Zebrafish show advantages in assessing human cancer cell-induced angiogenesis in vivo
... tumor mass formation which was confirmed by whole mount immunostaining and histology; activated zebrafish endothelial cells were embedded in the cancer cell masses....Mayo Clinic links allergies to Parkinson's disease
...en the diseases. "People with allergic rhinitis mount an immune response with their allergies, so they may be more likely to mount an immune response in the brain as well, which would produce inflammation," Dr. Bower says. "The inf...New hope in cancer vaccines emerges as novel therapies are developed and tested
...n. "The donor has a healthy immune system and can mount a reaction against the antigen," says Neelapu. Those primed stem cells will then be given back to the patient, "improving the chance of a graf-versus-myeloma effect," he says. Also being tested at M. D. Anderson are two different idiotype vaccines ...Baylor Institute for Immunology research receives $3 million grant to create cancer vaccines
...ique for making melanoma vaccines that are able to mount an immune response against the cancer. It is a very exciting time to be involved in cancer vaccine research at Baylor." ...Radiation-killed bacteria vaccine induces broad immune response in mice
...n characteristics that prompt the immune system to mount a full-fledged defense," says Dr. Datta, the study's lead author. "In this respect, irradiated pathogens more closely mimic the body's response to a live, attenuated vaccine." Finally, the scientists found that mice could be protected by vaccin...Novel gene therapy may lead to cure in hemophilia A patients
...of patients see the FVIII as a foreign protein and mount antibodies to destroy it, rendering the FVIII treatment useless. Newer FVIII treatment products that bypass this attack can run into $10,000 or $100,000 per treatment episode and costs for a patient may exceed $1 million annually. So far attempts ...EGF receptor activation prevents microbes from going more than skin deep
...er against infection but skin cells themselves can mount an immune response to kill invading microbes by producing antimicrobial polypeptides (AMPs). As overt infection in the skin is a rare event, researchers have theorized that AMPs must not only help fight infection, but play a role in preventing infect...Intimate partner violence the hidden burden is common
... his coauthors conclude: The time has arrived to mount and evaluate major interventions in day-to-day medical practice, as they and others have proposed. These efforts could employ universal routine questioning coupled with links to institutional and community services, so the practitioner's fear of op...JCI table of contents: May 4, 2006
...ted that mice deficient in H1Rs were still able to mount a Th2 immune response. In an effort to clarify this discrepancy, Paul Bryce and colleagues from Northwestern University, Chicago, examined H1R-/- mice with asthma and in their study appearing online on May 4 in advance of print publication in the Jun...Halting histamine action means hallelujah for hay fever sufferers
...ted that mice deficient in H1Rs were still able to mount a Th2 immune response. In an effort to clarify this discrepancy, Paul Bryce and colleagues from Northwestern University, Chicago, examined H1R-/- mice with asthma and in their study appearing online on May 4 in advance of print publication in the Jun...JCI table of contents: May 1, 2006
...ion in which they lack C4 or C2, are still able to mount a substantial immune response. They found that in these individuals, C2 is bypassed and lectin binding to sugars on the pathogen instead engages the alternative pathway and formation of another C3-cleaving enzyme, C3bBb. This 'bypass' pathway may be ...A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
...archers saw a dramatic reduction in the ability to mount a type 2 response that eradicates the parasites. Furthermore, in the absence of IL-25, mice developed a destructive inflammatory response similar to that observed in models of inflammatory bowel disease. These results also support the notion that t...Cedars-Sinai researchers discover treatment for deadly brain tumors and infections
...he organ has immune privilege and therefore cannot mount a defense against cancer or other infectious disea...athogens or tumors; however, it is not possible to mount an effective immune response from the brain itself because it lacks antigen presenting cells. In the...