Carnegie Mellon researchers open window into the ability of humans to recognize faces
...ir expectations, the regions of the brain that are activated when normal individuals perceive and recognize faces also are activated in individuals with congenital prosopagnosia (CP). Behrmann and Avidan will summarize the results of......ently, his lab demonstrated how the ATM protein is activated by DNA damage. Dr. Kastan is the 2005 AACR Annual Meeting Chairperson and, as such, he is chairing the opening plenary session, entitled "The Impact of Scientific Discovery on Cancer Diagnosis and Treatment." Clifton Leaf , executive editor, Fortune...Charter activation brings space dimension to European emergency exercise
...onal Charter on Space and Major Disasters is being activated so rescue teams will receive satellite images of t...r man-made disasters. To date the Charter has been activated more than 70 times. Following the UNISPACE III conference held in Vienna, Austria in July 1999, the...Smart plastics change shape with light
...hreads into the body through a tiny incision. When activated by light via a fiber-optic probe, that slender string might change into a corkscrew-shaped stent for keeping blood vessels open. What about staples that open on command, or paper clips that relax as soon as you don't need them anymore? Again, light c...Shape-altering genes linked to ovarian cancer
...scovered that a set of shape-altering genes become activated in ovarian cancer. These HOX genes, better known for their role in normal embryonic development, direct the cancer cells to take a variety of different forms, depending on which of the genes is turned on. The researchers reported their finding in the...American Thoracic Society Journal news tips for April 2005 (second issue)
...fections. Many cytokines/chemokines released from activated immune cells not only take part in the process of antiviral immune response, but are also involved in cell damage and development of organ dysfunction. Determination of these soluble factors in the blood should aid their understanding of the immunol...SKCC's Gennadi Glinsky addresses predicting risk in cancer treatment outcome
... What they discovered is that when this pathway is activated in transformed (cancerous) cells, it may contribute to the survival life cycle of cancer stem cells and promotes tumor progression and metastasis. Thus, when this signature expression is found in tumors, there is a high probability of unfavorable th...Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
.... But in cancer, it is believed that telomerase is activated and intervenes to keep telomeres from shortening, allowing for unlimited cell division. The research group looked at genetic variation of hTERT because abnormal expression of the gene contributes to unregulated cell growth, and expression of the gene...Used in a new way, RNA interference permanently silences key breast cancer gene
...er development. The technique permanently silences activated STAT3, a crucial gene found in some human breast t...breast cancer. When hijacked by a cancer cell, the activated gene is believed to interfere with the ability of key immune cells to attack a growing tumor. Invest...Eliminating enzyme dramatically reduces cardiovascular disease
.... Rudel is also studying how the three enzymes are activated to alter cholesterol. Evidence suggests that a diet high in mono-unsaturated fats, which include olive oil, nuts and nut butters, avocado and sesame seeds, may stimulate transformation by ACAT2. In a study of monkeys, those that were fed a diet high ...Exercise training in ordinary people affects the activity of 500 genes
...ows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals ...erg and co-workers show that hundreds of genes are activated by regular cycle training for six weeks in young healthy men. Some of these genes are most likely li...Immune system lab model overcomes ethical limits on human hematopoietic stem cells studies
...eria, and present it to T cells, which then become activated and orchestrate an immune response. Myeloid cells are immune cells that include granulocytes and monocytes. The investigators demonstrated the model's effectiveness by showing that it could produce the wide variety of T cells needed to respond t...New fat is needed to clear old fat from the system
...athway. "Scientists have argued that PPAR-alpha is activated by fats," says Semenkovich, who also directs the Division of Endocrinology, Metabolism and Lipid Research and is a staff physician at Barnes-Jewish Hospital. "But we've never known which fats or where they come from. This study suggests that new fat ...Study suggests antibiotic may limit or prevent vision problems caused by diabetes
...f them, much like a Pacman TM . Should they become activated and release their toxins in the retina, those toxi... in the U.S. After establishing that microglia are activated early in the course of diabetes, the team compared the mRNA levels of cytokines in the retinas of ra...Blocking the Odc gene is effective in preventing cancers
...r development is significant because Myc genes are activated in up to 70 percent of human cancers. Therefore, a drug that disrupts their activity by disabling Odc might prevent or slow the development of a wide variety of cancers, including breast, colon, lung and prostate cancers. However, while DFMO treatme...Researchers prevent post-traumatic brain damage
... found that it reduced expression of proteins that activated the cell cycle, thus limiting growth of the glial scar and formation of an inflammatory response. The size of the lesion was reduced by more than 80 percent, compared to rats who were not given the drug, and that resulted in a "remarkable improvemen...Newly discovered 'branding' process helps immune system cells pick their fights
...s also knew that when antigen-presenting cells are activated by inflammatory factors or microbial products, they start putting out chemically unstable compounds such as nitric oxide and superoxide. Together, these compounds generate peroynitrate, a highly potent chemical that modifies many proteins. Unanue's ......information. Clean air labeled as "cheddar cheese" activated the same area, but to a lesser extent. The "body o...s to such odors and to identify areas of the brain activated by either pleasant or unpleasant odors. Also, they tested whether a change in the amount of "sniffin...Protein essential for hearing also vital for pain perception
...lly inhibit TRPA1," he said. TRPA1 is known to be activated by pain-producing chemicals such as the pungent components of edibles such as wasabi, horseradish, mustard, cinnamon and Listerine, which explains why they sting the mouth....Penn study points to how COX-2 inhibitors can eventually lead to heart disease
... could be limited, in part, by removing a receptor activated by thromboxane A2, the fatty product of COX-1 in platelets. This mirrors a similar balancing effect between COX-1 and COX-2, which has been noted in the case of blood clotting, blood pressure, and atherosclerosis. This suggests that suppression of th...