Baxter and Jerini advance program to develop non-intravenous haemophilia therapy
...ent, with the potential for milestone payments for achieving discovery, preclinical and clinical goals as well as royalties in the event of marketing approval....Rheumatoid arthritis patients can benefit from Enbrel in combination with methotrexate
...ears (mean DAS 2.2)1. The proportions of subjects achieving clinical remission by adding ENBREL to methotrexate and adding methotrexate to ENBREL at four years were 41.8% and 38.2% and were not statistically different from each other nor compared to the combination group. Ailsa Bosworth, chief executive, Nati...New evidence shows MabThera inhibits joint damage in patients with rheumatoid arthritis
...one or more TNF inhibitors, the number of patients achieving remission doubled from 6 % following an initial co... second course. A similar trend was seen for those achieving the hard-to-reach goal of a 70 % improvement in symptoms (ACR70), with responses increasing from 12 ...World's first approval of new HIV drug TMC114 provides potent new treatment option with FUZEON
...as a strategy to achieve this goal.1,2 Until then, achieving an undetectable viral load in these patients had not been considered a realistic target. "I have treated people living with HIV for many years who, for the first time, achieved undetectable viral levels with the combination of TMC114 and FUZEON. Thi...For men with prostate cancer, treatment information fails to address fears
...cal risk is necessary, it is hardly sufficient for achieving quality in patient-centered decision-making." It is important to give greater attention to patients' fears, misconceptions, and anecdotal influences....Increased collaboration and awareness critical to managing climate variability and saving lives
...and Change conference to discuss practical ways of achieving better management of climate risks in their short- and long-term operations. Economies of all societies are vulnerable to climate change, but with limited resources, developing countries are particularly at risk of incurring higher losses, both in...Focus on weight undermines motivation for healthy lifestyle changes among people of all sizes
...udy suggests our media and cultural obsession with achieving a certain weight does little to convince couch potatoes of any size to abandon their favorite sofa cushions and get active. In fact, those messages may actually undermine motivation to adopt exercise and other healthy lifestyle habits. Published i...Commonwealth Fund commission says the US health care system needs thorough transformation
...iliated networks of rural hospitals and physicians achieving virtual integration through advanced information technology. The report was informed by an exhaustive review of evidence on health system performance in terms of coverage and access, quality and safety, efficiency, and system capacity to innovate a...Stroke risk should determine anti-clotting treatment
...rhythm disturbance. Rate control usually involves achieving a ventricular rate (pulse) of 60 to 80 beats per minute at rest and between 90 and 115 beats per minute during moderate exercise. Also new in the guidelines, catheter ablation -- a procedure that corrects irregular heartbeat with radiofrequency ene...Longer needles best for infant immunization
...fit of using the longer needle at each dose whilst achieving comparable immunogenicity, say the authors. They suggest that vaccine manufacturers and national policymakers use this evidence in recommendations for infant immunisation. With increasing parental attention focused on the safety rather than the ef...Sub-Saharan Africans with HIV may achieve favorable levels of antiretroviral therapy adherence
...a pooled estimate of 55 percent of the populations achieving adequate levels of adherence and African studies (12,116 patients total) yielded a pooled estimate of 77 percent, indicating a higher level of ART adherence in Africa. "The findings from this systematic review and meta-analysis suggest that ART ad...Drazner to lead UT Southwestern heart failure and transplant program
... transplantation. He also has been instrumental in achieving UT Southwestern's tremendous survival rates for heart-transplant patients, which consistently rank in the top 10 in the nation and are the best in Texas. Dr. Drazner succeeds Dr. Clyde Yancy, who served as medical director since 1993. The Heart Fail...Why we need better estimates of global demand for an HIV vaccine
...emand for an HIV vaccine," they say "would help in achieving several policy and advocacy objectives." These objectives, they say, include:persuading governments and industry to invest more in research and product development convincing donors to finance vaccine purchases, in advance or at the time of uptake, g...Mexico's health-system reforms showing encouraging results
...lies (about 22 million people) and is on track for achieving universal coverage by 2010. Dr Frenk states: "A hallmark of the Mexican experience has been a substantial investment in research to design the reform, monitor progress towards its implementation, and assess its results. This is a clear example of t...Walking not enough for significant exercise benefits
... to their exercise. Across your day, while you are achieving those 10,000 steps, take 200 to 400 of them at a brisker pace." "You've got to do more than light exercise and move towards the inclusion of regular moderate activity, and don't be shy to interject an occasional period of time at the vigorous level....Emotional control circuit of brain's fear response discovered
...ponse did not overwhelm subjects performance, thus achieving emotional control.facial expressions. This paper adds important regulatory circuit information about the fear response in the amygdala, said Dr. Hirsch. For example, if someone is walking on an empty street at night and hears a loud banging sound in...The Starr Foundation launches multi-institutional cancer consortium
...ing institutions (profiled below) are committed to achieving dramatic progress in addressing the enormous challenges posed by cancer and in seizing one of today's greatest scientific opportunities. The Broad Institute of Harvard and MIT located in Cambridge, Mass., is a new research collaboration among MIT, H...Landmark study of islet transplantation reveals potential benefits in uncontrolled type 1 diabetes
...had benefited from the technique, with 16 patients achieving freedom from insulin injections and 10 requiring insulin, but maintaining improved control of blood glucose levels. After two years, five of these 26 patients remained insulin independent, while the remainder continued to require less insulin by inje...Early results indicate radiofreqency ablation useful in treating ovarian cancer metastasis
...ctric current to kill tumor cells, is effective in achieving local control in selected patients with metastasis from ovarian cancer, according to a preliminary study conducted by the department of radiology at Massachusetts General Hospital in Boston, MA. The study consisted of six patients with advanced ov...How low should we go? Researchers find no clear evidence for ultra-low cholesterol targets
...entify any valid clinical evidence supporting that achieving a low LDL level was important independent of statin therapy. The problem is not solely a lack of studies, but how past studies have been analyzed, says Hayward. Many studies have looked at associations between LDL and outcomes, but such studies did...