It's in the genes: Study opens door to new treatment of the blues
...ve made great progress in our understanding of how antidepressants work, but despite years of research, our knowledge of the changes that these drugs induce in the brain is rudimentary," Bolanos said. "Though available treatments for depression are generally safe and effective, they are still not ideal. It takes lon...How 'hot' emotional brain interferes with 'cool' processing
...e kinds of studies to determine whether particular antidepressants influence the response of that ventral system. And what is particularly exciting is that this method allows us to look directly at the neurological target of the drug and not have to try to measure the more nebulous behavioral response. So, we can de...Anti-depressant use associated with increased risk for heart patients
...hysicians caring for heart patients who are taking antidepressants should monitor patients closely. Watkins added th...e antidepressants, particularly the newer class of antidepressants known as selective serotonin reuptake inhibitors (SSRI), have been generally considered safe," Watki...Faxed alerts to physicians may not improve patient antidepressant adherence
...ir patients fail to refill their prescriptions for antidepressants may not increase the rates of patients taking thei...ess than half (6,387) of the patients began taking antidepressants before the fax alert program began and slightly more than half (6,741) began afterward. Over the tw...Long-term antidepressant therapy best treatment for depression in old age
...ode of depression than those who continued to take antidepressants for two years," said Charles F. Reynolds III, M.D., UPMC Professor of Geriatric Psychiatry, University of Pittsburgh School of Medicine, and principal investigator of the study. "By continuing antidepressant therapy for two years, we were able to red...Antidepressants might reduce risk of colorectal cancer
Use of some antidepressants might reduce the risk of developing colorectal can...ing in the April issue of The Lancet Oncology. The antidepressants known as selective serotonin reuptake inhibitors (SSRI) "might inhibit the growth of colorectal tumo...Antidepressant drug may prevent recurrence of depression in patients with diabetes
... Although they knew that short-term treatment with antidepressants was helpful with mood and with control of blood glucose, Lustman's team didn't know whether the drug could prevent the recurrence of depression in patients with diabetes. He also didn't know what would happen to glucose levels in the months following...Study identifies predictors of bipolar disorder risk
...ts potentially making the illness harder to treat; antidepressants alone have been shown to induce mania or hypomania (a mild form of mania) in some patients with bipolar depression. Furthermore, people with untreated bipolar disorder can experience a greater frequency of manic and depressive episodes, causing sign...ST. John's Wort relieves bladder pain in animal models
...oms of mild depression, while urologists often use antidepressants to treat interstitial cystitis," said Michael B. Chancellor, M.D., professor of urology and gynecology at the University of Pittsburgh School of Medicine. "Given that the supplement and the drug work on the same systems, it makes sense that St. John'...Transporter is possible target for safer pain medicine
...ctive, but by a different mechanism." Many popular antidepressants work in a similar fashion to keep the body's natural chemical messengers, called neurotransmitters, working longer by keeping them from being taken back up into the neuron by transport systems. Chemical messengers are supposed to have limited action,...New study suggests antidepressants save lives
...just published UCLA study suggests that the use of antidepressants to treat depression has saved thousands of lives, ...adults. A key unanswered question involves whether antidepressants increase suicide over and above the underlying disorder, such as major depression. "Much of the psyc...US suicide rates fell as fluoxetine prescriptions increased
...in suicide. "Although the current issue concerning antidepressants and suicidality requires further examination," the...e and colleagues cannot prove for certain "whether antidepressants do harm or good at a population level." Nevertheless, they say that the study "does not support an ...REM sleep behavior disorder at young age linked to antidepressant use
...ished study have suggested the association between antidepressants and RBD, this study represents the first systemati... mean one of three things: 1) in younger patients, antidepressants can cause RBD, or 2) in younger patients, RBD results in psychiatric diagnoses that then result in a...Mild sadness provokes depressive thinking in some recovered patients
...y to predict relapse. In addition, those who took antidepressants were more likely to have greater cognitive reactivity than those in the cognitive behavioral therapy group. "Our study indicates that even a mild negative mood, when experienced by someone with a history of depression, can reinstate some of the co...UGA researchers find high rates of off-label prescriptions
...rs said the high rate of off-label prescribing for antidepressants likely stems from the high degree of overlap in symptoms among various mental illnesses. The high rates of off-label prescribing of powerful antipsychotic and anticonvulsant drugs for the elderly underscores the lack of effective treatments for Alzhe...Children and teens taking antidepressants might be more likely to attempt, complete suicide
...dal behavior among children and teens treated with antidepressants after a large analysis of clinical trials revealed...her there is an association between treatment with antidepressants and suicidal behavior in adults, according to background information in the article. Because relati...Study suggests anesthetic agent may have rapid antidepressant effects
...g that they were unsuccessfully treated with other antidepressants at least twice. After a two-week drug-free period...urred during the study. Most currently available antidepressants work by increasing the levels of chemicals in the brain known as monoamines, including serotonin and...Experimental medication kicks depression in hours instead of weeks
...umans and animals, in a preliminary study. Current antidepressants routinely take eight weeks or more to exert their ...strate the importance of developing new classes of antidepressants that are not simply variations of existing medications." For this study 18 treatment-resistant, dep...Carnegie Mellon, Ohio State get grant to study link between antidepressants and suicidality in teens
...e of Mental Health to investigate the link between antidepressants and suicidality -- including suicidal thoughts, at...Food and Drug Administration's (FDA) findings that antidepressants are causally linked to an increase in suicidal thoughts and behaviors in young people. In 2004, th...Bipolar disorder exacts twice depression's toll in workplace
... as major depressive disorder," noted Wang. "Since antidepressants can trigger the onset of mania, workplace programs...cent of the depressed patients were already taking antidepressants when they began the study and still met clinical criteria for depression and that job performance c...