Hormone drug type makes survival difference in advanced breast cancer
...aid: "The picture is patchy due to poor quality of adverse event reporting and different study endpoints," in the various trials. However, "the review findings do confirm modest, but real therapeutic benefits from the use of aromatase inhibitors in a variety of clinical settings," Bliss said. Edith Perez...Media coverage of autism differs dramatically
...to lobotomies during the late 19th century despite adverse effects on personality and lack of widespread scientific support. For a current look at the differences between science and the public perception of science, the researchers focused on autism. The Centers for Disease Control estimated that one in e...University Hospitals Case Medical Center researcher awarded
...of globulin intravenously is often associated with adverse effects, but giving the same medicine under the skin has many fewer side effects, so patients can usually treat themselves at home," Berger said. The Talents grants support research trials conceived by researchers and clinicians with an interest in...Risk for stroke, death not higher for sickle cell children with early complications
...at showed that early dactylitis does predict later adverse outcomes," Dr. Quinn said. Researchers reviewed cases of 264 children who are part of the Dallas Newborn Cohort, a unique patient pool started in 1983 when newborn screening for sickle cell disease was launched by the state. Researchers have been a...Topical anaesthetic spray delays ejaculation by five times as long says new study
...ay was used, but continued with the treatment. No adverse effects were found during patient safety checks, which included vital signs, physical findings, electrocardiograms, haematology, biochemistry and urine analysis. "At the moment, only a small number of men with premature ejaculation seek or receive t...Bioterrorism alerts induce anxiety and may pose health risk, Einstein study finds
... measurably raise anxiety levels, which could pose adverse health effects. And, based on their findings repo...population, these should be considered potentially adverse effects that need evaluation." Dr. Cohen and his collaborators from the Ferkauf Graduate School of...Daily use of antidepressants associated with increased risk of fracture in older adults
...espread due to the medication's presumed favorable adverse effect profile. Past studies have found the use of these antidepressants to be associated with an increased risk of clinical fragility fracture (fractures due to falling from bed, chair or standing height), but did not reliably examine such factors a...Selenium supplements may contribute to reduced HIV viral load
...tudy assessment. "The intervention resulted in no adverse events related to the study supplement," the authors write. The two groups had similar selenium levels at the beginning of the study, but after nine months of treatment, the average change in blood selenium level was greater in the treatment group. ...Tamoxifen discontinuation rates surprisingly high in clinical practice
...tes. The most common reason for discontinuation is adverse effects, including mood swings and hot flashes; these are often successfully treated with a specific antidepressant. Discontinuation or non-persistence rates estimated by clinical trials range from 16 to 32 percent. Studies of usage outside clinic...Transdermal vaccine effective in treating Alzheimer's disease in mouse model
... neurodegenerative disease with less likelihood of adverse immune reactions. The study was published online this week in The Proceedings of the National Academy of Sciences. "While many groups have shown vaccinating against the beta amyloid protein (Ab) can reduce Alzheimer's-like pathology including c...Lifestyle changes effective in protecting against Type II diabetes
...f. Lifestyle changes were also less likely to have adverse side-effects. However, the researchers say that both lifestyle changes and prescription drug taking must be sustained in order to prevent the development of Type 2 diabetes. The authors say that as global rates of Type 2 diabetes are likely to do...Health providers could save billions without compromising health care says drug study
...st, which funds family doctors in the area. No adverse events were reported by either patient group and t... At the ten-month review, no patients had suffered adverse events related to the switch. The authors have stressed the importance of carefully selecting ...New fat, same old problem with an added twist?
...actor, requires further study because the apparent adverse impact on insulin metabolism is a troubling finding," he added....Study suggests hip fractures not caused by benzodiazepine use after all
...izure disorders. Concerns about abuse, misuse, and adverse effects of these drugs--including hip fractures among the elderly--have prompted state and national policies intended to regulate access to them. Since January 2006, benzodiazepines have been excluded from coverage through the Medicare Part D drug be...Clear guidelines on oral chemotherapy needed
...ndents at 10 centres reported at least one serious adverse drug event related to oral chemotherapy and respondents at 13 centres reported a 'serious near miss'. The authors conclude that 'prescribing, monitoring and coordination, pharmacy practices and education of patients for oral chemotherapy vary substa...Survey reveals need for standardized oral chemotherapy prescribing practices, safeguards
...ed that between 2004 and 2005 at least one serious adverse drug event related to oral chemotherapy occurred at 10 centers, and 13 centers experienced a 'serious near miss.' "The growing availability of effective oral chemotherapy, especially the new class of 'targeted biologic therapies,' is one of the won...Penn researchers demonstrate ability of new therapy to treat severely elevated cholesterol levels
... liver's ability to produce LDL. The most notable adverse events in the study were loose stools and elevation of liver transaminase levels and accumulation of hepatic fat in some but not all of the patients studied. Rader concluded, "Although our study establishes proof of concept, a longer-term study in ...High level of cardiac biomarker may help predict risk of CVD events in patients with heart disease
...P was associated with a 2.3-fold increased rate of adverse cardiovascular outcomes, even after adjusting for other prognostic markers, including clinical factors, echocardiographic parameters, ischemia, serum biomarkers and functional limitations. "We observed the strongest association between NT-proBNP lev...Scripps research combination therapy obliterates new vessel growth in tumors and retinopathy
...75 percent inhibition of new vessel growth with no adverse affects on normal tissue vasculature. In contrast,... of angiostatic therapies could minimize potential adverse side effects. "The point of the study was to show proof-of-concept that targeting multiple angiogen...... demonstrated the value of pharmacists in reducing adverse drug events in the hospital setting. One study showed that hospitals with pharmacists in patient care areas had a 45 percent decrease in medication errors overall and a 94 percent decrease in medication errors that adversely impacted patient outcomes...