Engineered blood vessels may be an option in cardiac bypass
...ty and clot resistance of the vessels in different animal models," McAllister said. "Now, we're reporting for the first time our results in humans. We are presenting results on the first three of nine participants in a study looking at the use of engineered blood vessels in hemodialysis patients. The maj...Statins may simulate stem cells for heart repair
...ved cardiac function and coronary blood flow in an animal model in which flow had been artificially restrict... repair damaged heart tissue," Suzuki said. "Many animal and early clinical studies using this source of stem cells are ongoing right now." Earlier reports ...Drug may fight lupus and atherosclerosis simultaneously
...ndings represent a merger of two lines of Mishra's animal research using TSA one showing that the drug reduced lupus symptoms, especially inflammation of the kidneys and enlarged spleens, and the other showing that TSA was effective against atherosclerosis. Mishra was joined in the atherosclerosis research...Common anti-seizure drug could be effective for lupus patients
...ain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine. The drug, valproic acid (Depakote), prevents skin disease and reduces the severity of kidney disease in a mouse model of lupus, said Nilamadhab Mishra, M.D., a rheumatologist at Wake Forest Univ...Jefferson researchers find drug may give some cardiac protection 24 hours after heart attack
...t the time of simulated heart attack in an another animal model, and found it protected the animals. But in further studies, Dr. Koch gave Darbepoietin to animals at the time of ischemia and heart attack, one to two hours after, and 24 hours later. In each case, the scientists saw that the drug offered si...Some foods and beverages could hold clues for future diabetes treatment
...e with diabetes. In early laboratory studies using animal pancreatic cells, the chemicals, called anthocyanins, increased insulin production by 50 percent, according to study leader Muralee Nair, Ph.D., a natural products chemist at Michigan State University in East Lansing. But you might want to limit the ...New gene silencing therapy for cervical cancer
...etely eliminate the formation of cancer tumours in animal models," Dr McMillan said. Professor Ian Frazer, Director of the CICR and developer of a vaccine for cervical cancer, said the research represented a significant step towards developing gene therapy for cervical cancer. Cervical cancer is the leadi...New vaccine platform may fight infections with causes from influenza to bioterrorism
...e we'll need to replicate these findings in larger animal models, our studies indicate it may be feasible to develop vaccines for bioterrorism agents and transplant patients, as well as high-risk individuals who have defective CD4+ T-cell function," Dr. Kolls said. "We are excited about the results because ...Stanford study of sea squirt provides clue to human immune system
...gin with the vertebrate immune system, far back in animal evolution, potentially shedding light on the devel...ble philosophy is Botryllus schlosseri, a colonial animal that looks deceptively like a small flower. Each of its apparent petals is actually a separate, thou...Time is right for vets and doctors to debate food policy
...is linked to reduced human health and reduced farm animal welfare, both of which are important matters of pu... now tend to associate good human health with good animal welfare, and the health professions are being asked to encourage a dramatic shift in national diets....Problem of emerging infectious diseases likely to worsen
...ectious diseases pose a global threat to human and animal health, and the problem is likely to worsen, warns...problem for human health but are a major threat to animal welfare and to species conservation. Some emerging infectious diseases also threaten domesticated sp...Over-the-counter arthritis drug might also help against MS, Jefferson neuroscientists find
...nervous system. Dr. Rostami and his group used an animal model of MS called experimental autoimmune encephalomyelitis (EAE), which mimics the human disease, to investigate glucosamine's potential immune system-suppressing properties. Such animals gradually develop the disease. In the studies, some of the ...Agricultural workers at increased risk for infection with animal flu viruses
...virus has not appeared in the United States in any animal population or in humans....Report shows steep rise in support for health charities that don't fund animal tests
...ealth charities that have a policy against funding animal experiments, according to a new report released to...sed for innovative non-animal research rather than animal experiments. Support for humane giving is growing faster in older populations. In 1996, young peopl...Hormone aldosterone is promising target for stroke treatment
... hormone does and what blocking it prevents. In an animal model of stroke and hypertension, Dr. Dorrance and... vessels look like a normotensive animal, like the animal never had high blood pressure," says Dr. Dorrance. "But when you block aldosterone in the females, t...Hair follicle stem cells contribute to wound healing
...rsity of Pennsylvania School of Medicine. Using an animal model, the researchers discovered that stem cells in the hair follicle are enlisted to help heal wounds in the skin. This finding, published online in Nature Medicine last week, may suggest a therapeutic target for the development of drugs to encoura...Hopkins study proves cochlear implants prevent or reverse damage to brain's auditory nerve system
...nts will evaluate brain changes that occur when an animal grows up in an environment that is devoid of sound, which the scientists believe will guide future therapies in restoring useful hearing to the deaf....JCI table of contents: December 1, 2005
...rient availability; (ii) that the age at which the animal is exposed to a high-fat diet plays a factor in the development of obesity; and (iii) the existence of a gender difference in body weight homeostasis in response to GSHR deficiency. Sleeman and colleagues suggest that during the early post-weaning pe...Debilitating jaw and neck pain targeted through $19 million NIH support, multidisciplinary center
...e also used molecular biological, cell culture and animal behavior experiments to show a relationship between variations in the gene that makes COMT, COMT enzyme activity and pain sensitivity. This was the first demonstration that a genetic variation influences both human pain perception and the risk for de......tic plaque in blood vessels. According to a recent animal study of a new gene therapy, a single injection led to a significant reduction in plaque and moderation of an immune response that contributes to plaque buildup and rupture. Another study found that the administration of certain antibodies significan...