INTERMACS group reveals recent successes to international transplant community
...o help develop advanced medical devices, eliminate adverse effects, and decipher characteristics for a successful transplant. Discussions at this weeks ISHLT meeting will highlight collaboration between INTERMACS and the U.S. Centers for Medicare and Medicaid Services (CMS) on an effort to obtain more robu...Physicians should be able to review performance rates before release
...should employ all possible means to ensure that no adverse determination regarding physician performance be made without prior review by the rated physician, and, when requested by the physician, ratings should be reconsidered by an appropriate and objective group of reviewers. 2. At the time of enrollmen...Antidepressants safe for children and adolescents
...ents a clinician would need to treat to prevent an adverse outcome in one was 10 for major depressive disorder, six for OCD and four for anxiety. The number needed to harm (NNH) the number of patients who would need to be treated for one to be harmed was 112 for major depressive disorder, 200 for OCD and ...Research could lead to treatment for Alzheimer's disease
...l processes and its inhibition would cause serious adverse side effects, Ghosh said. "Unfortunately, all of our early designed compounds that were potent against memapsin 2 also inhibited memapsin 1," he said. "Selective inhibition of memapsin 2, or building selectivity, became very important. The scientif...UCSF brain tumor vaccine trial shows promising results
...d overall survival. According to investigators, no adverse events or toxicity identified were considered attributable to the vaccine. Cheryl Canagelo, a 52-year-old woman from Oakley, Calif., came to UCSF for a second opinion after undergoing radiation and chemotherapy elsewhere for treatment of a glioma....Clinical studies evaluate potential treatments for mouth ulcers
...e patients taking the active treatment experienced adverse effects, including dizziness, headaches, stomach u...clude. "Thus, given the potential for significant adverse effects and the small benefits of the drug demonstrated in this clinical trial, we cannot recommend ...Tip sheet Annals of Internal Medicine, April 17, 2007
...e or hip pain caused by arthritis. Although few adverse side effects were reported, the authors conclude that chondroitin use should "be discouraged." In an accompanying editorial, a writer notes that the market in the United States for chondroitin and glucosamine (usually sold together in the U.S.) top...Study finds drug helps PTSD nightmares
...s," said Raskind. "If there were serious long-term adverse side effects, it is likely we would know about them by now." The relatively small size of the study was due to the easy availability of this generic drug, Raskind said. "If you are doing a study with a new drug, the only way people can get it is to...Study suggests use of stem cell transplantation is beneficial treatment of type 1 diabetes
... insulin use one year after AHST. The only severe adverse effects were pneumonia in one patient and endocrine dysfunction in two others. "This is, to our knowledge, the first report of high-dose immunosuppression followed by autologous nonmyeloablative hematopoietic stem cell transplantation for human ty...Pediatricians rarely provide translation services for patients with little English proficiency
...erlooked problem, given all that we know about the adverse health outcomes that can arise from miscommunication between physicians and their patients. The study was based on the results of a survey of 1,829 physicians from the American Academy of Pediatrics. Of the physicians surveyed, 70 percent reported ...Jefferson scientists find that plavix appears to be safe during and after heart bypass
...n by utilizing clopidogrel postoperatively without adverse bleeding events." "The next step will be to evaluate the addition of clopidogrel in a prospective study," Dr. Whellan says....Novel anti-oxidant and anti-inflammatory agent shows effectiveness on key endpoints in trial
...bo on the primary endpoint of a composite of major adverse cardiovascular events, the study did achieve a number of other important predefined endpoints, including a reduction in the composite of hard atherosclerotic clinical endpoints, composed of cardiovascular death, myocardial infarction (heart attack) a...MERLIN TIMI-36 study provides new safety and efficacy data for unique anti-anginal therapy
...on in recurrent ischemia alone. The data showed no adverse trend in death or arrhythmia in patients receiving ranolazine. Ranolazine is a novel anti-ischemic agent that, unlike other classes of anti-anginal therapy, does not significantly reduce heart rate or blood pressure. The MERLIN TIMI-36 study evalu...EVEREST data on use of tolvaptan published in JAMA and featured at ACC
...d patients receiving conventional care, without an adverse effect on their long-term survival versus placebo....nt & Commercialization, Inc. Safety Data Common adverse events associated with tolvaptan were dry mouth and thirst, which are consistent with the pharmacolo...Studies highlight advances in diagnosis, medical therapy
...milar rates of long-term survival and freedom from adverse ischemic events as more complicated and expensive medical regimens, and reduces major bleeding, minor bleeding, and the need for blood transfusions while simplifying care in high-risk patients with acute coronary syndromes," said Dr. Stone. In the...Studies highlight 'real world' use, safety of drug-eluting stents
...bable stent thrombosis. The combined rate of major adverse cardiac events (MACE) was 10.7 percent. Dr. Dangas will report results from specific subgroups of patients in New Orleans, as well as two-year clinical outcomes. The researchers are considering extending follow-up to five years in order to better ass...Drug/intervention combinations offer benefit in severe CVD
...roups (58% vs. 59%, hazard ratio=1.04). Rates of adverse events, CS resolution and causes of death were similar. Investigators concluded that while the use of TAI resulted in a significant rise in blood pressure the therapy offered no significant benefit in overall mortality rates in high-risk CS patients...Embargoed March/April Annals of Family Medicine tip sheet
...sive medicine whereby the threat or experience of adverse litigation alters clinician behavior. How Physicians Approach Prostate Cancer Screening Before and After Losing a Lawsuit By Alex H. Krist, M.D., M.P.H., et al. OTHER STUDIES IN THIS ISSUE DEPRESSIVE SYMPTOMS SEEN IN PRIMARY CARE JUST AS SEVERE ...Blueberries contain chemical that may help prevent colon cancer
... to be used in lower doses, reducing their risk of adverse side effects, Reddy says. More studies are needed to determine the compounds efficacy and potential for toxicity, he notes. Pterostilbene is an antioxidant that is similar to resveratrol, an antioxidant identified in grapes and red wine that also ......measured. Drug safety was assessed by vital signs, adverse events, laboratory tests and electrocardiograms. The frequency of adverse events was similar between the two groups and included muscle pain and gastrointestinal disorders. ...