NIH scientists target future pandemic strains of H5N1 avian influenza
...apeutically against human-adapted mutants. They vaccinated mice with the material from viruses they altered to contain the mutant receptors, and they discovered one broadly reactive antibody that could neutralize both the bird- and human-adapted forms of an H5N1 virus. According to Dr. Nabel, their findin...UK and other European countries should introduce universal childhood hepatitis B vaccination
...ven other European countries should be universally vaccinated against hepatitis B to eliminate the major public-health impact of this disease, according to a Review published in the June issue of The Lancet Infectious Diseases. Infection with hepatitis B causes between 500,000 and 1.2 million deaths per year ...Meningitis: effectiveness of preventive vaccination demonstrated
... Their investigation revealed that in the villages vaccinated at that date, two to three times fewer subjects were recorded as suffering from the disease. The polysaccharide vaccine could help avoid up to 72% of cases in subsequent epidemics. These results speak in favour of adopting a strategy of routine va...Vaxfectin-formulated measles DNA vaccine elicits long-term protection in nonhuman primates
...t Week 55, resulting in complete protection of all vaccinated animals against disease symptoms. None of the vaccinated animals had detectable levels of measles virus at any time point tested, in contrast to negative con...Papillomavirus vaccine could reduce rate of vulval and vaginal cancers
...effect of vaccination is expected in girls who are vaccinated in early adolescence, before exposure. The effect of vaccination in the general population of sexually experienced young women is expected to be lower initially, due to prevalent HPV infection. "This intervention could greatly reduce the morbidity,...Family members most often source of whooping cough in young infants
...d, particularly to infants who are too young to be vaccinated themselves, so that steps can be taken to prevent ...ve lives. Newborns who are too young to be fully vaccinated against the disease are more vulnerable to severe pertussis and face the possibility of serious comp...Insight on fruit fly immune system could lead to new types of vaccines, Stanford researchers say
... who is first author of the study. She essentially vaccinated over a million flies, typically doing 7,000 in a d...received just saline solution. Those that had been vaccinated lived just as long - about one month - as a separate group that had not been infected. To ensure i...Preclinical results of Geovax's AIDS vaccines demonstrate potential to protect against disease
...temporarily reduced virus levels, the monkeys were vaccinated with the SIV version of GeoVax's DNA/MVA vaccines....ued. The SIV virus levels temporarily rose in the vaccinated individuals, but were later "controlled" (reduced to much lower levels) by immune responses raised b...Flu experts call for mandatory shots for health care workers
...s, and other health workers caring for patients be vaccinated against influenza each year or decline in writing. It is the strongest call yet to plug a critical weakness in the nation's flu preparations. The Infectious Diseases Society of America (IDSA) is issuing the call to Congress and the Administration as...Anthrax attack posed greater potential threat than thought
...be unexposed; and, for comparison, six individuals vaccinated against B. anthracis, two confirmed to have had anthrax, and 12 with no known B. anthracis exposure. The results: Immune responses occurred not only in subjects in or near the Daschle office but also in those elsewhere in the Hart building, or even...RAND study finds vaccination of nursing home staff, residents, key to reducing flu outbreak
...aff and more than 89 percent of the residents were vaccinated for influenza. Researchers defined clusters of i...ommunity for encouraging health care workers to be vaccinated against influenza, including recommendations from the Joint Commission on Accreditation of Healthcar...Bird flu vaccine additive may stretch supply
...N2 is itself a pandemic threat. The researchers vaccinated 96 young adults who were divided into eight groups...uthor of the study. "What vaccines do is cause the vaccinated person to produce antibodies in their bloodstream. The higher the antibody levels, in general, the ...H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses
...tion by naturally occurring virus. The researchers vaccinated 48 volunteers with non-adjuvanted H9N2 vaccine (ma...e at one of the same four dosages. Volunteers were vaccinated twice, with inoculations spaced 28 days apart. An avian flu vaccine, like the seasonal flu vaccin...Unique results from Swedish study of HIV vaccine
...the injected DNA codes. The trial subjects were vaccinated on three occasions with this vaccine using a needle-free method of injection. In order to enhance the effect, the researchers also gave the subjects a fourth dose of a vaccine in which parts of the HIV virus DNA had been integrated into another virus...Crafting messages with meaning for HIV testing and research
...olving parents TM attitudes toward children being vaccinated for sexually transmitted diseases. The first phase of this behavioral study will use focus group and individual interviews to identify obstacles to HIV testing and attitudes about an HIV vaccine clinical trials. Interviews will be conducted in S...New hope in cancer vaccines emerges as novel therapies are developed and tested
...d in patients at the NIH, stem cell donors will be vaccinated with the patient's tumor antigen. "The donor has a healthy immune system and can mount a reaction against the antigen," says Neelapu. Those primed stem cells will then be given back to the patient, "improving the chance of a graf-versus-myeloma effe...Longer needles best for infant immunization
Infants vaccinated with a long needle experience fewer reactions but ...er-shorter needles. Significantly fewer infants vaccinated with the longer needle experienced severe local reactions. Immunogenicity following injection with t...Radiation-killed bacteria vaccine induces broad immune response in mice
...eria with lethal doses of gamma radiation and then vaccinated a group of 10 mice twice with the irradiated bacte...imals). All the unvaccinated mice and all the mice vaccinated with heat-killed Listeria died, but 80 percent of the mice vaccinated with the irradiated bacteri...New strategy more sensitive at detecting cervical cancer than smear test
...ical triage is a theoretically logical policy [for vaccinated women] that protects the effectiveness of cytological testing by allowing it to be done where prevalence of lesions is artificially high, as is the case when reading smears from HPV-positive women". ......of the journal posing the question, "Who should be vaccinated against human papillomavirus?"- as well a review piece on HPV infection in men in the same issue. The HPV vaccine protects women from acquiring two types of HPV, a sexually transmitted disease believed responsible for 70 percent of cervical cancer ca...