Albert Szent-Gyrgyi Prize for Progress in Cancer Research to Harvard's Harold F. Dvorak, M.D.
...nd instead continued to make large amounts of VPF, allowing malignant cells to continue to induce new blood vessels and so to grow and spread. Thus, tumors behave as wounds that fail to heal. This work is again extremely significant for patients worldwide, as Dr. Dvorak's scientific research is leading his co...No good evidence that cholesterol drugs lower melanoma risk
...ls from built-in "self-destruct" chemical signals, allowing them to grow out of control. Cholesterol-controlling statins and fibrates may slow or stop tumor growth or boost the anticancer effects of chemotherapy, Dellavalle and colleagues say. "Each statin has slightly different chemistry, but the distinction...RNA splicing occurs in nerve-cell dendrites
...communication between cells of the nervous system, allowing for many neurons to connect with each other to form a network. Dendrites detect the electrical and chemical signals transmitted to the neuron by the axons of other neurons. The synapse is the neuronal structure where this chemical connection is forme...Study reveals surprising attitudes about research involving adults with Alzheimer's
ANN ARBOR, Mich. -- How far will Americans go in allowing people with Alzheimer's disease to take part in studies of promising -- but sometimes risky -- new treatments and other research when they cannot consent for themselves? A new University of Michigan and University of Rochester study examines this iss...Young scientists turn to gel to ease side-effects of cancer treatment
...e Spectroscopy can be used as an imaging technique allowing the tumour to be identified accurately, because of the differing biological activity in tumour cells compared with healthy cells. A phantom is required to prove the accuracy of these measurements. The team has already supplied samples of the gels to ...Neurons generated in the adult brain learn to respond to novel stimuli
...integrate into other regions of the brain, perhaps allowing them to replace neurons lost to injury or disease....had been labeled to mark those that were dividing, allowing identification of newly generated, adult-born neurons. These mice were then exposed either to a pane...Journal of Rehabilitation Research & Development tipsheet
..., comfort with reading, and cosmesis (comfort with allowing others to see them read), and which spectacle magnifier they preferred. Volunteers' reading comprehension, satisfaction, and cosmesis were significantly better with the hybrid-diffractive lens than with the refractive aspheric lens. Although critical...International multi-center study confirms value of blood test to diagnose heart failure
...he study permitted more in-depth analysis of data, allowing the establishment of age-specific NT-proBNP levels defining a clear diagnosis of heart failure. The measurement below which heart failure could be ruled out was the same for all age groups. Analysis of the prospective value of NT-proBNP testing sho...Young cancer researchers honored
...se processes can be restored to cancer cells, thus allowing traditional chemotherapy drugs to destroy them. Another focus with his mouse model research is to gain insight into the genetic factors that influence the effectiveness of targeted therapies. "Our long-term goal is to use these models to determine ho...New blood test may improve risk assessment for ischemic stroke in middle aged adults
... improve identification of the high risk patients, allowing physicians to implement basic prevention strategies and potentially reduce the number of strokes that occur each year," said Richard B. Lanman, MD, Executive Vice President and Chief Medical Officer of diaDexus. "Additional analyses have shown that L...Radiation treatment prolonged liver cancer patients' lives, U-M study finds
...ry little of the drug travels throughout the body, allowing researchers to deliver a higher dose. Most often, ...fy the patients who are experiencing side effects, allowing the majority of patients who can handle higher doses of radiation to receive it - which would potent...Research findings contradict longstanding bias against morphine
...priate level of morphine can suppress this anxiety allowing a person to survive on less oxygen and live longer. It also allows these patients to live out their final minutes, hours or days of life in a more peaceful manner."...Large-scale study proves volunteer operated defibrillators are life-savers
...ttle, USA, initiated BEDS after Italy passed a law allowing the use of automated external defibrillators (AEDs) by non-medical personnel. A total of 2,186 volunteers and lay people received five hours of training involving theory and practical instruction, including training in basic life support, from 14 qua...Collapse of p53 into clumps might be linked to cancer, according to St. Jude
...he molecule p53 tends to destabilize this protein, allowing it to form potentially disease-causing aggregates, or "clumps," according to a study by investigators at St. Jude Children's Research Hospital. The mutation that causes clumps to form is associated only with the pediatric cancer adrenocortical carc...Disruption of gene interaction linked to schizophrenia
...tation may worsen the symptoms of schizophrenia by allowing dopamine levels to rise." The prefrontal cortex is the part of the brain involved in complex cognitive functioning (e.g., thinking and reasoning). In the same issue of Nature Neuroscience, another group of investigators reports that their study of a...Specialized neurons allow the brain to focus on novel sounds
... unimportant sounds from reaching the cortex, thus allowing people to ignore sounds that do not require attention. "It is probably a good thing to have this ability because it allows us to tune out background noises like the humming of a car's motor while we are driving or the regular tick-tock of a clock," C...Memory formation follows a dynamic pattern, allowing for retrieval from different areas of the brain, depending on when an organism needs to remember, said a researcher at Baylor College of Medicine. That is what Dr. Ron L. Davis, professor of molecular and cellular biology at BCM, theorizes, based on ...Scientists directly view immune cells interacting to avert autoimmunity
...us deep within the lymph node of a diabetic mouse, allowing the researchers to show that immune cells known as T regulatory, or Treg, cells control the destructive action of rogue autoimmune cells when each of the two cell types interact with a third kind of cell. The role of the third cell type -- the antige...Modified Atkins diet effectively treats childhood seizures
...or some children, we need not be so restrictive in allowing protein, weighing foods and counting calories. That should make it a little easier for parents and children to do." The Hopkins study examined 20 children (ages 3 to 18) who were having between 4 and 470 seizures a week and whose illness was unrespon...New treatment for pancreatic cancer allows life-saving surgery
...ause the treatment Pipas and his team developed is allowing more patients the option of surgery, it is now the standard treatment for pancreatic cancer at the Norris Cotton Cancer Center. In a new study, Pipas is using gemcitabine and radiation in combination with cetuximab (Erbitux), an antibody treatment....