Immune system lab model overcomes ethical limits on human hematopoietic stem cells studies
...tools for studying the human immune system." Other authors of the study include Leonard D. Shultz, Bonnie L. Lyons, Lisa M. Burzenski and Bruce Gott (The Jackson Laboratory, Bar Harbor, ME); Xiaohua Chen and Stanley Chaleff (St. Jude); Malak Kotb (University of Tennessee, Memphis); Stephen D. Gillies (EMD Le...Combination treatment improves survival for pancreatic cancer
... have a detrimental effect on quality of life. The authors state, however, that a larger confirmatory trial may be needed before this combination regimen could be regarded as the new standard treatment. Dr Reni states: "We have shown that patients allocated PEGF had a more favourable outcome in terms of prog...Low-fat dairy may lower risk of type 2 diabetes in men
...ited States and 135 million people worldwide," the authors provide as background information. "Because manag...ntake, may lower the risk of type 2 diabetes," the authors state. (Arch Intern Med. 2005;165:997-1003. Available post-embargo at www.archinternmed.com ) Edit...Regular vigorous physical activity could slow progression of prostate cancer
...gh-grade, advanced, or fatal prostate cancer," the authors write. "Although the mechanisms still need to be understood, these findings suggest that vigorous activity could slow the progression of prostate cancer and might be recommended to reduce mortality from prostate cancer, particularly given the many ot...Atorvastatin shows promise in small trial for the treatment of mild to moderate Alzheimer's disease
... behavior anticipated in mild to moderate AD," the authors write. "As a pilot proof-of-concept study, signifi...pt trial with a small number of participants," the authors conclude. "We believe that we provide evidence for proof of concept, and establishment of similar be...Older adults with diabetes in managed care networks have higher rates of untreated eye disease
...der persons with diabetes may not be adequate. The authors suggest that managed care has the potential to enh...er rates of diabetic retinopathy and glaucoma, the authors report. Overall, managed care patients were more likely to have at least one of the three eye diseas...US Latinos may develop Alzheimer's disease symptoms at earlier age than white, non-Latinos
...individuals with a similar educational level," the authors conclude. "The factors responsible for this remain to be identified, but the observation has a potential impact on both the burden of dementia care carried by this population group and the dementia-related diagnostic and educational efforts directed ...Misunderstanding real cost a barrier to mammography
...might help offset any financial burden. The study authors concluded that mammography screening campaigns may...iliar with details of their policies." Though the authors say it would be inappropriate to conclude from this study alone that an educational campaign would h...Untreated low-grade ductal carcinoma in situ poses long-term risk
... and died within seven years of IBC diagnosis. The authors conclude, "Even low-grade DCIS, left without further treatment, predicts for a regional risk and will eventuate in invasive carcinoma in the same site in the same breast in 30 percent of cases within 15 years." ...Poor understanding of coverage deters breast cancer screening
...r insurance coverage of screening mammography. The authors conclude that "these results suggest that improving women's knowledge about the actual out-of-pocket costs and insurance coverage for screening mammograms may reduce the overall impact of cost as a barrier."...News tips from the journal of Neuroscience
...t from the injury site. Using a 42 d protocol, the authors differentiated the H7 hESC line into OPCs. They then transplanted the oligodendrocyte progenitor cell (OPCs) into the site of a contusion injury that caused moderate hindlimb motor impairment. Cells transplanted at 7 d or 10 months after injury survi...Fragile US vaccine system needs improvement despite dramatic gains in health over past century
...is fragile and needs significant improvements, the authors report. Since 2000, vaccines against nine of the twelve vaccine-preventable diseases of childhood have been in short supply. As of 2004 only four commercial companies produce vaccines for young children, and vaccines for seven of the preventable di...Children with high blood lead levels often do not receive follow-up tests
... essential component of secondary prevention," the authors write. "To maximize cognitive development in these children, it is crucial to improve follow-up and to understand and develop interventions to overcome these unexpected disparities in care." (JAMA. 2005; 293: 2232 2237. Available post-embargo at ...Lag-time often occurs before new treatments for pediatric HIV infection are used
...ed to a shorter time to first regimen switch," the authors write. "Monitoring and documenting ART use in HIV-infected children can provide important insight regarding the clinical care of this population."...Earlier treatment of perinatal HIV associated with decreased HIV progression, better outcomes
...during or near the time of primary infection," the authors write. (JAMA. 2005;293:2221-2231. Available post-embargo at JAMA.com ) Editor's Note: This study is supported by funding from the Office of AIDS, California Department of Health Services. Editorial: Balancing the Upside and Downside of Antiretrovir...Hyperhidrosis and its treatment becoming better understood
...nt and minimizing its adverse effects, Mayo Clinic authors write in the May issue of Mayo Clinic Proceedings.... response." For more information for patients, the authors of the paper recommend that physicians refer patients to the International Hyperhidrosis Society ( w...Statin therapy cost-effective for a wider range of individuals
...2% 5-year risk, it was estimated to be 31,100. The authors believe that initiation of statin therapy should now be considered for people at lower risk for coronary or other major vascular events than is currently recommended. Professor Rory Collins (Clinical Trial Service Unit, University of Oxford, UK), pri...Type 2 diabetes is increasing among children all over the world
...for up to 45% of new cases among adolescents. The authors cite higher percentages in areas such as New York,...adults, in addition to high rates of obesity. The authors observe that there is a close tie between the rate of type 2 diabetes among adults in a specific pop...Active vaccine prevents mice from developing prion disease
...k is something that is very achievable." The authors of the new study are: Fernando Goi, Elin Knudsen, Henrieta Scholtzova, Joanna Pankiewicz, Einar M. Sigurdsson, and Thomas Wisniewski of the NYU School of Medicine; Fernanda Schreiber and Jose Alejandro Chabalgoity of the University of Uruguay; Richar......hool entry. In the second paper (Gupta et al), the authors suggest that cases in younger children may occur due to the recent fall in uptake of the MMR vaccine among 2 year olds - from around 92% in early 1995 to around 80% in 2003-4, and as low as 60% in some parts of London. Both papers conclude that the c...