Adverse housing conditions contribute to diabetes risk
...etes in this population. "But a counter-argument against that would be that diabetes risk was associated with housing but not neighborhoods," he says. "We would have expected that if stress was playing a role, the neighborhood conditions also would be involved." The researchers found that although there ...Drug for cluster headaches may cause heart problems
...ating pain of cluster headaches has to be balanced against the risk of causing a heart abnormality that could progress into a more serious problem, said study author Peter Goadsby, MD, PhD, DSc, of the National Hospital for Neurology and Neurosurgery in Queen Square, London, UK, and the University of Califor...MRI finds breast cancer before it becomes dangerous
...ot want the Bonn results to be used as an argument against current mammography screening programmes. 'Mammography is a basic examination that is essential for early detection.' MRI is not yet ready for use as a mass screening tool. 'Too little use is made of the method in the field of breast imaging, so corr...New study shows promise in reducing surgical risks associated with surgical bleeding
...ly 20 percent of these patients develop antibodies against bovine coagulation factors that can cross-react with human coagulation proteins and possibly lead to adverse effects, including severe bleeding and thrombosis. Due to these safety concerns, rhThrombin was developed as an alternative to bThrombin. ...Chromatin remodeling complex connected to DNA damage control
...as chromatin. "Chromatin creates barriers to DNA against anything that wants access to DNA, such as a transcription factor or DNA repair machinery," Shen says. "Chromatin remodeling shuffles the nucleosomes around to create access to DNA," Shen says. "This moving and sliding of the 'beads on the string' ...Pathway links inflammation, angiogenesis and breast cancer
...ressor used to protect organ transplant recipients against rejection of their new organs by suppressing mTOR. Rapamycin and similar mTOR inhibitors are in early clinical trials for a number of cancers at M. D. Anderson and elsewhere. One drug, temsirolimus, has been approved to treat renal cell carcinoma. ...Reductive stress linked to heart disease
...xidants are widely considered an important defense against heart disease, but University of Utah researchers have found excessive levels of one antioxidantreduced glutathioneactually may contribute to the disease. The findings, published in the Aug. 10 issue of Cell, indicate a new class of drugs can be de...Stanford researchers find culprit in aging muscles that heal poorly
...tion declines with age, and thus its effectiveness against Wnt decreases, allowing Wnt activity to pick up and disrupt the normal signaling to the stem cells in a variety of tissues studied. Rando said that, although the work of his team and the NIH researchers is different in terms of the techniques used ...NIH scientists target future pandemic strains of H5N1 avian influenza
...to contain a pandemic early on. Making a vaccine against an existing strain of H5N1 or any other type of in...nt in the vaccine and make neutralizing antibodies against them. Later, if that same person is naturally exposed to a flu virus, these same antibodies should h...UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
...resistant. Finding certain antibiotics ineffective against MRSA in a laboratory setting, however, does not necessarily mean they will fail in patients, who have the help of their immune systems. More research, including the study supported by this NIH contract, will address the impact of MRSA resistance to v...Despite claims, not all probiotics can treat diarrhea say experts
...cies, two of which have also been shown to protect against diarrhoea in chronically sick children. However, the lack of effect in children receiving Saccharomyces boulardii was unexpected, they say, because a previous trial showed it to be beneficial in young children admitted to hospital for diarrhoea. ...Preventive treatments in elderly people needs rethinking
...a wider perspective when balancing potential harms against putative benefits. We should not carry on extrapolating data from younger populations and using linear models that use absolute risks of disease rather than all cause mortality and morbidity. If we do, the only ones to benefit will be drug companie...Penn researchers discover novel pathway for increasing 'good' cholesterol
...terol transport, the process by which HDL protects against heart disease. Low levels of HDL-C put people at risk for atherosclerosis, thereby increasing the risk of heart attack and stroke. Although this study was performed in mice, humans have the same proprotein convertases and endothelial lipase, and th...Metabolic study in mice could lead to 'good cholesterol' boosters
...very could point the way to therapies that protect against heart disease by boosting concentrations of the beneficial high-density lipoprotein cholesterol (HDL-C). By and large, the medicines now available lower levels of the bad low-density lipoprotein cholesterol [LDL-C], said Weijun Jin of the Universit...UIC researchers to develop new drugs to fight bioterrorism
...f natural products for their therapeutic potential against anthrax and other infectious agents such as Y. pestis, F. tularensis, Brucella spp, and Burkholderia spp. Bauman will serve as director of the new center, with William Beck, professor and head of biopharmaceutical sciences, serving as deputy direct...Green tea holds promise as new treatment for inflammatory skin diseases
... In psoriasis, immune cells, which usually protect against infection, instead trigger the release of cytokines, which causes inflammation and the overproduction of skin cells. Other autoimmune diseases with similar side effects include lupus, which can lead to skin lesions, and dandruff. Green tea, alrea...Postpartum hospital discharges -- when is the 'right time?'
...me agreed upon minimum length of stay, he cautions against a one-size-fits-all approach to readiness. A customized reflection of both the mothers and her babys needs and concerns is required, Bernstein says. The length of postpartum stay is not the actual determinant of outcome, and the chronological clock...Heat-related deaths in middle, high school football players spikes in 2006
...d injury when tackled in a practice drill. Rules against spearing, or leading blocks and tackles with the helmet or face mask, have drastically reduced the number of direct injuries, Mueller said. The heat-related injuries warrant special attention because they are preventable, he said. These and other i...Mapping mountains from space with GOCE
...nges on one continent could be accurately measured against those on the other side of the world. Given the harsh and remote environments of many of the Earth's large mountain ranges such as the Himalayas or the Andes, an accurate map of the gravity field acquired from space will contribute significantly to g......re that is set to play a crucial role in the fight against climate change. The Centre for Innovation in Carbon Capture and Storage (CICCS) due to open in October 2007 will develop novel technologies to trap and store greenhouse gases permanently and safely, so they are not released into the atmosphere. ...