Shape-altering genes linked to ovarian cancer
...tive to levels of the female hormones estrogen and progesterone produced in the reproductive organs, Naora speculates that abnormal changes in levels of these hormones could explain how the HOX genes come to be turned on in ovarian tissue. Indeed, most of the known risk factors for ovarian cancer are related to l...Risk of womb cancer varies according to the type of HRT used
... the other hand, HRT containing both oestrogen and progesterone causes the greatest increase in breast cancer. Since breast cancer is much more common than endometrial cancer, combined HRT poses the greatest overall cancer risk." In an accompanying comment Louise Brinton and colleagues (National Cancer Institute,...HIV treatment not affected by hormonal birth control
Estrogen and progesterone hormones in birth control do not influence the effectiveness of highly active antiretroviral therapy (HAART), which is used to treat HIV infection, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutio...Other highlights in the May 4 JNCI
...sis suppressor gene called Nm23-H1 in estrogen and progesterone receptor-negative breast cancer cells via the glucocorticoid receptor. Patricia S. Steeg, Ph.D., of the National Cancer Institute, and colleagues tested whether treating hormone receptornegative breast cancer cells with MPA could decrease the ability...Breast tumor's biological traits guide hormone therapy
...was positive both for estrogen receptors (ER+) and progesterone receptors (PgR+). For women whose tumors were ER+ and PgR+, the best course appears to be tamoxifen for two years and then aromatase inhibitor treatment after two years. If the tumor is ER+ and PgR-, however, upfront treatment with an aromatase inhi...High levels of estrogen during pregnancy associated with improvement in psoriasis
...w psoriasis fluctuates in pregnancy and correlated progesterone and estrogen levels in pregnancy with psoriatic ch... correlated with improvement in psoriasis, whereas progesterone levels did not correlate with psoriatic change," the authors write. "We believe that further examina...Other highlights in the May 18 JNCI
...s testosterone or androstenedione or low levels of progesterone had an increased risk of breast cancer. Sex steroi...t cancer, whereas elevated blood concentrations of progesterone were associated with a decreased risk of breast cancer. Breast cancer risk was not associated with b...Going to extremes to improve human health
...ainting than men, he also studies how estrogen and progesterone influence blood pressure regulation. Minson is the winner of a 2005 American Physiology Society's Outstanding Young Investigator Award (his second since 2000) and a similar national honor conferred in 2002 by the American College of Sports Medicine. ...The Cochrane Library newsletter, 2005, issue 3
...ake oral contraceptives that combine oestrogen and progesterone (combined oral contraceptives - COC) continuously. Continuously-dosed COCs treat conditions like endometriosis, dysmenorrhoea and symptoms associated with monthly menstruation. Many women, however, simply want to avoid menstruation, leading to less i...Infertility researchers identify one gene's critical role in the human embryo implantation process
...es the expression of the enzyme. After ovulation, progesterone production further heightens the expression of the...p-regulation of the enzyme (when both estrogen and progesterone are present) facilitates the production of L-selectin ligand which enables implantation. When only p...Testosterone therapy improves sexual function in post-menopausal women
...cing declining levels of the hormones estrogen and progesterone which are known to keep the vagina and uterus healthy; estrogen is also involved in the health of bones and keeping HDL at healthy levels. Changes brought on by menopause can cause unwelcome side effects in women such as "hot flashes" and problems wi...Studies find no evidence that estrogens in soy increase uterine cancer risk
...o address that risk a combination of estrogen and progesterone has been shown to increase risk of breast cancer. Soy and some other plants contain estrogen-like compounds called isoflavones or phytoestrogens. These plant estrogens are thousands of times weaker than the estrogen produced by the body, but may be p...Higher placental weight associated with increased maternal breast cancer risk
... risk of breast cancer. Serum levels of estrogens, progesterone and placental growth hormones are many times higher during pregnancy than during other periods of life, and pregnant women also are exposed to elevated levels of insulin-like growth factors. During pregnancy, these markers have been inconsistently a...Study demonstrates safety of oral contraceptives in women with lupus
...on JP, et. al. The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial," Ann Intern Med 2005;142:953-962). "There are settings in which estrogens might provide benefit," say the authors. Among women with lupus, they say, ...Oral contraceptive pill may prevent more than pregnancy
...strogen (ethinyl estradiol) and a potent synthetic progesterone (for example norethindrone), highly effective contraception is achieved by diminishing the levels of FSH and LH, thereby reducing metabolic activity of the ovary including the suppression of ovulation. Several studies over the last 30 years report...BRCA1 gene found to inhibit two sex hormones, not just one
...hat are dependent on hormones. They focused on the progesterone hormone, in part, because of the observation that ...omen who use only estrogen replacement. The use of progesterone in the breast is tightly regulated and is primarily activated when growth in cells is needed, such a...Unique vascular dysfunction in women's heart disease described in major journal supplement
...evels before menopause and decreasing estrogen and progesterone levels after menopause are believed to influence IHD in women." Premenopausal estrogen deficiency due to ovarian dysfunction may be a significant risk factor for IHD for younger women. Women with disruption of ovulation and decreased estrogen produc...Stressed-out women more likely to miscarry early
...levated cortisol levels were associated with lower progesterone levels---a hormone that prepares the uterus for the implantation of the fertilized ovum. "The two pieces of research are consistent in this sense," Nepomnaschy said. The next step, Nepomnaschy said, is to attempt to replicate these results in a larg...Genes and environment interact to promote cancer
...cells to the effects of hormones such as estrogen, progesterone and testosterone. In 2004, Duke researchers showed that an industrial solvent (EGME) and a commonly prescribed drug, Valproic acid, potently boosted estrogen and progestin activity inside cells. The elevated hormone levels are likely responsible for ...Evidence of estrogen and progesterone hormone allergy has been discovered by Texas researchers
...e experiencing allergies to their own estrogen and progesterone hormones, Texas researchers have discovered. Russe... cycle had higher levels of IgE antibodies against progesterone and estrogen than control subjects. An increase in IgE antibodies is typically associated with aller...