Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
... JAMA/Archives journals. Oxidative damageharm to cells caused by exposure to oxygenmay contribute to the development of cardiovascular disease, according to background information in the article. In addition, compounds known as free radicals may damage artery linings, encourage blood clots and alter the ...DNA vaccine against multiple sclerosis appears safe, potentially beneficial
...stem attacks the myelin sheaths that protect nerve cells in the brain and spinal cord, according to background information in the article. The nerve cells axon, which transmits messages to other neurons, is eventually destroyed. The cause of MS is unknown...Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
...ons compensate by signaling the surviving dopamine cells to dramatically increase their activity and the output of dopamine. Eventually, the norepineprhine neurons die, the surviving dopamine neurons lose their ability to release extra dopamine, and symptoms start to appear." To test their hypothesis, th...Regulator of lipid metabolism ensures high quality breast milk
...D., observed that mice lacking PPAR in endothelial cells had trouble rearing their newborns. Although the mothers seemed perfectly normal, the nursing offspring soon stopped growing and lost their hair, says Wan. It took us some time to figure out what was going on. If the pups were given anti-inflammato...MRI finds breast cancer before it becomes dangerous
...56 %) with mammography. Breast cancer forms in the cells which line the inside walls of the milk ducts. The tumour initially remains in the milk duct and is therefor called " intraductal cancer" or DCIS (ductal carcinoma in situ). Although even at this stage it is called a carcinoma, it behaves actually li...Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
...cid reflux called Barretts esophagus, have altered cells in their esophagus containing shortened telomeres,...ate that the shortened sequences might allow other cells more prone to cancer to take over. The research supports why it is important to prevent reflux, be...New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
...ticipates in a stress-signaling pathway to protect cells from damage. In a paper published online in the J...e gene in estrogen receptor-positive breast cancer cells led to reduced sensitivity to Tamoxifen and Faslodex. According to Lombardi medical oncologist Mi...Penn study finds pro-death proteins required to regulate healthy immune function
...growth. The Penn scientists discovered that in the cells that lack the pro-death proteins Bax and Bak, calc...hor Craig B. Thompson, MD. It is well known that cells that lack Bax (Bcl-2-associated X protein) and Bak (Bcl-2-antagonist/killer) continue living under c...Chromatin remodeling complex connected to DNA damage control
...A damage is like a fire that spreads when impaired cells divide and multiply, then the DNA checkpoint and r...on of Ies4 to mimic constant phosphorylation, more cells were stuck in a checkpoint pause, blocking cell division. When phosphorylation was blocked, the cell...Pathway links inflammation, angiogenesis and breast cancer
...do its job suppressing cancer by forcing defective cells to kill themselves, programmed cell death known as apoptosis. "If you can control IKKa, you get a double-dip effect," Hung says. "You not only activate p53, the good guy, you keep the bad guy out of the contest." IKKa and IKK together help NF"B e...Stanford researchers find culprit in aging muscles that heal poorly
...uct, and that's exactly what happens with the stem cells in our aging muscles, according to researchers fro... as we age, the lines of communication to the stem cells of our muscles deteriorate and, without the full instructions, it takes longer for injured muscles t...NIH scientists target future pandemic strains of H5N1 avian influenza
...A) protein that directs the virus to bird or human cells and eliciting antibodies to it. What Dr. Nabel and his colleagues have discovered will help to prepare for a future threat, says NIH Director Elias A. Zerhouni, M.D. While nobody knows if and when H5N1 will jump from birds to humans, they have co...Hormone regulates fondness for food
...ht be the key. The hormone leptin is made by fat cells and circulates in the bloodstream to reach the brain where it acts to reduce hunger and increase fullness. The authors studied patients with a rare genetic disorder resulting in a complete lack of leptin. These patients eat excessively, like all type...Indiana University Imaging Center receives $6M grant for kidney research
...e detailed quantitative threedimensional images of cells and to analyze activities in living cellswithin the body. The school received its initial O'Brien Center grant of $5 million in2002. Along with research in kidney disease and development of imagingtechnologies, the center has served as an education...Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
...the decreased availability of thiamine in vascular cells in diabetes was linked to a marker of microvascula...ations. It likely reflects problems in endothelial cells (endothelial cells line the bodys entire circulatory system) and increased risk of atherosclerosis (...Stem cell transplantation procedure results in long-term survival for amyloidosis patients
...come results. AL amyloidosis occurs when plasma cells in bone marrow produce proteins that misfold and deposit in tissues, leading to organ failure and death. Between 1,200 and 3,200 new cases are reported each year in the United States, although researchers believe the disease is highly underdiagnosed....Rutgers professor Bart Krekelberg is named 1 of 20 US Pew Scholars for 2007
...h research has focused on the function of specific cells in individual areas of the brain, but not on the c... how they influence each other, and how individual cells affect the whole. The research will involve both studying the function of individual cells in his el...Electrical implant steadies balance disorder in animals
...known to wipe out the tiny hairlike projections on cells in the inner ear canals that are normally key to sensory balance function. Treated animals displayed unsteady walking and wobbly eye movements commonly seen in people with impaired balance. Precise measurements of eye movements, using a technique o...Green tea holds promise as new treatment for inflammatory skin diseases
...reated with green tea showed slower growth of skin cells and the presence of a gene that regulates the cells life cycles. Psoriasis, an autoimmune disease, causes the skin to become thicker because the growt......electric fields can disrupt the division of cancer cells and slow the growth of brain tumors, suggest labor...elds that jiggle electrically charged particles in cells back and forth hundreds of thousands of times per second. The electric fields have an intensity of o...