Using coxibs and NSAIDs to treat osteoarthritis
...eoarthritis and Cartilage, with particular concern about their impact on appropriate use of these agents. The Editorial questions the recommendation made in the AHA statement which described a stepped care approach to pharmacologic therapy for musculoskeletal diseases. The Editorial strongly recommends...Patient-centered approach can backfire
...h toward healthcare. That means educating patients about their conditions, encouraging questions and collab...on. So they leave the appointment feeling confused about what they're supposed to do, or with information overload." Christensen and his team recruited 16 ...Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
...hould IOP fluctuation be damaging" Theories abound about the mechanisms of retinal ganglion cell damage in glaucoma, but no single cellular or molecular cause satisfactorily explains the condition in all patients, Dr. Caprioli writes. Long-term variability may disrupt homeostatic mechanisms. Irregular and ...RAND finds cases of undiagnosed diabetes drop sharply
...tudy author James P. Smith found that in 1999-2002 about 20 percent of American men who had diabetes did no... had the disease, in contrast to 25 years ago when about half of the men with diabetes were undiagnosed. Ethnic disparities among those with undiagnosed di...Pot bellies linked to early signs of cardiovascular disease
...circumference alone. In other words, we may obsess about unsightly cellulite on our hips, but its the pot belly we ought to worry about. In our thirties and forties, we often gain three to four inches in the midsection, said James A. de Lemos, M.D., F.A.C.C., a professor of medicine and director of the ...Study says COPD testing is not measuring up
...ble to them, and patients need to actively inquire about their care. The National Lung Health Education ...reath with exertion, or wheezing, ask their doctor about having a spirometry test performed....Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
...tart showing symptoms of Parkinson's disease until about 80 percent of their dopamine neurons are gone, whi...,6-tetra-hydropyridine (MPTP) at a dose that kills about 80 percent of the dopamine cells, but observed no motor impairments in the mice. Surprisingly, when ...Grandparents, older adults encouraged to seek help for a sleep disorder
...ing their sleep patterns. While older adults need about seven to eight hours of sleep each night, many oft...f the journal SLEEP have some interesting findings about older persons and sleep: The effects of insomnia are different in older and younger people. ...Adverse housing conditions contribute to diabetes risk
...to participants in their homes. They gathered data about health status, access to medical care and demograp... finding in and of itself," Schootman says. "Think about how many middle-aged African-Americans live in a place like St. Louis, and if our sample is at all r...1 of 2 pediatric kidney disease research centers in world established
...hile clinical observations will help us learn more about kidney disease and provide data that could spark new investigations. This fits in with NIHs focus on a bench-to-bedside approach to translational research as a way of expediting clinical cures in all disciplines. Researchers at the Center are working...Draining away brain's toxic protein to stop Alzheimer's
...ple. Levels of sLRP in people with Alzheimers were about 30 percent lower than in healthy people, and the s...and Neurosurgery Research. We arent really talking about massive amounts of amyloid-beta. Even a small malfunction in the elaborate system that carries it in...Reanalysis of controversial meta-analysis says writing off rosiglitazone may be premature
...risk of rosiglitazone will resolve the controversy about its safety." In an Annals of Internal Medicine a...tically significant. There was greater uncertainty about the risk associated with rosiglitazone than was originally reported, with neither increased nor decr...Nationwide data highlight encouraging trends, 'staggering' costs of ESRD
...ters. At the same time, there is continued concern about overaggressive use of drugs called erythrocyte-stimulating agents (ESAs) for the treatment of dialysis-related anemia. Most important, the probabilities of survival for U.S. ESRD patients have improved steadily since the late 1980sespecially remark...New study counts the economic cost of persistent pain in Australia
...sins said there has been an explosion of knowledge about persistent pain and its treatment over the past 10 years, yet it remains under-treated or untreated for many reasons. It is now possible to manage persistent pain in 70-80 per cent of patients yet fewer than 10 per cent actually obtain pain relief...Reductive stress linked to heart disease
...ess and its influence on disease, he said. This is about balance needed in the environment of our cells, and it can have profound consequences on the treatments of heart disease and other serious disorders. ...Some women benefit more from exercise when emphasis is on health, not appearance
...uctor who emphasized appearance by making comments about how the exercise would tone their legs or other bo... they worked out at moderate or vigorous intensity about 3.3 times a week. The women participated in one of four 45-minute step-aerobics classes. The same ...Stanford researchers find culprit in aging muscles that heal poorly
...ue, also known as fibrosis. "That says something about how cells decide who they're going to be. Even if ...he fundamental conclusions (of the two papers) are about Wnt signaling and aging."...Seat belt injuries could signal more serious trauma in children
...ctims, they should have a high degree of suspicion about more serious injury. Car accidents, the most common cause of injury and death in children, are also the most common cause of spinal cord injury in children and adolescents. Boys are more affected than girls, and the incidence increases with age. C......hs, say Dr Dee Mangin and colleagues. But concerns about equity of access to treatments have led to preventive interventions being encouraged regardless of age, and this can be harmful to the patient and expensive for the health service. In rapidly ageing populations, we urgently need to reappraise the c...