Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis
...thogen and is strongly associated with respiratory deterioration and mortality. Over time, the bacteria transforms into treatment-resistant variants, and early detection is seen as key for aggressive antibiotic treatments to delay its growth. In the study, graduate student Michael Kambourse, working with Blake and...Camryn Manheim speaks out about rheumatoid arthritis
...icult. If not properly treated, RA also can cause deterioration of the joints, which can worsen over time and lead to permanent deformity or disability....Tracking desertification with satellites highlighted at UNCCD COP
...f productivity of vulnerable dryland areas by soil deterioration and erosion as well as the long-term loss of natural vegetation. Such drylands cover 40% of the world's land surface, and are the habitat and source of livelihood for more than one billion people. Of the 5200 million hectares of drylands used f...Denying joint replacements based on prejudice...and is false economy
...ows that delaying joint replacement surgery causes deterioration of functional capacity, which is difficult or impossible to reverse after later operation. "This is rationing by any other name," he says....Metabolic syndrome identified as risk factor for kidney-pancreas transplant patients
...e risk of heart disease, is also a risk factor for deterioration of kidney function in simultaneous kidney-pancreas...developing strategies to prevent or slow a gradual deterioration in kidney function that can lead to the need for a second transplant. Previous research had shown t...Diuretics reduce risk of death from congestive heart failure
Diuretics reduce the risk of death, delay heart deterioration and improve exercise capacity in patients with congestive heart failure, a new review of studies shows. Although widely used for quick relief of CHF symptoms -- cough, shortness of breath and swelling in the feet, legs and ankles -- up until now it w...Calcium plus vitamin-D supplementation does an older body good
...ces the gain, leading to low bone mass, structural deterioration of bone tissue, fragility and an increased susceptibility to fractures of the hip, spine and wrist. An estimated 44 million Americans either have or are at risk for osteoporosis, which contributes to about 300,000 broken hips in the United States eac...NIH seeks strategies to preserve brain health
...if physical activity can protect against cognitive deterioration "would be of great public health importance because physical activity is relatively inexpensive, has few negative consequences, and is accessible," the report says. A number of studies suggest a protective effect, and clinical trials are underway to ...New study says heart health and lifestyle are associated with maintaining brain health as we age
...hysical activity were to protect against cognitive deterioration in the elderly, it would be of great public health importance because physical activity is relatively inexpensive, has few negative consequences, and is accessible to most elders." And they said that increasing physical activity "could have a dramati......ring stroke and Alzheimer's disease. Indeed, brain deterioration after stroke is associated with elevated levels of glutamate -- the major excitatory neurotransmitter in the mammalian central nervous system (CNS) -- in the plasma and cerebral spinal fluid. One possible explanation for this glutamate build-up, rep...New study shows benefit of early therapy in HIV-infected infants
...l recovery. They found that the risk of subsequent deterioration was similar for children initiating treatment in all age groups. Still, because initiating effective antiretroviral therapy before 5 months of age was strongly associated with more rapid improvement in CD4 cell count, the authors conclude it should b...Drug effective for severe Alzheimer's disease
...n reverse some aspects of cognitive and functional deterioration seen in patients with severe Alzheimer's disease, ... "Donepezil slows, and can reverse some aspects of deterioration of cognition and function in individuals with severe Alzheimer's who live in nursing homes."...Reduced insulin in the brain triggers Alzheimer's degeneration
...cognitive functioning, cell loss and overall brain deterioration in an experimental animal model. The study demons... from other types of diabetes. In the study, brain deterioration was not related to the pancreas, which regulates insulin for the body. When pancreatic insulin is de...Social mealtimes boost wellbeing of nursing home residents
... Residents of nursing homes not only face physical deterioration but also loss of independence, privacy, and a familiar environment. These factors lead to high levels of loneliness and depression and a low perceived quality of life. Mealtimes in nursing homes provide an opportunity to integrate physical care with ...Biologic therapies lead evolution of Crohn's treatments
... infection damaging nerve cells and causing mental deterioration which may be fatal, named for a patient first diagnosed with the disease). The evaluation included a physical exam, referral to a neurologist, brain MRI and analysis of cerebral spinal fluid (CSF) and serum for JC virus. An independent expert commi...New biomarkers for improving treatment of spondylarthritis
...he control group; in fact, there was a significant deterioration in patient assessment of pain. But the most noteworthy findings came from the analysis of whether changes in synovial tissue correlated with changes in disease activity between patients who had received effective treatment and those who had not. ...Smoking, diabetes predict different forms of peripheral artery disease
...D. During follow up, patients showed a significant deterioration in ABI and TBI, although some remained stable. Those suffering the steepest declines (the highest 10 percent), with at least a 0.30 decrease in ABI or 0.27 decrease in TBI, were considered to have major PAD progression. Researchers compared risk fa...Free radical cell death switch identified
...time of oxidative stress leads to general cellular deterioration associated with aging and degenerative diseases. How the oxidative-stress signals trigger these profound effects in cells has remained unclear. But Bonni and his research team, including Maria Lehtinen, a graduate student in the HMS program in neuro...Duke University study finds hearing aids are underused
...ips with family and friends, depression and even a deterioration of basic well-being, but only one in five Americans who could benefit from a hearing aid has one and just one-third of those who have hearing aids use them. These are among the key findings of a literature review conducted by the Medical Technolo......is medication that this widely used to prevent the deterioration of bone strength. They found that the universal screen and treatment strategy was only cost-effective for men over the age of 85 (see conference Abstract No. P109). In those patients the cost of gaining each quality-adjusted life year (QALY) was les...