Sex hormones hold key to higher rates of abdominal aortic aneurysms in males
...ies in male sex hormones. They found that removing circulating androgens, including testosterone and dihydrotestosterone, from male mice lowers their risk of aneurysm to that of females, while giving females these same male sex hormones increases their risk to that of males. Tracy Henriques, a graduate student i...Researchers identify marker of heart disease in low-birthweight babies
...-1 bound up in the high density lipoproteins (HDL) circulating in their blood. These infants were born on average 1.3 pounds less and three weeks earlier than those who had normal HDL levels of the suspect particles. Results are published in the April 20 issue of the Journal of the American Medical Associatio...Other highlights in the May 4 JNCI
... measured as dietary intake and as the main active circulating form, known as pyridoxal 5'-phosphate, or PLP, is associated with the risk of colorectal cancer and colorectal adenoma in women by performing a nested casecontrol study of 32,826 women in the Nurses' Health Study who provided blood specimens between ...Atorvastatin shows promise in small trial for the treatment of mild to moderate Alzheimer's disease
...0 mg of atorvastatin calcium significantly reduces circulating cholesterol levels and may have a positive effect ...oms of AD come from the blood because of increased circulating levels." "Finally, although the results clearly hold promise, this was a pilot proof-of-concept tria...Obesity is risk factor for aggressive prostate cancer
...e, fat makes estrogen-like compounds, which lowers circulating levels of prostate specific antigen, or PSA, a marker for prostate cancer. If PSA levels are lower due to hormone changes from obesity, the prostate cancer is less likely to be detected at an early stage. Hormone changes observed with obesity also c...Physical activity associated with improved survival for women with breast cancer
...ysical activity has been linked to lower levels of circulating ovarian hormones, which may explain the relationship between physical activity and breast cancer. Lower estrogen levels among physically active women with breast cancer could potentially improve survival, although few data exist to support this hypot...Social support linked to prognostic marker for ovarian cancer
...ther behavioral factors are related to levels of a circulating protein, which at high levels is associated with a... social attachments had 1.7 times more IL-6 in the circulating bloodstream and 2.5 times more in the ascites fluid surrounding the tumor than women with strong soc...Mouse studies of oseltamivir show promise against H5N1 influenza virus
...d on oseltamivir against the H5N1 influenza strain circulating in Vietnam, found that the drug, sold commercially...earchers found that the 2004 H5N1 virus, currently circulating in Vietnam, is much more virulent than its 1997 predecessor. A longer course of antiviral treatment ...LSUHSC innovation in patient safety training to improve surgical outcomes
...m comprising surgery residents, anesthesiologists, circulating nurses, nurse anesthesia students, and medical students, will be thrown into a scenario where their patient develops a potentially fatal cardiac arrhythmia during a gallbladder operation. Other crises may occur as well, depending upon how the surgica...Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
... of stem cells out of the bone marrow and into the circulating blood, boosting the supply of marrow stem cells available for transplantation. Stem cell transplantation entails collecting certain types of cells known as hematopoietic stem cells from patients who receive treatment with high-dose radiation and/or c...Resistance to anti-flu agents increasing worldwide
... of resistance to amantadine and rimantadine among circulating influenza virus strains. However, it has been 10 y...ind such a dramatic increase in drug resistance in circulating human influenza viruses in recent years. Our report has broad implications for agencies and governm...Flavanols key to potential chocolate benefits
...ting sessions. There were significant increases in circulating nitric oxide and flow-mediated dilation after ingestion of drinks containing 176 to 185 milligrams of flavanols, a dose potentially exerting maximal effects. These changes correlated with increases in flavanol metabolites. In addition, the improvemen...Moderate exercise yields cardiovascular benefits
... maximum amount of oxygen that can be delivered by circulating blood to tissues in a given period of time while exercising. While all the exercise groups saw improvements in peak VO2 and TTE after completing their exercise regimens, the researchers noticed some interesting trends. "We found that when we compared...Immune therapy could treat leukemias, autoimmune diseases, transplant rejection
...the CD19 mAb treatment prevented the appearance of circulating and tissue tumor cells for up to seven weeks in al... by B cells, they found a significant reduction in circulating antibody levels as well as B cell mediated "humoral immune responses" in the animals, including redu...Cool therapy reduces brain injury and death from oxygen loss in newborns
... placing babies on a blanket initially filled with circulating 41-degree water. Both groups received standard newborn intensive care including monitoring of vital signs. When the infants were examined to assess their outcome at 18 to 22 months of age, 44 percent of those in the group treated with hypothermia ......ier rat study, Barr and Barr observed increases in circulating blood levels of serum cytokines. They are now finishing a study in which they are examining blood collected from humans diagnosed with repetitive strain injuries for these cytokines. Positive findings could aid earlier diagnosis and therefore earlier...New findings help explain how brain pathways control body weight
...t from the body (including information provided by circulating hormones such as leptin and ghrelin and from fuels such as glucose and fatty acids). It then integrates this sensory information with cues it has received from the outside world (such as aromas and other enticements) along with information gathered f...... group. Professor Ron Eccles said: "When colds are circulating in the community many people are mildly infected but show no symptoms. If they become chilled this causes a pronounced constriction of the blood vessels in the nose and shuts off the warm blood that supplies the white cells that fight infection. Th...Hopkins study may change rules for treating heart failure
... Increases in cardiac output, the amount of blood circulating in the body at any one time, were also greater in the control group, at 62 percent, than in the heart-failure group, at 39 percent. Meanwhile, increases in blood volume to the heart, when filling, remained the same between the two groups. And, whil...Early results using therapeutic pancreatic cancer vaccine show promise
...he rest of the patient's body to destroy remaining circulating pancreatic cancer cells with the same antigen profile. Patients get one vaccine injection eight to ten weeks after surgery, then four booster shots after chemotherapy and radiation. Laheru and his team completed enrolling patients in the study this ...