New screen-and-treat methods for cervical cancer significantly reduce cancer precursor lesions
...HPV) DNA testing and visual inspection with acetic acid (VIA), followed by treatment using cryotherapy for all eligible women with positive test results, were found to perform as well or better than traditional cytology-based screening (Pap smear) for identifying high-grade cervical cancer precursor lesio...ACTOplus met (pioglitazone HCl and metformin HCl)
...ic acidosis. Lactic acidosis, a buildup of lactic acid in the blood, can be fatal in about half the cases. Because lactic acidosis occurs most frequently in people with kidney problems, ACTOplus met should not be used in people with kidney disease or in people 80 years of age and older whose kidneys do ......rtmouth College, the man-made version of oleanolic acid used in the study is dubbed CDDO-Im*. Investigators at Johns Hopkins teamed up with the Dartmouth chemists to determine whether the compound could help flush out of the body chemicals that trigger the development of liver cancer. The researchers use...Cervical cancer screening programs for low-resource areas appear effective and safe
...(HPV) DNA testing or visual inspection with acetic acid (VIA; a weak acidic solution) followed by treatment of lesions using cryotherapy (medical treatment that involves application of nitrous oxide to lesions and a device using very low temperatures) of all eligible women with positive test results. Cryo...Primrose oil component cuts levels of cancer-causing gene Her-2/neu
Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report. ...Mayo Clinic: Sinusitis is common yet often overlooked cause of chronic cough
...he top three reasons for chronic cough, along with acid reflux and rhinitis, inflammation of the nasal passages." Chronic cough is defined as a cough lasting over three weeks. According to Dr. Lim, an estimated 23 million Americans see their physicians each year for cough. How many have been coughing for ...Focus on lung cancer: How to prevent and treat it
... enzymes involved in the metabolism of arachidonic acid (AA) as potential targets for the prevention of a variety of epithelial cancers (in cells that line organs). AA, which is involved in inflammatory and other processes that regulate organ function, is generated from lipids and is metabolized by cyclo...Scientists show how thinking can harm brain cells
...odegenerative disease has been glutamate, an amino acid that normally acts as a neurotransmitter. Excess glutamate, however, can overly excite neurons, causing damage and death a process called excitotoxicity. Some drugs developed for the treatment of Alzheimer's disease, for example, are designed to low...Tryptophan no turkey in boosting immune system, Stanford study shows
...new ground on the effects of tryptophan - an amino acid found in turkey, among other foods, that is rumore... when ingested on an empty stomach). But the amino acid itself does play a vital role in sleep and in control of mood. And Steinman's findings add to the gr...Aspirin & similar drugs may cut risk of esophageal cancer in people with Barrett's esophagus
...ty is a driving factor, partly because it promotes acid reflux, a key risk factor for both Barrett's and cancer. But it's pretty likely that there's something else going on, too, because obesity is just as high in women and African Americans. Hormonal factors also might be important, but at this point we ...Common anti-seizure drug could be effective for lupus patients
...University School of Medicine. The drug, valproic acid (Depakote), prevents skin disease and reduces the ...rest University Baptist Medical Center. "Valproic acid may be a potential cost-effective disease-modifying agent in lupus," Mishra reported today (Nov. 16)...Aspirin may help the heart, but one in ten patients will also develop an ulcer, new research shows
...arning symptoms, like indigestion, abdominal pain, acid reflux, nausea or bloating. In fact, their ulcers were undetected until the patients underwent an endoscopy. The study was led by gastroenterologist, Professor Neville Yeomans - the Dean of the University of Western Sydney's Medical School. The team ...Study provides first estimate of US population affected by Barrett's esophagus
... waking during the night due to heartburn pain and acid regurgitation. However, some people with Barrett's don't show symptoms of the disease and it often goes undiagnosed for years. While the exact cause of Barrett's is not clear, people with chronic GERD, obese people, men and Caucasians are at greate...Disruption of gene interaction linked to schizophrenia
...makes an enzyme that breaks down proline, an amino acid that mimics the action of glutamate on most nerves in the brain. When PRODH activity is low, proline levels are high, creating an excess of excitatory activity leading to overall hypersensitivity of nerve cells to stimulation that might contribute to...The heat is on: Why some cholesterol-lowering drugs cause hot flashes
... show why the cholesterol-lowering agent nicotinic acid also commonly causes flushing or "hot flashes" tha...The authors found that activation of the nicotinic acid receptor GPR109A by nicotinic acid can produce different responses dependent on the location of this...JCI table of contents: December 1, 2005
... show why the cholesterol-lowering agent nicotinic acid also commonly causes flushing or "hot flashes" tha...The authors found that activation of the nicotinic acid receptor GPR109A by nicotinic acid can produce different responses dependent on the location of this...The role of Type II Collagen in rheumatoid arthritis
... binding reactions. CII treated with hypochlorous acid was the most reactive, followed by CII treated with peroxynitrite, glycation, and hydroxyl radical, respectively. In contrast, only 1 non-RA sample showed strong antibody binding to modified CII. "The present findings support the possibility that ch...Global meeting identifies cost-effective approaches to cervical cancer prevention
...isit approach" using Visual Inspection with Acetic acid (VIA) is safe, acceptable, feasible and cost-effective Cervical cancer is the leading cause of death among women in developing countries. From December 4-7, 2005, Ministries of Health, U.S. government agencies, leading clinical experts and reproducti...What can change in the brain? Electrical synapses, research shows
... type of neural trigger that responds to the amino acid glutamate, a trans-mitter molecule in the brain. The result: a long-lasting, 20 to 30 percent reduction in electrical synapse strength. While previous studies have shown a related effect in the electrical synapses of goldfish, Landisman and Connors a...Artificial light at night stimulates breast cancer growth in laboratory mice
...nterferes with the tumor's ability to use linoleic acid as a growth signal, which causes tumor metabolism and growth activity to shut down." To test this hypothesis, the researchers injected human breast cancer cells into laboratory mice. Once these cells developed into cancerous tumors, the tumors were i...