Intensive-care patients with alcohol problems are more likely to require mechanical ventilation
...es such as diabetes, renal failure, heart failure, cirrhosis of the liver, and chronic obstructive lung disease. These comorbidities make it more difficult to recover from critical illness. Furthermore, said de Wit, certain critical illnesses such as acute respiratory distress syndrome carry a high mortality...'Supersize me' mice research offers grim warning for America's fast food consumers
...onalcoholic fatty liver disease, which can lead to cirrhosis and, ultimately, death. "But we were also keeping the mice sedentary, with a very limited amount of activity." The study, which lasted for 16 weeks, had some curious results, says Tetri. "We had a feeling we'd see evidence of fatty liver disease ...New Mayo Clinic MRI technology enables noninvasive liver diagnoses
... a liver with fibrosis is firmer, and a liver with cirrhosis is almost rock-hard," says Richard Ehman, M.D., le...gestive track to the liver, usually as a result of cirrhosis of the liver. This study involved 35 individuals with varying degrees of chronic liver disease and 1...The hepatitis C link: Diagnose, treat, transplant
...lated cirrhosis, which is the most common cause of cirrhosis leading to orthotopic liver transplantation. We hope to further extend this research to understand how we can maximize the use of extended criteria donor organs. This includes hepatitis C positive graft that may benefit HCV-infected individuals who...Risk of lymphoma increases with hepatitis C virus infection
...ct, among other means. HCV is also known to cause cirrhosis and liver cancer. "Although the risk of developing lymphomas is small, our research suggests that screening of HCV-infected individuals could identify conditions which may lead to cancer. It might then be possible to prevent progression to lympho...Double the death rate from cirrhosis for 'blue collar' men
...amined death rates among Australian men from liver cirrhosis between 1981 and 2002. Their results were publi...ecause of their heavy and binge drinking. Liver cirrhosis accounted for 3.3 percent of all deaths among men aged between 15 and 64 in Australia in 2002 (543) ...Racial disparities in treatment of patients with cirrhosis and complications of portal hypertension
...ulation-based sample of hospitalized patients with cirrhosis and complications of portal hypertension. Using ...ple, the researchers included 63,696 patients with cirrhosis who were admitted to a hospital between 1998 and 2003 for a complication of portal hypertension. The...Liver stiffness indicates portal hypertension
...1 consecutive patients with diagnosed or suspected cirrhosis from chronic HCV infection. Each patient underwent transient elastography to measure liver stiffness. Immediately afterward, they underwent HVPG measurement and liver biopsy. The researchers then analyzed the data and compared the diagnostic tools. ...Outcomes for patients with hepatitis B who need liver transplants
...tabilize liver disease in those with decompensated cirrhosis are not available" the authors conclude. In an accompanying editorial, Myron Schwartz and colleagues from the Mount Sinai Liver Cancer Program at the Mount Sinai School of Medicine in New York say the study vindicates UNOS policy while reporting a...Gene chip discovery may lead to individualized treatment for 5 hereditary liver diseases
...to severe liver disease. In children, jaundice and cirrhosis are responsible for more than half of the need for liver transplantation. Previous research on humans identified five genes responsible for inherited forms of jaundice, Until now, the broad array of causes of cholestasis including genetic, metab...Interaction between lymph and liver cells may affect immune response
...ions associated with loss of fenestrations such as cirrhosis and old age," the authors conclude. "We have shown [in previous studies] that old age is associated with dramatic reductions in the fenestrations of LSECs therefore the altered immune responses of older people might in part be mechanistically linked ...Long-term effects of non-alcoholic fatty liver disease
... and it is important to prevent its progression to cirrhosis because once liver failure occurs in these cases t...thors were able to show that even patients without cirrhosis developed ESLD [end-stage liver disease], thus refuting the claim that non-cirrhotic NASH is 'benign...Higher levels of cells originating in bone marrow may be useful in prognosis of liver cancer
...ared them with blood samples from 16 patients with cirrhosis and 14 patients who were healthy. Since EPCs are difficult to isolate and quantify, they measured EPC levels using a specific method that allowed them to culture blood cells and count the number of colonies (colony formation units or CFU) formed by e...Researchers estimate significant fatty liver disease in children
...ns are significant because the disease can lead to cirrhosis of the liver, end-stage liver disease requiring a liver transplant, and liver cancer. The team found that in 23% of those children with fatty liver, the liver injury was severe enough to produce steatohepatitis, an inflammation caused by fat buildup ...Anti-inflammatory drug prevents liver cancer in at-risk liver patients
...over three years of follow-up, patients with viral cirrhosis treated with colchicine were significantly less li...iver. However, human trials on patients with liver cirrhosis demonstrated no significant efficacy in liver disease progression. Its effect on HCC prevention and ...Liver diagnosis breakthrough with Mayo Clinic MRI development
...sis, a common condition that can lead to incurable cirrhosis if not treated in time. Traditionally, liver fibrosis is usually diagnosed using needle biopsies, which can involve complications and may be inaccurate due to sampling errors. The new technology promises to provide an accurate, painless, and lower ri...Bone mass continues to increase in liver transplant patients, despite early loss
...re diagnosed either with end-stage primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC), where the bile ducts become inflamed and obstructed, causing bile to build up in the liver and damage it. Patients were examined before transplant, at 4 and 12 months following transplant, and every year...Combined liver-kidney transplant beneficial for patients with dual organ disease
...otentially reversible kidney failure combined with cirrhosis or another liver disease--is often treated with liver transplant alone and not a combined procedure. As waiting times for organs increase, more patients with hepatorenal syndrome will likely develop a chronic, irreversible condition that may require...Liver-kidney transplant reduces organ rejection, boosts recovery
...-- potentially reversible kidney failure caused by cirrhosis or another liver disease -- is often treated by liver transplant alone, not a combined procedure. As waiting times for organs rise, however, hepatorenal-syndrome patients face an increased risk of developing a chronic, irreversible condition that may...African Americans have lower response rate to standard therapy for hepatitis C
...ion for liver transplants in the U.S. HCV-related cirrhosis (disruption of normal liver function caused by various chronic progressive conditions) accounts for almost 50 percent of newly diagnosed liver cancers and approximately 10,000 deaths per year....