Immune system lab model overcomes ethical limits on human hematopoietic stem cells studies
...s the process in which stem cells infused into the body are accepted, after which they produce the various types of blood cells normally found in the body. The model, called NOD-scid IL2Rnull, can be readily engrafted with human HSCs, which then develop into T cells, B cells, myeloid cells, natural kille...New fat is needed to clear old fat from the system
...005 -- Where fat comes from determines whether the body can metabolize it effectively. Researchers at Wash...ice were no different than normal mice in terms of body weight, body fat, metabolic rate and food intake. The effect of added dietary fat was duplicated whe...Two studies offer clues about how alcoholic behavior is 'switched' on
... the antagonist (10 and 30 milligrams per kilogram body weight) reduced drinking behavior in the alcohol-preferring rats; the highest dose decreased drinking (though less dramatically) in the non-preferring group, which drank less to begin with. The lowest dose (3mg/kg) had no effect in either group. None...Gender and sexual orientation influence preference for human body odors
...phia, one person's preference for another person's body odor depends in part upon the gender and sexual or...t is reflected in both the production of different body odors and in the perception of and response to body odors," remarks Monell neuroscientist Charles Wy...BMI just part of ischemic heart disease risk picture
...disease and may be present in people with a normal body mass index (BMI). St-Pierre and colleagues examined the data for a cohort of men to determine the effect of cumulative features of insulin resistance syndrome on the risk of ischemic heart disease associated with different BMI categories. They found ...Carbonated soft drinks and sleeping pills cause heartburn during sleep
...urn during sleep that were found include increased body mass index (BMI), various sleep abnormalities, hypertension, and asthma. "Heartburn during sleep is indicative of nighttime reflux, which has been shown to be associated with a more severe form of gastroesophageal reflux disease," said Dr. Fass. ...Study suggests antibiotic may limit or prevent vision problems caused by diabetes
...have shown that the changes diabetes causes in the body lead to increased production of cytokines, proteins that cause inflammation of the nerves. This study goes a step further to show that in early diabetes elevated levels of cytokines activate microglia, which produce neurotoxins and kill nerve cells. ...University of Manchester launches new anti-MRSA product
...eliminated and germs will not survive." The BioKab body and surfaces are impregnated at the manufacturing stage with IRGAGUARD - an inorganic antimicrobial. It works by breaking down and destroying cells of bacteria which come into contact with the cabinet. Silver ion, which is the active ingredient in IR...Hyperhidrosis and its treatment becoming better understood
...art of the brain controls the sweating response to body temperature, while another area controls the sympathetic, or emotional sweating response. For reasons unclear to hyperhidrosis researchers, the emotional component is in overdrive. The result is typically a healthy individual who perspires excessivel...Saving virtual lives with nanobots goal of UH-led project
...trol a team of nanobots within the simulated human body of a terminally ill patient. The nanobots are injected into the blood stream to locate and collect infected tissue. While attempting to deliver medicine to these sites, the nanobots are attacked by white blood cells in the patient's immune system. ...Spinoff company receives $2.5 million NIH grant to build prototype scanner
...reak away from the tumor can circulate through the body to seed cancer elsewhere (metastasis). Conventional mammography, little different than technology developed in the 1950s, spots a tumor at 11 millimeters in diameter on average. The problem is that the technology attempts to capture the image of a th...OHSU study says national injury prevention program working
..., he would be paralyzed from the chest down as his body and bike lay twisted and broken at the edge of the highway. After a month in a coma and years of rehabilitation, Burns' life shifted gears again, when he became a volunteer for ThinkFirst, a national brain and spinal cord injury prevention program wi...Type 2 diabetes is increasing among children all over the world
...ndition called insulin resistance. Initially, the body compensates for the resistance by increasing production. However, over time the ability of the pancreas to increase production doesn't keep up and blood sugar begins to rise, leading eventually to type 2 diabetes. Orit Pinhas-Hamiel, M.D. of Sheba Me...Penn study shows liver receptor key to diet-dependent differences in blood lipid levels
... expression of LXR in the liver is beneficial in a body full of natural molecules that bind to the LXR receptor, which are generated by the Western diet, but not when on a low-fat, healthy diet. However, this benefit is lost when a potent drug is added to the system. "The reason is that a different set of...Active vaccine prevents mice from developing prion disease
...rion disease is contracted when an animal eats the body parts of other animals contaminated with prions. W...related diseases, and prions can easily infect the body because they do not elicit any immune response. To create a vaccine that could rally the immune...Your heart could indicate whether you have kidney problems
...from ESRD. Together with blood pressure, age, and body mass index, different cardiovascular risk factors can have varied impact on kidney function. "Studies show that the mechanisms underlying renal function abnormalities in the general population are limited," states Paul E. De Jong, corresponding autho...Can rice bran oil melt away cholesterol?
.... Extrapolated to humans, a person with an average body weight of 154 pounds would get around 560 IU, which is close to the 400 IU of Vitamin E normally taken. (The upper tolerable intake of Vitamin E is 1500 IU). Researchers have been investigating natural ways (besides diet and exercise) to achieve l...Breast tumor's biological traits guide hormone therapy
...ors that inhibit the production of estrogen in the body have been found highly effective and in some cases superior. But whether women should take tamoxifen alone, an aromatase inhibitor alone, or tamoxifen for two years followed by an aromatase inhibitor are issues yet to be clarified by clinical trials....Moderate alcohol use linked to increase in breast cancer risk
... results were consistent regardless of the women's body mass index, type of alcoholic beverage consumed, or use of hormone replacement therapy.......e," says Rubenstein. "This study adds to a growing body of cost-effectiveness analyses that demonstrate a common principle: effective prevention with medicines is cost-effective compared to surveillance followed by just-in-time interventions, such as surgery." Statins were originally developed to lower ch...