'Wrapping' Gleevec fights drug-resistant cancer
...the anti-cancer drug Gleevec is far more effective against a drug-resistant strain of cancer when the drug wr...aboratory studies, WBZ-7 was found to be effective against a form of gastrointestinal cancer that has developed a resistance to imatinib, the drug sold under t...Mayo Clinic research in cardiovascular disease presented at Experimental Biology 2007
...nner surface of blood vessels. It protects tissues against the formation of blood clots in arteries and veins. If the endothelium is not working properly, patients are at risk for developing heart disease, stroke, peripheral vascular disease and venous thrombosis. Normally, when EPCs move into the bloodstr...Biofeedback on abnormal mechanics lowers risk for stress fractures, pain under kneecap
...dmill showed the force of each footstrike measured against a line of what a normal, healthy footstrike should look like. The runners task was to constantly adjust the force with which each of their own feet hit the ground to keep it at or below the line on the screen. With this feedback, all runners imme...Resistant HIV quickly hides in infants' cells
...iretroviral agents for pediatric use, particularly against highly resistant infection. "There is also a need for new and widely accessible methods for detecting HIV infection in infants, whether resistant or not," he pointed out, "since transplacental transfer of maternal antibodies precludes the use of anti...Magnesium loss in patients given monoclonal antibodies
... even generalised convulsions. Furthermore, agents against EGFR are being used increasingly to treat solid tumours, in particular cancers of the colorectum. However, the extent of this side-effect in patients given these antibodies has not previously been fully assessed. Prof Sabine Tejpar and colleagues ...IDSA urges Congress to support Hatch amendments
...lp to protect patient safety and the public health against antimicrobial resistance. IDSA hopes that Congress will take this opportunity to act and the Society applauds Sen. Hatch for offering the Antibiotic Safety and Innovation amendment. ...New mechanism identified for resistance to targeted lung cancer drugs
...resistant tumors with combination therapy directed against both protein targets," adds Pasi A. Jnne, MD, PhD,...arget receptors of the ERBB family, which are used against breast cancer, colon cancer, head and neck cancer, and the brain tumor glioblastoma multiforme," say...Commonly used pain medications do not prevent Alzheimer's disease
...matory drugs (NSAIDs) may have a protective effect against Alzheimer's disease. The clinical trial, conducted at six dementia research clinics across the United States, involved more than 2,100 people over age 70 with no signs of dementia, but a family history of Alzheimer's disease. The participants were ...New treatment for fungus which causes thrush and sepsis
...eatments, liposomal amphotericin B and micafungin, against the common infections candidaemia and invasive can... add: "Micafungin also has broad-spectrum activity against Aspergillosis spp, thus to assess its efficacy in the treatment of invasive aspergillosis will be an...Drug company sales visits influenced doctors, study finds
...able to the researchers as the result of a lawsuit against Parke-Davis, the maker of gabapentin. The lawsuit was brought by a former employee who alleged that the company promoted gabapentin, which it sold under the name Neurontin, for uses not officially approved by the FDA. "To me, the remarkable thing i...Chronic family turmoil and other problems cause physical changes
...to look at how maternal responsiveness may protect against cumulative risk as well as the first, according to the researchers, to look at cardiovascular recovery from stress in children or youths. Evans said that the findings suggest that the physiological toll of coping with multiple risk factors is signifi...RAND study finds school playgrounds can help fight childhood obesity
...tic facilities can be important tools in the fight against childhood obesity, but many are locked and inacces...ts of policy intervention where gains in the fight against obesity could potentially be made." More research is needed, Scott said, noting that the study did...Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
... new paradigm for treating CF. Specific inhibitors against the enzyme, in conjunction with current antibiotic...he research team is to develop specific inhibitors against the bacterial SMase and test the idea in an animal model. ...Head and neck cancer vaccine targets proteins to create immune response
...n tumor cells to generate a strong immune response against cancer. However, developing these kinds of persona...response to strengthen the body's natural defenses against cancer and decrease the chance of cancer recurrence and the formation of secondary tumors. "The k...Research could lead to treatment for Alzheimer's disease
...l of our early designed compounds that were potent against memapsin 2 also inhibited memapsin 1," he said. "Selective inhibition of memapsin 2, or building selectivity, became very important. The scientific community was faced with a formidable challenge." Ghosh's team developed a novel structure-based des...Breastfeeding reduces risk of breast cancer for women who delay childbirth
...ant to note that breastfeeding provides protection against both estrogen and progesterone receptor positive a...ore the age of 25 and having many children protect against the type of breast cancers that express estrogen and progesterone receptors, these factors do not pr...Global Fund must fund salaries of health workers to deliver HIV, TB and malaria treatments
...ntries -- Mozambique and Malawi -- trying to fight against a full-blown AIDS epidemic with a fragile health system to underline the crucial role of Global Fund support to the health workforce. Mozambique, for example, estimates that in order to roll out HIV drug therapy across the country, it would need 8 he...Diet and lifestyle -- In the cancer fight, eating well is the best revenge
...coli and soy are believed to offer some protection against cancer, but how this occurs is not well-understood...tly show lifestyle factors that might help protect against this deadly cancer," she says. As part of a larger research project known as The Multiethnic Cohor...Groundbreaking principles on sexual orientation and human rights released
... "Yogyakarta Principles" call for worldwide action against violence, discrimination and abuse, by governments..., in 2006, 54 States called for the Council to act against egregious violations of the rights of lesbian, gay, bisexual, and transgender people. "States have......ese features can be detected. To protect soils against erosion risks and improve soil structure, the GAEC as applied in some countries, states farmers must establish an environmental cover for a buffer width, stipulated by the country itself (e.g. 5 metres), around waterways on all parcels adjacent to wa...