Tag: "biomarker" at medical news
Brain region recovery possible in former methamphetamine users
...ssociated with drug abstinence," was measured as a biomarker
of recovery. Levels of NAA were abnormally low in all the methamphetamine users, the authors found. Levels were lower relative to the length of methamphetamine use, but did not change relative to the amount of time that the methamphetamine users had...
Variant in gene associated with telomeres predicts longer survival of deadly brain tumor
...s a way that these results can be used either as a biomarker
or to individualize treatment." For example, if the SS variant genotype of hTERT is confirmed to have better response to chemotherapy and radiation treatment, then it is possible that these therapies will extend survival for patients with glioblastom...
A candidate biomarker to improve treatment of lupus patients
...cent study provides the basis for a new laboratory biomarker
to better evaluate new therapies as well as to hel...l studies to validate the measurement of IFIG as a biomarker
for active lupus." Beyond its clinical applications, this study provides new clues to the underlying...
Mayo Clinic: Biomarker that may improve quality of life during treatment for colorectal cancer
... -- A Mayo Clinic-led study has revealed a genetic biomarker
that can predict which patients are most likely to experience unwanted side effects from one of the most commonly used and highly effective chemotherapy regimens designed to treat colorectal cancer. Conducted by the North Central Cancer Treatment Gro...
Potent spice works to block growth of melanoma in lab test
...er growth. "Curcumin affects virtually every tumor biomarker
that we have tried," says Aggarwal. "It works through a variety of mechanisms related to cancer development. We, and others, previously found that curcumin down regulates EGFR activity that mediates tumor cell proliferation, and VEGF that is involved...
Alcohol abuse: Early diagnosis is key to treatment success
...ers' licenses. "When there finally is an accurate biomarker
for alcohol abuse, it will be interesting to see w... an alcohol program regularly or submit to regular biomarker
testing.'" Harris added that biomarker
developments discussed at the symposium are critically impor...
New method rapidly detects potential bioterror agent
...ify strains, researchers examine the appearance of biomarker
proteins in samples. "In some cases, we classify a...ence of a biomarker. And sometimes we see the same biomarker
proteins, but at varying levels, in different strains," Fernandez noted. The researchers' detection ...
Biomarkers used to predict recurrent disease in hepatitis C transplant patients
...o underwent liver transplants examined a potential biomarker
that could be used to predict who might develop he... The authors note that alpha-SMA "is an attractive biomarker
because it is determined from the organ of interest and there is biological plausibility for why inc...
Test predicts risk of liver scarring after transplant, study shows
... The research team hypothesized that a known valid biomarker
of HSC activation alpha smooth muscle actin (alph... because they suggest for the first time that this biomarker
could help us identify liver transplant recipients with hepatitis C who are at high risk for progres...
Elevated blood levels of a protein are linked to asbestos-induced cancers
.... Pass. So, he says, "a rise in the level of this biomarker
in workers with past asbestos exposure may indicat...age disease." About pleural mesothelioma and the biomarker
The outlook for pleural mesothelioma patients who are diagnosed late is often grim: they may live ...
Enzyme complex thought to promote cancer development can also help prevent it
.... 14 issue of Science, researchers report that the biomarker
in question - an enzyme known as EZH2 - leads a du...h kinds of EZH2 that has been measured in previous biomarker
studies) since it is the one with oncogenic properties and appears to help cancer cells invade nearb...
Have researchers found a biomarker to signal a more agressive form of prostate cancer?
DENVER--Researchers say they have identified a biomarker
that indicates a more agressive form of prostate cancer. Fox Chase Cancer Center's chairman of radiation oncology, Alan Pollack, M.D., Ph.D., presented the findings today at the 47th Annual Meeting of the American Society for Therapeutic Radiology a...
Alternative tobacco products: A better, safer option for smokers?
... medicinal nicotine products as well as carcinogen biomarker
levels present in the users. The study compared the carcinogen levels of several types of oral tobacco products made in the U.S, which have carcinogen levels at least 100 times that of other consumer products designed for oral use. The lowest levels...
Biomarkers may provide important information for patients at risk for recurrent ischemic stroke
CHICAGO Measurement of two biomarker
levels in stroke survivors may provide predictive information for recurrent ischemic stroke beyond traditional risk factors, according to a study posted online today by the Archives of Neurology, one of the JAMA/Archives journals. The study will be p...
Alcohol biomarker test cuts care costs for chronically ill patients
Adding a new alcohol biomarker
test to patients' revelations about their drinking...avoiding some medical and legal costs. The alcohol biomarker
is approved by the U.S. Food and Drug Administration, but Fleming said that many primary care physic...
Study uncovers potential biomarker for lupus atherosclerosis
...SLE determined to have actual atherosclerosis. The biomarker
was similarly high in half of the 12 subjects with SLE that had suffered a stroke (cerebrovascular event). "We can clearly see from these results that HDL function fails to protect against cardiovascular disease in many SLE and rheumatoid arthritis p...
New studies identify advances in treatment of chronic myeloid leukemia
...ta and optimal inhibition of BCR-ABL activity from biomarker
analysis. Dose escalation to 90 mg BID was permitted in patients lacking response, and dose reductions to 50 and 40 mg BID were allowed in the event of intolerance. Complete blood counts were obtained weekly for the first 12 weeks, while bone marro...
Blood test can accurately diagnose heart failure in patients with kidney dysfunction
...ulness of testing for both NT-proBNP and a related biomarker
called BNP, and the conventional understanding was that NT-proBNP was the more affected of the two," says James Januzzi Jr., MD, of the MGH Cardiology Division, the paper's senior author. "However, while kidney disease did lead to higher values of N...
New study demonstrates combined techniques to detect, monitor Alzheimer's disease
...We presently don't have fully validated imaging or biomarker
measures that can help us monitor the development or progression of Alzheimer's in living people," explains Neil Buckholtz, Ph.D., chief of the Dementias of Aging Branch at the NIA. "This study represents one step in the progress being made toward id...
Biomarker for age-related macular degeneration found
...eine in their blood, an amino acid that is a known biomarker
for cardiovascular disease, may also be at an incr... elevated homocysteine in the blood may be another biomarker
for increased risk of AMD," said lead author Johanna M. Seddon, MD, director of epidemiology at the ...
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