Tag: "cyclic" at medical news
Risk of womb cancer varies according to the type of HRT used
... than non-obese women), use of both continuous and cyclic
combined HRT significantly reduced the incidence of womb cancer, whereas tibolone and oestrogen-only HRT had little additional effect on incidence. In August 2003, The Lancet published data from the Million Women Study on breast cancer (Lancet 200...
Innovative study finds way to 'bio-synthesize' an anti-cancer compound
...Genome Sequencing). Because patellamides are small cyclic
peptides (consisting of eight amino acids), scient...t thought that as in the case of many other small cyclic
peptides the biosynthetic mechanism involved a "non-ribosomal peptide synthetase," a large multimod...
The Cochrane Library newsletter, 2005, issue 3
...e: Edelman et al: Continuous or extended cycle vs. cyclic
use of combined contraceptives for contraception. The Cochrane Database of Systematic Reviews 2005 Issue 3 Pain generated by damage to the nervous system can be treated with antidepressants Antidepressant drugs such as amitriptyline are effective...
Brain protein linked to alcoholism and anxiety
... researchers focused on a molecule called CREB, or cyclic
AMP responsive element binding protein, which is thought to be involved in a variety of brain functions. When CREB is activated, it regulates the production of another brain protein called neuropeptide Y. The higher-imbibing P rats were found to have...
Viagra blunts effects of stress on the human heart
...me is involved in the breakdown of a key molecule, cyclic
GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway blocked in the penis by sildenafil to prevent the relaxation of blood vessels and maintain erections....
What makes the brain tick, tick, tick. . .
...rom the visual system and outputs that control the cyclic
release of circadian hormones. "So, this process has to be distributed so it can integrate information from all the senses," said Meck. "But more importantly, because it's involved in learning and memory, you could argue that time isn't directly per...
A recipe for overeating: Studies outline dangers of mixing stress, deprivation and tempting foods
...fter rats experienced both foot shock (stress) and cyclic
caloric restriction (dieting). Either caloric restriction or stress alone were not enough to produce changes in food intake, but stressed and underfed rats ate twice the normal amount of Oreo cookies, which rats find rewarding. In other words, anim...
Adults also suffer from cyclical vomiting syndrome
... of our adult CVS patients, panic attackstriggered cyclic
vomiting episodes". Most patients had elements of bothmigraine tendency and anxiety complicated by panic attacks. While panic attacks are uncommon in pre-adolescent children, children sufferingfrom CVS are known to have higher rates of anxiety than c...
Polymorphism and antibodies associated with highly increased risk of rheumatoid arthritis
...TPN22 gene and test positivefor antibodies against cyclic
citrullinated peptide are much more at risk ofdeveloping rheumatoid arthritis than people who only have one of these markers.A study published today in the journal Arthritis Research & Therapy revealsthat a group of people who have a specific genetic...
JCI table of contents: May 4, 2006
...king a critical loop of TNFR and RANK with a small cyclic
peptide allows the inhibition of RANK ligandinduced bone breakdown and resorption in mouse models of osteoporosis. The authors used molecular modeling to demonstrate the exact region where the peptide binds and interferes with RANK signaling. These f...
Study shows rapid return to menses once oral contraception stopped
...thout a placebo interval. In contrast to a 28-day cyclic
regimen, this regimen would be taken every day of the year, without a placebo (or sugar pill) interval, resulting in a temporary interruption of menses. The follow-up study after a Phase 3, multicenter, open-label study of the safety and contraceptiv...
Inconsistent access to food in low-income households may contribute to weight gain
...urther research is needed to better establish that cyclic
purchasing leads to cyclic
consumption patterns, and that the cyclic
consumption patterns lead to gradual weight gain over time...
Studies to date say erectile dysfunction drugs affect other systems, mostly for the better
...the enzyme's action results in increased levels of cyclic
guanosine monophosphate (cGMP) and nitric oxide (NO), biochemicals that promote smooth muscle relaxation and increased blood flow in erectile tissue. According to the article, PDE-5 inhibitors can be effective in treating erectile dysfunction even f...
Preventive ovary removal linked to early death in younger women, Mayo Clinic discovers
...ally from one's own ovaries with daily and monthly cyclic
variations -- may not be the same as the effect of estrogen replacement therapy. The study's investigators propose several theories to explain the finding of increased early deaths for younger women who have preventive ovariectomy without adequate...
Rheumatoid arthritis and sex differences
...disease: rheumatoid factor (RF) and antibodies to cyclic
citrullinated peptides (CCP). Comparisons of demographic and clinical features between men and women with RA revealed several differences. Although male patients had significantly later onset of RA, they showed more signs of erosive disease, were m...
Targeted cancer drugs may work by disrupting balance of cellular signals
... at different rates, giving these medications in a cyclic
fashion, rather than continuously as currently prescribed, might better take advantage of the temporal windows of vulnerability and could possibly avoid drug resistance. Drugs that target the survival and cell death signals themselves may present an...
Sticky proteins provide new insight into drug action
...hould mean the alpha subunit enables production of cyclic
AMP, which increases the heart rate, while the bet...for some time that while epinephrine does increase cyclic
AMP in heart cells, it does not activate ion channels. While this situation makes sense because the...
Cyclic vomiting syndrome: Recurring and unexplained episodes destroy teeth
... and problems are more prevalent in children--like cyclic
vomiting syndrome (CVS). CVS mainly affects children, and is something of which parents should be aware. According to a recent report in the November/December 2006 issue of General Dentistry, the Academy of General Dentistry's (AGD) clinical, peer-r...