Loss of stem cells correlates with premature aging in animal study
...reservoir of specific adult stem cells. These stem cells dont divide as frequently as other cell types sinc...lead to natural breaks in DNA. But when these stem cells are needed, their progeny can rapidly divide and are able to replenish the tissue with new cells. ...UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells
...ering the particles into a variety of human cancer cells to induce cell death. The results suggest that the...nanoparticles and delivered them into human cancer cells to induce cell death. The beauty of our findings is that these nanoparticles are biocompatible, c...UK scientists set their sights on cure for AMD
...nd the University of Sheffield. The therapy, using cells derived from human embryonic stem cells to replace the faulty retinal cells that cause AMD, will be developed by the London Project to Cure ...Dartmouth's alternative breast imaging techniques sort abnormal from normal tissue
...fect the way a current flows, and different cancer cells have different electrical characteristics. MIS: This exam involves the propagation of very low levels (1,000 times less than a cell phone) of microwave energy through breast tissue to measure electrical properties. This technique is particularly s...GSK announces launch of largest ever Phase III trial in lung cancer treatment
... own immune response to identify and attack cancer cells in a highly specific manner. This novel cancer immunotherapy is developed using tumor specific antigens, delivered as highly purified recombinant proteins, and GSKs own proprietary Adjuvant Systems, which are specifically designed to enhance ASCIs an...Study identifies new regulator of fat metabolism
...otected from diet-induced obesity, had smaller fat cells and had more brown adipose tissue,says Maratos-Flier. But little was actually known about FGF21s physiologic roles. Working with Jeffrey Fliers lab, we were able to show that FGF21 is essential for fatty acid oxidation. Furthermore, she explains, w...Explaining a link between strokes and Alzheimer's
... by these low-oxygen incidents to a group of brain cells called astrocytes. When the brain is functioning n...r's Society, added: "The team examined the role of cells that support neurones in the brain. This is exciting because rather than focussing on neurones they ...MU researchers find mechanisms that may unlock answers to Alzheimer's disease
...type that provides nutrients to neurons. Microglia cells are immune cells activated for defense related functions. Effects of A-beta on astrocytes and microglia may create ab...Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
(PHILADELPHIA) -- The number of tumor cells circulating in the bloodstream of patients with me...r Center at Jefferson looked at circulating tumor cells (CTCs) in 240 men with metastatic prostate cancer that failed hormone-depletion therapy. They compar...Research shows survival benefit for leukemia patients treated with arsenic trioxide
... is a cancer of the bone marrow in which cancerous cells eventually crowd out the healthy blood cells needed for the body to function normally. Karen Shelton, a 58 year-old nurse from Kannapolis, was...U-M study finds lymphoma drug effective over long term
...ancerous cells. The radiation zaps these malignant cells with minimal exposure to normal tissues. With the Bexxar therapeutic regimen, a patient receives an injected test dose of radioactive Bexxar, followed one to two weeks later with a custom-tailored therapeutic dose. After that, the therapy is consid...Low doses of ecstasy associated with decline in verbal memory
... drug can harm the brain. Ecstasy may damage nerve cells that respond to the hormone serotonin, which is involved in mood, thinking, learning and memory. Thelma Schilt, M.Sc., of the Academic Medical Center of the University of Amsterdam, the Netherlands, and colleagues recruited 188 volunteers (average ...Stanford researchers track human stem cells transplanted into rat brain
...ve illuminated the path taken by human neural stem cells that were transplanted into the brains of rats and mice, and found that the cells successfully navigate toward areas damaged by stroke. The research group placed miniscule particle...Blocking stress protein decreases Alzheimer's peptide in mice
... showed that increased communication between brain cells also contributed to increased amyloid beta. When they directly placed CRF in the mouse brain, amyloid beta levels rose immediately. Mice given a CRF blocker and then stressed did not display increased amyloid beta. "There are very few known environm...Bias in statin trials, failure to control malaria, and more
...ates intracrine survival in human breast carcinoma cells through internally expressed VEGFR 1/FLT1 ...ates intracrine survival in human breast carcinoma cells through internally expressed VEGFR 1/FLT1 A study by Shalom Avraham and colleagues from the Be...Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research
...coveries of the chemical switch that turns healthy cells into cancer cells. The annual Pasarow Medical Re...itch that can trigger the uncontrolled division of cells -- the hallmark of many cancers. Discovery of this important signaling mechanism, which proved to be...Revlimid data presented at ASCO stands to change the way physicians treat multiple myeloma
...marrow that affects production of red cells, white cells and stem cells. It is the second most prevalent of the blood cancers, affecting an estimated 750,000 people worldwide, and in industrialized countries it is being diagnosed in growing in numbers and in increasingly younger people. The Revlimid/dexam...Chemotherapy may enhance the effectiveness of brain tumor vaccines
...rves to boost immune function, these hungry immune cells become even more effective in targeting and fighti...in tumor, were given both a vaccine aimed at tumor cells along with the chemotherapy drug temozolomide. "Conventional wisdom has been that chemotherapy, by...Adding radioimmunotherapy to chemo may help patients with lymphoma
...al antibody specifically designed to kill lymphoma cells with the help of a radioactive atom. We found that adding a radioactive monoclonal antibody to standard chemotherapy helped lymphoma patients achieve a higher complete response rate. We hope that this will translate into long-lasting remissions, ...Exploring better ways to determine when to change the course of treatment
Counting circulating tumor cells before and after the start of treatment for patients with metastatic colorectal cancer could help doctors determine when or if a change in treatment should be made. The results of a large, multicenter, international study laying the groundwork for s...