Your heart could indicate whether you have kidney problems
May 12, 2005 - Cardiovascular risk factors appear to indicate deteriorating renal function in all adults. Researchers discovered various indicators of heart or vascular disease can signal that kidney function is on the decline in the general population, as published in the May issue of Kidney Intern...Substantial 15-year survival gains from standard breast cancer treatments
... cancer, surgery (or surgery and radiotherapy) can appear to remove all traces of the disease, but undetecte... decades will benefit." (Quote by e-mail; does not appear in published paper) In an accompanying comment Karen Gelmon (British Columbia Cancer Agency, Vancouv...High overnight blood pressure linked to increased blood sugar levels
...portant that we monitor these levels in people who appear to be at higher risk, such as people whose blood pressure does not drop significantly overnight," Supiano says....Mount Sinai study shows Hispanics have worse lung cancer survival rate
... larger group of white persons. Study results will appear in the second issue for May 2005 of the American Thoracic Society's peer-reviewed American Journal of Respiratory and Critical Care Medicine. Juan P. Wisnivesky, M.D., M.P.H., of the Department of Medicine at Mount Sinai School of Medicine in New Yo...Mayo Clinic researchers report on effectiveness of treatments for hot flashes
...with hot flashes. Researchers say that hot flashes appear to be triggered by changes in a woman's brain chemistry that result from decreased estrogen levels as she approaches menopause. There are other non-estrogenic treatments for hot flashes that researchers have identified that do work. Women and their p...New test for early detection of prostate cancer shows promise
...te-specific antigen (PSA) testing. Study results appear in the May 15, 2005, issue of Cancer Research. The lead author is Robert H. Getzenberg, Ph.D., professor of urology and director of research at the James Buchanan Brady Urological Institute at Johns Hopkins. The traditional two-step approach of PSA t...Popular procedures evaluated for diagnostic accuracy and treatment effectiveness
...e sham procedure. The EndoCinch procedure did not appear to reduce exposure to acid in the esophagus compared to the sham procedure. "Endoscopic sutures are growing in popularity and our study confirmed that the procedure can indeed reduce GERD symptoms and the need for acid-reducing medications," said Mat...Investigating the appropriateness of current alcohol-use disorder criteria for adolescents
... spent' using, and using more/longer than intended appear to often be over diagnosed in adolescent studies; two, that the ways in which these dependence criteria are measured has a huge downstream impact on the estimated prevalence of abuse and dependence diagnoses; and three, that certain AUD criteria may ...Neuroimaging confirms the greater vulnerability of women's brains to alcohol
Women appear to be more vulnerable to chronic drinking than men...elated brain damage more readily than men. Women appear to be more vulnerable to chronic drinking than men are. Yet few studies have looked at gender diffe...New preoperative chemotherapy and radiation regimen yields encouraging results for sarcoma
...ffect otherwise healthy young people. Tumors often appear as masses on the legs or arms, but also include gastrointestinal stromal tumors, pediatric sarcomas, and sarcomas of the uterus. "Soft-tissue sarcoma tumors are varied and often complicated, so multidisciplinary care by an experienced sarcoma team...Vitamin D, taxotere combination promising for advanced prostate cancer
...cts receiving DN-101 in combination with docetaxel appear to have a 49 percent increase in survival versus subjects taking docetaxel alone. "The overall goal of the study was to confirm results from a small phase II OHSU study and to determine if this combination should be developed as a new treatment f...Combined MRI and mammography more effective at detecting breast cancer in high-risk women
...rs of BRCA1 mutations." (Quote by e-mail; does not appear in published paper) In an accompanying Comment Ellen Warner (Toronto-Sunnybrook Regional Cancer Centre, Ontario, Canada) points out: "Although there is now unequivocal evidence that surveillance MRI is significantly more sensitive than mammography f...Mayo Clinic: Biomarker that may improve quality of life during treatment for colorectal cancer
...ch indicates that there is a group of patients who appear to have, based on genetic differences in an enzyme, a lower threshold to the toxic side effects of oxaliplatin. If our finding is confirmed in a second trial, this could be of great clinical importance because it would enable those patients with a ge...New class of drugs may treat lung tumors resistant to Iressa and Tarceva
...apy drugs like Iressa and Tarceva. In a report to appear in Proceedings of the National Academy of Science, researchers from Massachusetts General Hospital (MGH) Cancer Center and colleagues from Wyeth Pharmaceuticals research division describe finding how drugs called irreversible EGFR inhibitors apparent...Biologic therapies for bowel disease show promise in clinical trials
... 1). "Given that anti-TNF agents like infliximab appear to be effective in treating Crohn's disease, it made sense to explore its use in ulcerative colitis as well," said Dr. William Sandborn of the Mayo Clinic and lead investigator of the ACT II trial. "I am pleased to say that the ACT I and ACT II resu...Study shows Erbitux may fight colorectal cancer after other therapies fail
... epidermal growth factor receptors (EGFR) that may appear in abundance on the surface of a cancer cell. Once the antibody is attached, it blocks substances called epidermal growth factors (EGF) from fitting into the receptors. EGF gives orders for a cancerous cell to grow, so blocking EGF interferes with gr...Over-feeding in infancy might set the stage for childhood obesity
...rnal influences on infant body composition may not appear initially as obvious physical differences during the first six months of life". This is in line with previous studies, which showed that obesity doesn't manifest itself until 2 years of age....Nutrition gene key in regulating immune system
...uts T cells to sleep. "Whatever it's doing doesn't appear to be killing the T cells. It would be nice to be able to mimic the effect of IDO by using a drug that activates this pathway." Now that they have a knockout, comparative studies with regular mice can determine other genes that might be impacted down...Several factors can increase risk for recurrent blood clot
...e who did not. "Solitary laboratory abnormalities appear not to predict the risk of recurrence. Therefore, extensive, if any, thrombophilic work-up after a first thrombotic event is not likely to confer a clinical benefit to the patient. Similarly, a differential treatment with regard to duration of oral a...Iodine deficiency, supplements affect thyroid cancer risk in children exposed to radioactive iodine
...tantly, both iodine deficiency and supplementation appear to modify this risk, according to a new study in t..."Both iodine deficiency and iodine supplementation appear to be important and independent modifiers of the risk of thyroid cancer after exposure to I-131 in c...