Using coxibs and NSAIDs to treat osteoarthritis
...h respect to use of NSAIDs, both non-selective and selective (so-called COX-2 selective agents or coxibs). Adverse reactions related to the gastrointestinal tract, particularly with the n...Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
...n the field is that Parkinson's disease involves a selective loss of dopamine neurons. The truth is, if you look at postmortem Parkinson's disease brains, you will see that both dopamine and norepinephrine neurons are gone," Dr. Weinshenker explains. "We know that norepinephrine is important for regulating the...Bioengineering to prevent iron deficiency?
Using selective plant breeding and genetic engineering could be used to reduce the incidence of iron deficiency worldwide by improving the quality of dietary iron, conclude authors of a Seminar in this weeks edition of The Lancet. Dr Michael Zimmerman, Laboratory ...'Heroes of Chemistry' honored for medical, energy, environmental breakthroughs
..., Fairfax, Va. , developed PxMax, the world's most selective catalytic process for producing para-xylene, a hydrocarbon and key component in the world's most important polyester, polyethylene terephthalate (PET). PET has myriad uses, including woven materials in clothing and home furnishing, containers, LCD's,...Rutgers professor Bart Krekelberg is named 1 of 20 US Pew Scholars for 2007
...d his work in vision and eye movements. The highly selective program supports researchers in studying unexplored areas so they can generate the knowledge that may lead to new medical treatments and save lives. Krekelberg is the only researcher in New Jersey named a 2007 Pew Scholar in the Biomedical Sciences.W...Shoulder tapping -- Young males are most willing to purchase alcohol for underage youth
...e is probably higher because youth are most likely selective in who they approach and where. Furthermore, added Toomey, one in five young men entering alcohol establishments in this area would have been breaking the law if our requesters had actually been under age 21. There are serious implications for so...Progress toward an antitumor vaccine
...ctious diseases: immunization. The production of a selective vaccine is not a trivial task, however. A team led by Horst Kunst at the University of Mainz has now found a way to bind a molecule that is typical for tumors to a carrier protein without irritating the immune system. As they report in the journal An...Brightening prospects of using fluorescent nanotubes in medical applications
...ters to burn away cancer cells. He has developed a selective method for attaching the gold clusters to the surface of tumors and then exposing them to wavelengths of light that cause them to grow hot enough to destroy nearby cells. The approach has one drawback: He doesnt have an easy way to identify the locat...Low libido in menopause linked to trouble sleeping
...Like depression itself, treating depression with a selective serotonin reuptake inhibitor (SSRI), the most common type of antidepressant medication, can interfere with interest in sex. Likewise, she added, although systemic hormone therapy with estrogen can reduce vaginal dryness, it can also lower womens natu...Antidepressant does not improve symptoms in advanced cancer patients without major depression
...jor depression. They conclude: Treatment with a selective serotonin reuptake inhibitor [antidepressant] should be reserved for those with a proven indication....Human stem cell treatment restores motor function in paralyzed rats
...re still partially connected, but there has been a selective loss of inhibitory neurons in the spinal cord. Since these cells are necessary for coordinated motor activity, our research aims to replace these lost neurons by grafting new spinal stem cells, which repopulates the pool of degenerated neurons. F...Investigational nonstimulant Guanfacine XR significantly improved child, adolescent ADHD symptoms
...release (GXR, previously referred to as SPD503), a selective alpha-2A-adrenoceptor agonist. These data from tw...7 years. "Guanfacine extended release, the first selective alpha-2A-adrenoceptor agonist to be tested in well-controlled studies as a treatment for ADHD, holds...Ireland Cancer Center researcher lays out benefits of aspirin to prevent colon cancer
...high-risk subjects who were given aspirin or COX-2 selective NSAID inhibitors and observational trials have associated a decreased risk of colon cancer with aspirin use," writes Dr. Markowitz in the editorial. "The researchers' findings provide powerful support for the role of COX-2 as a key mediator in the de...New study demonstrates that Lubiprostone may improve symptom relief rates in adults with IBS-C
...f disordered defecation. Lubiprostone is a novel selective chloride channel activator that has been shown to be effective and well-tolerated in a number of well-controlled clinical trials in patients with chronic idiopathic constipation. Lubiprostone is marketed in the U.S. as AMITIZA, a 24-mcg gelcap that w...Commercializing university research -- Hopping robots, liquid shoes, electricity from heat
...le substrates that will allow highly sensitive and selective detection of the key enzymes (proteases, matrix metallo-proteases, lipases, amylases) associated with inflammatory cascade. David Kriegman, professor of Computer Science and Engineering, for a project titled, "Face FX: Easy, Effective, Online Pho...Heart failure medication does not improve survival, compared to more widely used medication
...to the short duration of treatment in the trial, a selective effect of levosimendan in specific subgroups, or the lack of a true difference between the 2 drugs. Further studies are needed to distinguish between these possibilities," the authors write. ...Antidepressants safe for children and adolescents
..., with 1,162 participants. The drugs used were the selective serotonin reuptake inhibitors (SSRIs) nefazodone, venlafaxine and mirtazapine; all of the studies were randomized and placebo-controlled. Researchers found that one in 100 participants in the studies included in the meta-analysis had new-onset su...Fragile X, Down syndromes linked to faulty brain communication
...ee that cells with a mutated Fmr1 gene have a very selective flaw: they are less likely than normal cells to reach out and form connections, or synapses, with their neighbors. Although normal cells in the mosaic brain can reroute around these potential dead ends, the resulting neural network has fewer cells an...Contrast agent puts new light on diagnosing breast cancer
...iopsies are needed. Because this agent is highly selective in targeting the product of malignant tumors, this approach may prove most useful for monitoring women who have dense breast tissue, or those who are at a higher-than-average risk for developing a malignant breast tumor, Frangioni says. For screeni......ief is needed, physicians should suggest the least selective COX-2 inhibitors first, moving progressively toward more selective COX-2 inhibitors, which are at the bottom of the list, only if needed. All drugs should be used at t...