Tag: "antibody" at medical news
...o the development of Rituxan, the first monoclonal antibody
approved to treat cancer. Dr. Levy's talk will be "Immunology: From science to therapy." V. Craig Jordan, Ph.D., D.Sc. , Vice President and Scientific Director of the Medical Science Division of the Fox Chase Cancer Center, Philadelphia, Pa. Dr. Jor...
NIAID begins clinical trial of West Nile virus vaccine
...he DNA vaccine's exploitation of both cellular and antibody
immunity offers a potentially potent defense against West Nile virus," says Barney Graham, M.D., Ph.D., chief of the VRC's Clinical Trials Core Laboratory. Adds Dr. Graham, "In our experience in clinical trials, DNA vaccines generally cause few side ...
CML found to wield 'death factor' that kills normal blood marrow cells
...ow in this study that blocking the protein with an antibody
in mouse cell experiments will restrain the ability of the cell death protein to kill normal bone marrow cells, the researchers suggest that a therapy that could disable 24p3 might prove useful to CML patients when combined with traditional treatment...
Monoclonal antibody cures West Nile virus-infected mice
...is, April 24, 2005 -- A newly developed monoclonal antibody
can cure mice infected with the West Nile virus, s...successful demonstration of the use of a humanized antibody
as a post-exposure therapy against a viral disease," says senior investigator Michael Diamond, M.D.,...
Promising new West Nile therapy cures disease in mice
... The research team developed an infection-fighting antibody
that mimics one produced by people whose immune sy... the West Nile virus. The researchers tested their antibody
in mice and say its success warrants further development and testing in people with West Nile diseas...
American Academy of Neurology sums up scientific highlights from 57th annual meeting
... be reduced in mice by treatment with a monoclonal antibody
to the prion. Further development of this strategy may also offer hope for treatment of these diseases. [P04.149] Cancer Temozolomide chemotherapy plus radiation is superior to radiation alone in treatment of glioblastoma multiforme, a type of brai...
UT Southwestern lead site for study of a new multiple sclerosis drug
...hers are testing Rituxan a therapeutic monoclonal antibody
approved by the Food and Drug Administration in 1997 for treating some forms of cancer. "It's an exciting study and the patients are really enthusiastic about this," Dr. Hawker said. The primary progressive form of MS is characterized by a slow, ste...
UQ develops West Nile virus treatment
...py treatment for the disease based on a monoclonal antibody
that binds to the benign Australian Kunjin virus. The treatment completely neutralised the West Nile virus and provided infected mice protection against the onset of symptoms, according to Dr Hall. "We also believe it may be possible to reverse the...
New insights into HIV immunity suggest alternative approach to vaccines
...lop ways to induce that first line of polyspecific antibody
defense during vaccination, if these antibodies are not harmful to those being vaccinated," Haynes said. "We now have a window into how to study HIV vaccines from the host side of the problem," he said. Collaborators on the study include Judith Flemi...
Jefferson scientists create plant factories churning out antibodies against tumor cells
...ferson Medical College, inserted DNA coding for an antibody
against colorectal cancer into tobacco plants. The...ts. But the technology to produce large amounts of antibody
is expensive, and researchers would like to find alternatives. Dr. Koprowski, Dr. Ko and their co-wo...
FDA approves Boostrix a new US vaccine for adolescents against pertussis
...dition, the use of Boostrix induced anti-pertussis antibody
levels which were non inferior to those observed i... compared to Infanrix, the ratio of geometric mean antibody
levels to pertussis antigens following the use of Boostrix ranged from 1.9 to 7.3. In this observer-...
Scientists report strong evidence of alterations in blood samples of children with autism
...other metabolites in children with autism: The antibody
producing B cells are increased by 20 percent in the autism group Natural killer cells are increased by 40 percent More than 100 proteins demonstrated significant differential expression between the autism and typically developing groups Other sm...
Active vaccine prevents mice from developing prion disease
...mmune response to the gut and mainly stimulates an antibody
response, says Dr. Wisniewski. "By giving our vaccine orally, we're stimulating an immune response mainly in the digestive tract," he explains. "Thus, harmful prions in contaminated food will be destroyed in the gut and will not reach other organs in...
Study finds maternal exposure to parasitic infection may increase risk of schizophrenia in offspring
...al link between high maternal toxoplasmosis gondii antibody
titers and development of schizophrenia spectrum d... offspring. No association was found for moderate antibody
titers. While active toxoplasmosis infection is known to adversely affect fetal brain development, ...
Targeted cancer drug combined with low-dose chemotherapy shrinks tumors, slows ovarian cancer
...b is the common name for Avastin TM , a monoclonal antibody
that targets and stalls the function of a substanc...y results may lead to a new use of this monoclonal antibody
in the treatment of ovarian cancer." Ovarian cancer is the seventh most common cancer among women a...
Antibody combined with cancer drug shows promise against breast tumors
DALLAS May 15, 2005 An antibody
that targets the blood vessels nourishing tumors s...appears in today's issue of Cancer Research. "This antibody
could enhance the therapeutic efficacy of the drug docetaxel in breast cancer patients," said Dr. Ph...
Biologic therapies for bowel disease show promise in clinical trials
...months. Adalimumab is a fully human monoclonal antibody
that targets tumor necrosis factor-alpha (TFN-a), a protein produced by the body's immune system that is thought to contribute to the inflammation in Crohn's disease and ulcerative colitis. A total of 220 patients participated in the study, receivin...
Study shows Erbitux may fight colorectal cancer after other therapies fail
...bundance on the surface of a cancer cell. Once the antibody
is attached, it blocks substances called epidermal growth factors (EGF) from fitting into the receptors. EGF gives orders for a cancerous cell to grow, so blocking EGF interferes with growth. Most colorectal cancers express EGFR, and high levels of ...
Researchers find way to streamline new non-Hodgkin's lymphoma treatment
... attack, physicians infuse rituximab, a monoclonal antibody
that hones in on B cells, the immune cell most often involved in non-Hodgkin's lymphoma. Next, for the imaging sessions, physicians inject another monoclonal antibody, ibritumomab tiuxetan, which is specially tagged with a radioisotope known as indiu...
Zevalin safe and effective for non-Hogdkin's lymphoma patients with advanced disease
... (ibritumomab tiuxetan), a radiolabeled monoclonal antibody
that targets radiation directly to a tumor. The st...ond safely to treatment with Zevalin. A monoclonal antibody
linked to the radioisotope, yttrium-90, Zevalin targets the CD20 antigen on the surface of mature B ...
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