West Africa: meningitis epidemics driven by the wind
...st time quantified this link between the epidemics cycle and climate variations. Statistical methods brought out evidence of a coincidence between the seasonal variability of the number of cases of meningitis recorded in Mali and the climate dynamics on the scale of this zone. The Harmattan winds are the ...Study finds that women with PCOS are at increased risk for cardiovascular disease
...nditions would exhibit more hormonal and menstrual cycle irregularity than women with PCOS only. It is estimated that five to 10 percent of reproductive aged women suffer from PCOS. While there is no actual cure for PCOS, researchers are working to identify effective treatments as well as possible cause...Vigorously active adolescents are leaner, fitter
...rous physical activity. However, studies show that cycle can be moved in a positive direction with controlled physical training. "Based on this study, what you have on average is below an hour and for girls, way below," Dr. Gutin says. Most of the adolescents in this study * and likely generally * need to...Measuring enzymes at end of cancer pathway predicts outcome of Tarceva, Taxol
...les that allow a cell to grow and divide. CDK cell cycle enzymes are the end target of numerous cellular pa...eve that it functions in part as a monitor of cell cycle activity. Ueno theorizes that if something goes wrong during division - such as if Taxol is interrup...SKCC's Gennadi Glinsky addresses predicting risk in cancer treatment outcome
...ous) cells, it may contribute to the survival life cycle of cancer stem cells and promotes tumor progression and metastasis. Thus, when this signature expression is found in tumors, there is a high probability of unfavorable therapy outcome, the researchers concluded. However, if this signature expression...VELCADE for injection receives EU marketing authorisation for second-line use in multiple myeloma
... the backbone at an earlier stage in the treatment cycle have been highly promising." VELCADE offers a completely novel approach to treating multiple myeloma by acting on a unique target in cells called the proteasome. First approved in Europe on 26th April 2004 for the treatment of multiple myeloma pat...Exercise training in ordinary people affects the activity of 500 genes
...genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differ...ow that hundreds of genes are activated by regular cycle training for six weeks in young healthy men. Some of these genes are most likely linked to diabetes ...Fear of falling: It's not only grandpa's phobia
...ling that they become less active, which creates a cycle that causes frailty and illness, according to findings in the May issue of the Journal of Gerontology: Medical Sciences. "Among middle-aged African-Americans, there's this huge fear of falling which many of us thought existed only in older adults," ...Changes in brain receptors linked to seizures and anxiety during the menstrual cycle
...." Basing their findings on a study of the estrous cycle in mice--the equivalent of the human menstrual cycle--the researchers found that a specific subclass of the receptors called GABAA receptors change in the hippocampus during the cycle. These changes take place in a part of the brain where progesteron...Still have to swab those tonsils, Mayo Clinic study finds
... strep using two tests: standard culture and rapid cycle real-time polymerase chain reaction, technology that amplifies DNA. Strep was detected in one or more of the sampled sites in 41 cases; 29 of these were detected at the tonsil surface. Both testing methods were positive for strep in 28 of these 29 ca...Medical journals are an extension of the marketing arm of pharmaceutical companies
...d of year budget by firing an editor." How can the cycle of dependency between journals and drug companies be broken? "Firstly, we need more public funding of trials, particularly of large head to head trials of all the treatments available for treating a condition." "Secondly, journals should perhaps sto...Researchers prevent post-traumatic brain damage
...lammation after injury. At the same time, the cell cycle in neurons is activated, but because these nerve c...ts the concept that we now need to target the cell cycle in brain injury, whether it is with this drug or others," Faden said. Eventually, the researchers h...New stomach cancer therapy potentially more convenient and better tolerated
...and took a week off to recover before starting the cycle all over again. In all, 41 patients participated and were evaluable; researchers have examined information on the drug's safety in 30 patients and on the drug's effectiveness in 20 patients. In the 13 patients whose cancer responded to the drug, tum...JAMA study finds whooping cough vaccine effective, safe for teens and adults
...es for adolescents and adults, we can complete the cycle of immunization with booster shots to finally eliminate whooping cough in the United States." Study Details The JAMA study 5-component vaccine is composed of four protein fragments from the pertussis bacterium that help it cling to lung tissue, ...High school start times deprive teens of sleep, affect academic performance
...in the morning did not modify students' sleep-wake cycle or improve daytime performance during weekdays pro...te on weekends is part of their children's in-born cycle and not 'lazy' or antisocial behavior," the researchers said. Finally, this sleep study forged colla...Study shows ramelteon reduced insomnia symptoms in elderly
...4-hour biological rhythms including the sleep-wake cycle and is also called the body's "master clock." WHY: An estimated 60 million people in the U.S. suffer from insomnia, and approximately half of all older adults experience one or more symptoms of insomnia at least a few nights per week....Revealed: The true cost to the nation of multiple pregnancies
...roduction are limited to the cost of the treatment cycle alone. However, it seems clear to me that it is e...cy rate as transferring two or more embryos in one cycle and with far fewer risks to the mothers and babies. With older women, or those with more problems,...Nature publication reports key links between mechanisms of aging and metabolic disorders
...s the authors note, "Eventually, this feed-forward cycle leads to an altered metabolic state involving very high levels of insulin (hyperinsulinemia) induced by resistance to insulin, even under fasting conditions. This state triggers a constellation of related complications, collectively referred to as m...Nutritional info helps teens make better choices
...e next six weeks the second time through the menu cycle the cafeterias posted point-of-selection nutrition information for each entree. For pasta, sandwich and potato bars, cafeterias posted nutrient contents of typical choices for comparison. Labels included serving size; calories; total and saturated...Mood lighting: Penn researchers determine role of serotonin in modulating circadian rhythm
...body functions on roughly a 24-hour schedule, this cycle is capable of being reset by environmental disturbances. In Sehgal's lab, fruit flies provide the model system for examining entrainment, the synchronization of the internal clock to the environment. "In humans, a light pulse in the early evening del...