Tag: "compound" at medical news
Sucampo submits new drug application for lubiprostone
... on March 31, 2005 to market lubiprostone, a novel compound
with a unique mechanism of action, for the treatment of chronic idiopathic constipation (CIC) and associated symptoms in adults. Administered orally, the agent has been shown to work locally in the GI tract by activating specific chloride channels ...
Onion compound may help fight osteoporosis
...niversity of Bern in Switzerland have identified a compound
in the popular vegetable that appears to decrease ...nts of white onions and found that the most likely compound
responsible for the decreased bone loss was a peptide called GPCS. The researchers then obtained a g...
Prostate cancer therapy - study suggests new molecular screening theory
...te for Cancer Research (LICR). "Although the 2-ME compound
is in early clinical trials, no-one has fully understood the molecular mechanisms of how it causes the death of cancer cells, but not normal cells," says Dr. Marne Landstrm, the senior author of the paper published in the prestigious Journal of Biolo...
Researchers find that chocolate compound stops cancer cell cycle in lab experiments
...s how pentameric procyanidin (pentamer), a natural compound
found in cocoa, deactivates a number of proteins t...tially have effects on cancer cells, and a natural compound
in chocolate may be one," said the lead author, Robert B. Dickson, Ph.D., professor of oncology. "W...
Findings about anti-cancer agent could make it more effective
...an cancer. His most recent findings reveal how the compound
called FdUMP works to damage DNA, the geneti...h. Eleven years ago, Gmeiner set out to develop a compound
that would be more effective and have fewer side effects than fluorouracil, one of the most common c...
Environmental factors, particularly air pollution, increases risk of myocardial infarction
...of a mystery. Exposure factors that are thought to compound
the risk include passive smoking, air pollution, noise pollution and the chemical composition of drinking water. Even if such environmental factors give only a small increase in risk, they can have serious consequences for public health bearing in mi...
Eliminating enzyme dramatically reduces cardiovascular disease
...reatment for protecting against heart disease is a compound
that decreases ACAT2 activity," said Rudel. He said that one day, it may be considered important to test how much of patients' cholesterol was altered by ACAT2, in addition to testing their levels of high-density lipoprotein ("good") and low-density...
UT Southwestern researchers show new drug may help treat certain forms of leukemia
...eevec resistance and looking at combining this new compound
with other drugs. "CML patients may soon have multiple choices with Gleevec and any one or all of the additional classes of drugs in development," Dr. Ilaria said. "These compounds also may work on other solid tumors, so it will be very interesting t...
Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
...ny-stimulating factor (G-CSF) to create a new oral compound
that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloodstream to be used by the body, according to research from the University of Southern California School of Pharmacy. This techn...
Innovative study finds way to 'bio-synthesize' an anti-cancer compound
... squirts could be used to biosynthesize a chemical compound
that may help fight cancer. The photosynthetic mic...ed up the time it takes for a drug to go from lead compound
to actual drugs." By proving that the patellamide compounds are made by the microbes inside sea squ...
Older adults with insomnia report falling asleep faster with ramelteon
...me administration of ramelteon, an investigational compound
currently under review for the treatment of insomnia, significantly reduced time to fall asleep in older adults with chronic insomnia. Additionally, no rebound insomnia or withdrawal effects were observed. An estimated 60 million people in the U.S. ...
Radioactive isotope is effective against neuroblastoma
Attaching a radioactive chemical to a compound
that binds to tumor cells, physicians can selectiv...a cancer of the peripheral nervous system. Using a compound
called MIBG in 167 patients with neuroblastoma, researchers achieved a high number of responses with...
While on trail of dioxin, scientists pinpoint cancer target of green tea
... protective effects, and that could help us find a compound
that is much more potent." Palermo, Gasiewicz, and current undergraduate Claire Westlake discovered that a chaperone protein known as HSP90 is involved in conferring green tea's protective effects. Other researchers have shown that many cancer cells...
Antibody combined with cancer drug shows promise against breast tumors
...ns Comprehensive Cancer Center, found the antibody compound
3G4 was effective as a vascular targeting agent (V...n of 3G4 and docetaxel was much better than either compound
used by itself, Dr. Thorpe said. In mice with breast cancer tumors, growth was suppressed by 50 perc...
Study shows grapefruit extract can heal stomach ulcers
...ing by using a combination of acetic acid (an acid compound
used to induce experimental ulcers) with or without a COX-1 inhibitor (indomethacin, 2 mg/kg) and a COX-2 inhibitor (rofecoxib, 10 mg/kg). Rats treated with GSE at 10 mg/kg experienced a 50 percent reduction in gastric acid secretion, and a progres...
As morphine turns 200, drug that blocks its side effects reveals new secrets
...in 1806, he managed to isolate an organic alkaloid compound
from the resinous gum secreted by Papaver somniferum -- the opium poppy. Serturner found that opium with the alkaloid removed had no effect on animals, but the alkaloid itself had ten times the power of processed opium. He named that substance morph...
Ramelteon demonstrates no abuse potential according to study results
...study indicated that ramelteon, an investigational compound
currently under review by the FDA for insomnia treatment, had no more potential for abuse than placebo in individuals with a history of polydrug abuse. These results, presented at the 2005 American Psychiatric Association Annual Meeting, showed tha...
In those genetically predisposed, 'developmental reprogramming' could explain cancer risk
... are susceptible to benign uterine tumors, and the compound
used was diethylstilbestrol (DES), a banned estrogenic anti-miscarriage drug, the researchers say their conclusions likely have relevance for humans who inherit defective tumor suppressor genes that make them susceptible to a number of different canc...
Derivatives of cannabis for anti-cancer treatment win Kaye Award for Hebrew University student
...merous mechanisms. Additionally, the most active compound
in the series developed by Kogan, as well as some other cannabinoids, were found by Kogan and Prof. Ruth Galilli of the Hebrew University to have anti-angiogenic properties. Angiogenesis, the process of new blood vessel formation, is crucial for tumo...
Endocrine Society honors UNC physician for key contributions to hormone research
...ting understanding of the action of the biological compound
scientists call IGF-1. He established the usefulness of IGF-1 as a marker of growth hormone action and revolutionized the diagnosis of acromegaly. Acromegaly is an uncommon but debilitating hormonal disorder during which the body excessive secretes g...
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