Reanalysis of controversial meta-analysis says writing off rosiglitazone may be premature
... benefit or risk of rosiglitazone will resolve the controversy about its safety." In an Annals of Internal Medi...esigns and protocols. Therefore, they believe, the controversy over rosiglitazone's risk will only be resolved when clinical trials focusing on all these issues ar...Annals of Internal Medicine tip sheet for Aug. 7, 2007, issue
...nd weighting methods. Authors say that the risk controversy will only be solved with prospective clinical trials designed for the specific purpose of establishing the cardiovascular benefit or risk of rosiglitazone. (This Perspective piece is published early online by Annals of Internal Medicine at www.anna...International studies show high efficacy for HPV vaccine
...ar for use in females 9 to 26 years of age. While controversy has been raised about giving pre-adolescent girls a vaccine for a sexually transmitted disease, Dr. Ault argues, "young women, young girls make very good immune responses to this vaccine, so that will enhance their protection. Widespread immunization...Folic acid supplementation lowers stroke risk
...an accompanying comment caution that there remains controversy as to whether folic acid supplementation can lead to improved outcomes for other cardiovascular conditions. Professor Xiaobin Wang, Children's Memorial Hospital and Children's Memorial Research Center, Northwestern University Feinberg School of Med...New guideline for treating Lyme disease
...l Lyme disease, there continues to be considerable controversy and uncertainty about the best approach to treating neuroborreliosis, in which Lyme disease involves the nervous system," said lead guideline author John J. Halperin, MD, with Atlantic Health in Summit, NJ, and Fellow of the American Academy of Neuro...Testing the taser on human subjects -- preliminary physiological measurements
There has been some controversy regarding the use of the Taser in controlling subjects in police custody, including reports of deaths. In a paper to be presented at the 2007 Society for Academic Emergency Medicine (SAEM) Annual Meeting, preliminary results of Taser exposure on heal...Infants with bronchiolitis may benefit more from albuterol
...tion, epinephrine and albuterol, and there is some controversy and passion involved in the choice of medication. In a paper to be presented at the 2007 Society for Academic Emergency Medicine (SAEM) Annual Meeting, a double-blind randomized clinical trial involving over 700 infants over a three year period show...Study shows continued success for new HPV vaccine against virus responsible for cervical cancer
...ar for use in females 9 to 26 years of age. While controversy has been raised about giving pre-adolescent girls a vaccine for a sexually transmitted disease, Dr. Ault argues, "young women, young girls make very good immune responses to this vaccine, so that will enhance their protection." Researchers believe ...HCV patients survival after liver transplantation is not improving
...ation with worse outcomes in recent years, and the controversy that seems to surround this observation, is likely due to differences in distribution of these variables from study to study, from center to center, and from year to year." For future studies, she suggests that researchers use large databases to id...New guideline for screening mammography for women 40 to 49 years of age
... Choe, MD, MPRH, wrote: "In the face of continuing controversy about the evidence, our priority now should be to help women make informed decisions." ACPs clinical guidelines are developed in an explicit, rigorous process based on extensive review of available scientific evidence. They are considered "evidence...Drug safety recommendations lack scientific evidence
...ck up the IOMs recommendations. The current drug controversy is largely due to the withdrawal of Vioxx from the market, but the decrease in drug approval times thanks to the Prescription Drug User Fee Acts (PDUFA), and undue influence from the pharmaceutical industry that these acts may have invited have also ...Existing research supports metabolic syndrome link to cardiovascular disease
...t was fascinating to us was the fact that all this controversy in the field existed despite the prior publication...obese individual may have an increased risk. "The controversy has not ended," Dr. Diamant continued. "Questions still exist: Does the metabolic syndrome fulfill t...Study finds differences between blood pressure medicines and newly-diagnosed diabetes
...int out that their data do not address the ongoing controversy about whether new-onset diabetes leads to as many heart attacks, strokes or death, as long-standing diabetes, which will require more studies. The authors' data do suggest, however, that the differences between antihypertensive drugs regarding the ...UGA professor finds that confusion about Calories is nothing new
...y food contains. Hargrove found that there's some controversy about who "invented" the Calorie. Some references show that two Frenchmen, P.A. Favre and J.T. Silbermann, invented the Calorie in 1852. Other texts state that a German physician, Julius Mayer, effectively invented the Calorie in a study he published...No benefit to mechanically opening arteries days after a heart attack
...ractice. "OAT was created to help resolve a controversy that affects more than 100,000 heart attack survivors each year in the U.S. alone," said Judith S. Hochman, M.D., Director of the Cardiovascular Clinical Research Center at NYU School of Medicine and the lead author of the new study. She estimated th...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
...rotective genes. "There has been uncertainty and controversy about whether apo A-I Milano is a better form of HDL than the "wild type" (regular) apo A-I in terms of protective effect against atherosclerosis and vascular inflammation, which are tied together," said Prediman K. Shah, M.D., director of the Divisi...Is Clostridium difficile-associated disease linked to use of common stomach medication?
...ents. CDAD also occurs in the community. Recently, controversy has surrounded a possible link of community-acquired CDAD to the use of proton pump inhibitors (PPIs), drugs commonly used to suppress acid production in the stomach. Dial and colleagues, in a study using data from the United Kingdom's General Pract...2006 Science-in-Society award winners announced
...ro fertilization (IVF) draws parallels between the controversy over IVF in the 1970s and the current controversies over human cloning and stem-cell research. The judges cited Henig's, "Very absorbing and well-written account of progress in a scientific field that has direct impacts on human life." Newspaper--J...First study to show how immune cells 'speak' to each other in vivo
...ng to the researchers, this work should settle the controversy over the existence and functional significance of mature immunological synapses in vivo during antiviral immune responses. The findings will allow further experimental exploration of immunological synaptic function during normal and pathological imm......or identification, the Monell researchers solved a controversy centering on whether the brain processes olfactory information in a similar manner to how it processes visual and auditory stimuli. "Previous published work suggested that olfaction was different from vision and audition in lacking this fundamenta...