Can rice bran oil melt away cholesterol?
...ournal. They show that total cholesterol levels in animals dropped by 42 percent, and LDL or "bad cholesterol...n, Minhajuddin and colleagues previously showed in animals that TRF reacts with liver enzymes in such a way that it clears toxic substances from the organ, and...Researchers prevent post-traumatic brain damage
... in this study, they delivered flavopiridol to the animals 30 minutes after brain injury and found that it reduced expression of proteins that activated the cell cycle, thus limiting growth of the glial scar and formation of an inflammatory response. The size of the lesion was reduced by more than 80 percen...Cutting-edge technologies signify a new era for colorectal cancer screening
... No significant adverse events were detected. All animals were in good condition at 24 hours and seven days post-procedure. "Preliminary studies which supplied the proof of concept in humans as well as the study presented here suggest that this technology could provide a reliable, less invasive, sedation-...As morphine turns 200, drug that blocks its side effects reveals new secrets
...s continued to develop the compound, testing it in animals and performing the initial human safety trials and clinical studies in volunteers and patients. The University of Chicago licensed the MNTX technology to UR Labs, Inc. and in 2001, Progenics Pharmaceuticals of Tarrytown, NY, sub-licensed the worldw...Biomarkers for interstitial cystitis identified, could lead to the first test
...und three nuclear proteins that were unique to the animals with IC. Using protein mass fingerprinting, the proteins were identified as transgelin (SM-22), ras suppressor protein (RSU-1) and GAPDH. In the second study, titled "Time-point study of the Regulation of Nuclear Protein SM-22 (Transgelin) in the Rat...Federal NIH office clears Ohio State research program
... had adequately searched for alternatives to using animals in the project. Through a series of letters betwee...y group at Ohio State responsible for safeguarding animals used in research. "Based on its assessment of this explanation, OLAW finds the ILACUC review and the...Steroid-free regimen with CellCept found comparable to standard therapy in liver transplantation
...til) has been shown to have teratogenic effects in animals at subclinical doses on a body surface area basis, it may cause fetal harm when administered to a pregnant woman. CellCept should not be used in pregnant women unless the potential benefit justifies the potential risk to the fetus. Women of childbe...Tiny bundles seek and destroy breast cancer cells
...mice treated with "empty" liposomes. The weight of animals treated with ceramide did not vary significantly from the mice treated with empty liposomes signifying that the ceramide was not toxic (weight would have been lower with toxicity). When the tumors were examined, those treated with ceramide showed a 2...Laughter-induced asthma: It's no joke
... it's even more common than dust mites, allergy to animals and molds," he said. "It's a little-appreciated frequent trigger." The study found that the most common symptom in patients with laughter-induced asthma was coughing, which generally starts within two minutes. The next most common symptom was chest t...High blood pressure causes pathological scars in the heart
...the research team has provided evidence, from both animals and high blood pressure human patients that this hypothesis was, indeed, correct and proceeded to explore some possible mechanisms for this deterioration. Researchers at CIMA and the Navarre University Hospital have developed a method for the bloodl...Personalized immunosuppression with leading organ transplant therapy may optimize patient care
...til) has been shown to have teratogenic effects in animals at subclinical doses on a body surface area basis, it may cause fetal harm when administered to a pregnant woman. CellCept should not be used in pregnant women unless the potential benefit justifies the potential risk to the fetus. Women of childbe...In those genetically predisposed, 'developmental reprogramming' could explain cancer risk
...develop the tumors as an adult, and a set of these animals were used as a "control" group. For the experiment...loped tumors by 16 months. "The DNA of DES-exposed animals had been modified by DES in a way that changed how genes responded to estrogen, causing this tissue ...Stress may increase long-term success of vaccinations
...sponses than non-stressed mice when both groups of animals were re-exposed to the same antigen several months...d pathogens. The fact that the previously stressed animals had thicker earlobes a result of the elevated levels of immune cells responding to KLH suggests th...Tercica presents pharmacokinetic and safety data from several studies at Endocrine Society Meeting
...tment; and a life-time rhIGF-1 toxicology study in animals thatdemonstrated a reduction in the incidence of some endocrine cancers. Thesedata provide further insight into the long-term safety of rhIGF-1 treatment. "These pharmacokinetic and safety studies indicate the depth of dataincluded in our New Drug Ap...3D atlas will help navigate the spinal cord
...considerations and relate data from experiments in animals back to humans. The proposed description of the structure of the spinal cord will be based on a comprehensive use of neurochemical markers (chemoarchitecture). Many pathways in the nervous system contain a particular protein which can be demonstrate...New memory drug works best in combination with older remedy
...ith memory formation. "The findings in laboratory animals both improved memory in our tests and evidence that the drug targets the biology for making memories in the brain places this drug on solid footing as a candidate therapeutic agent," said the study's lead author, Michela Gallagher. SGS742, previous...Mayo collaboration: Discovery blocks breast cancer growth, stimulates immunity
...: significantly delayed the growth of tumors in animals with early stage, minimal tumors. slowed the growth of tumors in both early stage and late stage tumor groups. reduced mean tumor sizes as compared to controls. In the minimally diseased group, tumors were 90 percent smaller, and in the late-stag...Social support linked to prognostic marker for ovarian cancer
...disease. Previous studies in humans and laboratory animals have shown IL-6 levels are also influenced by behavioral factors. IL-6 has previously been shown to promote tumor growth, and IL-6 levels are also prognostic in ovarian cancer, with elevated levels associated with higher mortality and metastatic dise...The promise of a tetracycline antibiotic for treating osteoarthritis
... actions as a drug and, in laboratory studies with animals and with human tissue, can inhibit the degradation of cartilage in a way that could be useful for the treatment of osteoarthritis (OA). OA is a common form of arthritis associated with pain and disability related to the breakdown of cartilage, the ti...4D proton therapy, radiation-resistant tumors, interpreting medical images
...to form images of the oxygen distribution of small animals with millimeter spatial resolution. Developing these tools at the Center for In-Vivo EPR Imaging directed by Howard Halpern at the University of Chicago, the researchers create these important maps of oxygen levels by magnetically manipulating the ...