Mayo Clinic researchers use pharmacogenetic test prior to chemotherapy to reduce toxic side effects
...etabolism of irinotecan. The test gives scientists advance knowledge of the individual risk for toxicity from irinotecan. As a result, scientists are able to tailor this chemotherapy regimen to the individual, thus reducing toxicity. This kind of customized dosing approach based on a person's genetic makeup ...Test predicts risk of blood clots in women receiving tamoxifen therapy for breast cancer
... clots. The results suggest that testing women in advance for FVL mutations may enable physicians to identify some women who should either use alternatives to tamoxifen or, if good alternatives are not available, use a blood thinner while taking tamoxifen. "Other factors contributing to blood clot risk must...Improvements in critical care decrease risk of post-injury multiple organ failure
...tical care although the relative effect of any one advance on postinjury MOF outcome awaits further study. Nevertheless, our prospectively collected patient data indicate a substantial reduction in the incidence and severity of MOF following severe injury over the last decade." (Arch Surg. 2005; 140:432-440....Researchers largely at fault for health risk studies that influence and confuse the public
...at risk for diseases." Dr. Kupfer believes that to advance medical science and promote public health, research must be both flawless and accurately presented. In order to generate more reliable and meaningful findings, Dr. Kupfer urges researchers to be more precise in defining, understanding and evaluating ...Harvard Medical School and Project A.L.S. join forces to target ALS research
... and a cure for ALS, have agreed to join forces to advance ALS research. Across Harvard, they will identify a...llaboration with Project A.L.S. is one way to help advance the Medical School's mission," he said. ALS (amyotrophic lateral sclerosis), also known as Lou Gehri...ARVO Foundation and Alcon announce significant gift
...Foundation to sponsor several programs designed to advance the progress of vision research. The Alcon grant ...hD. "Alcon has already done an enormous amount to advance research in visual science and ophthalmology and the present gift is yet another example of their co...Mayo collaboration: Discovery blocks breast cancer growth, stimulates immunity
...ients. Even so, he says this is a welcome research advance because breast cancer is the most commonly diagnosed non-skin cancer in women. According to the National Breast Cancer Foundation, this year in the United States more than 211,000 women will be diagnosed with breast cancer and 43,300 will die from it...Homeless prefer aggressive medical treatment
...ss persons should consider options for encouraging advance directives for the individuals they serve." "Advance directives are an important part of end-of-life care," said Paul A. Kvale, MD, FCCP, President of the American College of Chest Physicians. "Physicians should encourage all patients to make their...Transplantation of sperm stem cells restores fertility after chemotherapy
...se. Now, in a study appearing online on June 16 in advance of print publication in the July 1 issue of the Journal of Clinical Investigation, Akira Tsujimura and colleagues from Osaka University describe a way in which healthy germ cells, including spermatogonial stem cells, can be distinguished and complete...New computer program uses brain scans to assess risk of Alzheimer's
...ccuracy who will develop Alzheimer's nine years in advance of symptoms, and our projections suggest we might be able to take that out as far as 15 years," says Dr. de Leon, whose longitudinal study is funded by the National Institutes of Health (NIH). "Our basic results will need to be replicated in o...Researchers discover 'window on the brain' that could help treat disorders
...ary patent on the process. "This new computational advance gives us a window on the brain that could be a bre... will facilitate application of NIC discoveries to advance computation and telemedicine services pioneered by EGI. He says CDS eventually could employ as many ...Assuring the supply of vaccines
...cover immunizations, that vaccine prices be set in advance of their development, and that vaccine coverage decisions include societal benefits and costs, including consideration of the impact of the price of a vaccine on recommendations for its use, there were widespread and varied responses. Editorials in t...Neurology Now, patient magazine of American Academy of Neurology, wins national award
... the many contributions associations are making to advance society," said David Gabri, chair of the Associations Advance America Committee. In 2004 the AAN was elected to the annual Associations Advance America Honor Roll for its Donald M. Palatucci Advocacy Leadership Forum, which provides formal advocacy t...Vascular disease most common cause of male erectile dysfunction
...ents in the group. "This is a huge, groundbreaking advance in our field that shows how multidisciplinary sexual medicine really is," states Irwin Goldstein MD, Editor-in-Chief of The Journal of Sexual Medicine. "Coordinating care between the sexual medicine physician and the cardiologist has provided new ev...What don't we know? Science presents the great unsolved scientific mysteries of our time
...er fully answer some of these questions, but we'll advance our knowledge and society in the process of trying," said Donald Kennedy, Science's editor-in-chief. "As Science celebrates its 125th birthday, we've recognized that an examination of science's outstanding mysteries also reflects its tremendous ...Animal research suggests new treatment target for epilepsy
...wly discovered receptors, it would be an important advance in therapy," said William L. Bell, M.D., a specialist in epilepsy at Wake Forest University Baptist Medical Center. Godwin explained that design of improved drugs to target the receptors wouldn't be a cure, but would short-circuit the type of abnorm...Melanoma research receives a massive funding boost
...ey Melanoma Unit have received over $11 million to advance their world-leading research into the diagnosis and treatment of melanoma. Australians have the highest rate of melanoma in the world, with incidence levels up to four times higher than the US and the UK, and up to ten times higher than most other co...Mood lighting: Penn researchers determine role of serotonin in modulating circadian rhythm
...r," says Sehgal. "Disturbances in the late evening advance the body clockan early dawn leads to an early rise." Entrainment was tested in flies by exposing them to a pulse of light during the dark period. Closely resembling the body clock adjustment seen in humans, Sehgal's flies reset their body clock follo...The Children's Hospital of Philadelphia named top U.S. children's hospital, third consecutive year
...our responsibility to care for our patients and to advance the field of pediatric medicine," says Steven M. Altschuler, M.D., president and chief executive officer of The Children's Hospital of Philadelphia. "I am humbled by this recognition. It is our responsibility to continue to work to provide the best ...New study shows use of Lorenzo's oil prevents onset of pediatric neurological disorder
...M.D., CEO of the Kennedy Krieger Institute. "This advance results from truly collaborative efforts between researchers in the medical community, parents and advocates for these patients." There is still no cure for X-ALD, and treatment options are limited to hormone therapy and bone marrow transplants. Whi...