Tag: "defects" at medical news
Maternal obesity prior to pregnancy associated with birth defects
... in eight states whose babies were born with birth defects
between 1997 and 2002. The women were contacted be...ared with 4,065 women who had babies without birth defects
during the same time period. Mothers of babies with the following seven of 16 birth defects
W.M. Keck Foundation announces 2007 class of Distinguished Young Scholars in medical research
...l cells, the research has the potential to uncover defects
in chromosome regulation that cause malignancy, which may lead to advances in combating cancerous cells in the body. Wallace Marshall, Ph.D., Department of Biochemistry, University of California, San Francisco Dr Marshall investigates how cilia,...
Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
...ined half the normal amount of ZMPSTE24. Genetic defects
in ZMPSTE24 in humans lead to an accumulation of p...drome. Progeria syndromes can be caused by genetic defects
that interfere with the conversion of prelamin A to lamin A. Since HIV protease inhibitors inter...
Studies show antidepressants not linked to birth defects
...a small increase in the risk of certain rare birth defects
but they were different birth defects. Dr. Michael Katz, acting Medical Director of the March of Dimes, said the studies show how important post-market surveillance is in assessing the safety of medications in pregnancy. During pre-approval, dru...
UK scientists set their sights on cure for AMD
... suffer blindness through the condition, caused by defects
in the retinal support cells. There is currently n...h an interest worldwide. AMD is associated with defects
of the retinal support cells the retinal pigment epithelial cells (RPE). The rods and cones (the ph...
New hope for severe heart disease patients
...ndergone multiple surgeries to try and correct the defects
causing their heart to malfunction and were on the maximum doses of conventional medicines, yet still experienced chest pain from even the slightest exertion. "However," he cautioned, "this was a safety trial and therefore was not placebo controll...
UCLA pediatrician honored with prestigious achievement award
...e the identification of white blood cell phagocyte defects
in premature infants, the demonstration of profound T-cell defects
in children with the malnutrition conditions known as kwashiorkor and marasmus, and transmission of ...
How insulin-producing cells develop -- new finding could help fight against diabetes
...cells develop we may eventually be able to reverse defects
in the growth of these cells in patients with diabetes. Research like ours is opening up whole new sets of targets for drug treatments." The researchers reached their conclusions after conducting research on tissues cultured from the primordial pa...
UC Irvine researchers reveal first images of brain changes associated with memory
...gtons disease. They discovered that these synaptic defects
can be fully reversed through treatment with a bra...The researchers are now working to see if such LTP defects
are present in mouse models of common forms of human mental retardation....
Thymus transplants gives hope to babies with fatal immune disease
... also can have a range of problems including heart defects
and unusual facial features. However, about 1 percent of these babies have no thymus at all, a situation that ends in death, usually by infection. These are the patients who are candidates for thymus transplantation. "We want people to know that wh...
Coenzyme Q10 does not improve Parkinson's disease symptoms
...eurodegenerative disorders linked to mitochondrial defects
or oxidative [oxygen-related] stress, such as Huntington's disease and Parkinson's disease," the authors write. Previous studies indicate that high doses of CoQ10 (1,200 milligrams) may slow the deterioration associated with Parkinson's disease. Al...
Novel catheter technique successfully patches holes in the heart
... The patch successfully closed ventricular septal defects
(VSDs)or ruptures in the wall between the right and left ventriclesin nearly all patients, allowing blood to circulate normally again and relieving fluid back-up in the lungs. After recovery, patients were able to return to active lives. "Patients ...
JCI table of contents: May 10, 2007
...to lack the gene CalDAG-GEFI have a combination of defects
in their leukocytes and platelets, similar to thos... in integrin activation. They observed significant defects
in beta1- and beta2-integrinmediated adhesion of CalDAG-GEFIdeficient neutrophils, which impaired th...
Stanford researchers identify immune dysfunction in melanoma patients
...nt for only those patients whose immune cells have defects
in that pathway. That means patients who wouldn't benefit from the treatment could avoid suffering through interferon's flu-like side effects....
New, less painful wound treatment for pediatric patients
...h large and complex wounds, such as abdominal wall defects
or disrupted surgical wounds," says Dr. Olutoye. "Not only is the therapy very effective, but it eliminates the need for dozens of painful and frightening gauze dressing changes." According to Dr. Olutoye, the therapy offers other benefits. Because...
'Wrapping' Gleevec fights drug-resistant cancer
...s. "Like virtually all proteins, KIT has packing defects
that leave some hydrogen bonds poorly shielded from water attack," Fernandez said. "These bonds, which are called dehydrons, are in the twilight zone between order and disorder." In KIT, there is a dehydron near the active site that plays a key rol...
Anti-dandruff compound may help fight epilepsy
...he brains off switches fail in part due to protein defects
that prevent potassium from exiting nerve cells and calming them. Channels that carry potassium, says Min Li, Ph.D., professor of neuroscience at Johns Hopkins, must open on cue to make sure nerve cells only fire for defined periods of time. In the...
Jefferson immunology researchers show blood-brain barrier damage could affect MS severity
...be expected to develop EAE because they have major defects
in their immune system are still able to develop disease," though at different rates, he notes. However, mice missing the immune protein TNF-alpha often did not show disease, despite the increase in brain barrier permeability, causing the scientis...
Washington University surgeon develops treatment for foot deformity
...both healthy children and those with genetic birth defects
and neuromuscular disorders. Matthew B. Dobbs, M.D., who performs surgeries at St. Louis Children's Hospital, developed a treatment for CVT that involves gently manipulating the foot and applying long leg casts weekly for four to six weeks to gradu...
Children's Hospital Boston presents at the American College of Cardiology Scientific Sessions
...Monday, 3/26, 4 p.m. CT) Treating congenital heart defects
in babies still in the womb is a high-risk procedure, but one that can improve babies outcomes after birth. Researchers at Childrens Hospital Boston and Brigham and Womens Hospital reviewed the cases of 80 fetuses who had prenatal cardiac interventio...
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