Patients with pituitary gland tumors are often misdiagnosed
...timulating hormones that signal the thyroid gland, adrenal glands, ovaries and testes, directing them to produce their respective hormones. These hormones have dramatic effects on metabolism, blood pressure, sexuality, reproduction, and other vital body functions. In addition, the pituitary gland produces gr...Multiple views from CT scans may improve diagnosis
... three views, we saw it was actually involving the adrenal gland," he said. "The multiple views increase our confidence in diagnosis as well as accuracy." Wake Forest Baptist is one of a few centers in the country routinely viewing pediatric CT scans in all three planes. Barnes's co-researchers are Evelyn An...Other highlights in the May 18 JNCI
...men who have elevated blood levels of androgens of adrenal and/or ovarian origin or of estrogens have an incr...ntrations of testosterone, androstenedione, and an adrenal androgen were associated with an increased risk of breast cancer, whereas elevated blood concentrati...Disease progression model of pancreatic cancer developed by Penn researchers
...r metastasizes to the liver, lungs, diaphragm, and adrenal glands, all the same places that human pancreatic cancer metastasizes," says Tuveson. The frequency of metastases to these various organ sites was also highly similar to that seen in humans. In human patients, 60 to 80 percent develop metastases to...Fine tuning drug levels in neuroblastoma patients is effective, St. Jude researchers show
.... This cancer usually arises in the tissues of the adrenal glands. The Phase II study addressed the problem posed by the different rates at which children eliminate or clear topotecan from their bodies. Such differences mean that the standard drug of topotecan might help some children; in others, the drug m...Virtual colonoscopy reveals diseases outside the colon, as well
...he liver, kidneys, pancreas, spleen, gall bladder, adrenal glands, and bladder, plus the lower part of the lungs. In men, the scan includes the prostate; in women, the uterus and ovaries. "Typically, these are patients who are not symptomatic for their extracolonic lesion; that's not what brought them in for......rapid clinical deterioration and bleeding into the adrenal glands, a complication, known as Waterhouse-Friderichsen syndrome, that is usually associated with fulminant bacterial meningitis. Two of the three bacterial strains were resistant to standard antibiotics. In all three cases, the disease progresse...Focus on lung cancer: How to prevent and treat it
... glucocorticoids (steroid hormones produced by the adrenal gland) are particularly effective in inhibiting cancer formation in mice. A recent phase IIb study of inhaled budesonide, a corticosteroid, did not show any efficacy in regressing or preventing precursor lesions for squamous cell cancer, but the tre...Jefferson scientists show protein in heart and adrenal gland plays critical role in heart failure
...e in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have ...sed from two sources nerve terminals and from the adrenal gland, from which they enter the circulation. Dr. Koch and his co-workers wondered if GRK2 and alpha...Hormone aldosterone is promising target for stroke treatment
...c momentum surrounding the hormone secreted by the adrenal gland prompted the journal to ask Dr. Dorrance to ...st things, too much aldosterone resulting from an adrenal gland tumor or abnormal production for unknown reasons is what causes problems, such as proliferati...Collapse of p53 into clumps might be linked to cancer, according to St. Jude
...rtical carcinoma (cancer of the outer layer of the adrenal gland), suggesting a link between clump formation for mutant p53 in adrenal cells and the resulting cancer. Although the current finding only suggests a link between p53 clumps...Loss of caspase-8 makes neuroblastoma more aggressive
...ry models, they generated metastases to the ovary, adrenal glands, kidneys and liver. These metastases have lost expression and activity of caspase-8. These findings suggest that the loss of caspase-8 expression promotes metastases of neuroblastoma cells, the researchers reported. Although the presence or ...Hydrocortisone supplementation improves ventilator weaning
...od by identifying critically ill patients who have adrenal insufficiency and treating them with the hormone h...nitial evaluation, 23 individuals exhibited normal adrenal function and 70 were diagnosed with adrenal insufficiency. Because of the high percentage of adrena...OHSU research reveals the complexities of obesity/cortisol interactions
... that regulates the secretion of cortisol from the adrenal glands, but not in the central portions of the bra...l nervous system, independent of the pituitary and adrenal glands. It also demonstrates that cortisol alone is not the major culprit in weight gain. Glucocorti...JCI Table of Contents, April 3, 2006
...irect result of a related defect called congenital adrenal hyperplasia, essentially an enlargement of the adrenal glands above the kidneys. Interestingly, if the mother is given a cortisol-like drug called dexamet...Do testosterone patches help women with under-active pituitary glands?
...r-active pituitary glands. Loss of ovarian and/or adrenal function can cause many women to experience hypopituitarism or under-active pituitary glands, and therefore low levels of testosterone, which is responsible for producing estrogen. This lack of testosterone can be blamed for loss of sex drive, loss o...OHSU primate center research suggests multiple 'body clocks'
...secondary clock-like mechanism associated with the adrenal gland. The research also suggests a high likelihoo...a separate but likely related clock resides in the adrenal gland. The adrenal gland is involved in several important body functions, such as body temperature r...Stress, alcoholics, and post-traumatic stress disorder
...zed by abnormalities in the hypothalamic-pituitary adrenal (HPA) axis. However, the influence of interaction between these two disorders upon disruptions in the HPA axis is not well understood. A study in the June issue of Alcoholism: Clinical & Experimental Research has found that alcoholics without PTS...Stopping inhaled corticosteroid use causes no problems in cystic fibrosis patient users
...e drug can lead to significant symptoms related to adrenal suppression and insufficiency. Also, among pediatric patients, slowing of linear growth has been a problem for individuals taking the drug for a year or more. Over a 6-month period, the researchers studied 84 CF patients (median age 14.6 years) who ...Studies of married couples, soccer and hockey teams focus on brain's response to stress
...to protect us from threat by sending orders to the adrenal glands to release hormones such as cortisol, which mobilize bodily reserves to help meet the challenge. Systems like blood pressure and blood sugar are geared up, while other processes are temporarily shut down. It's an efficient and effective approa...