Inflammatory system genes linked to cognitive decline after heart surgery
...nal evidence for a genetic basis for the cognitive deterioration seen after heart surgery. The researchers found that patients with variants in genes for C-reactive protein and P-selectin were less likely to suffer cognitive decline than were patients without the variants. C-reactive protein plays an important r...First clinical trial of gene therapy for childhood blindness
...inal degeneration. This disease causes progressive deterioration in vision, due to an abnormality in a particular gene called RPE65. This defect prevents normal function of the retina, the light-sensitive layer of cells at the back of the eye. This results in severely impaired vision from a very young age and ther...Once-a-year drug reduces fractures from osteoporosis
...zoledronic acid, such as the renal damage and bone deterioration that has been seen at much larger doses in oncology treatments. The HORIZON study showed no such findings at the lower dose required for osteoporosis treatments. The study did observe a small increase in the incidence of atrial fibrillation in pati...Coenzyme Q10 does not improve Parkinson's disease symptoms
...igh doses of CoQ10 (1,200 milligrams) may slow the deterioration associated with Parkinson's disease. Alexander Storch, M.D., of the Technical University of Dresden, Germany, and colleagues conducted a randomized clinical trial of a 300-milligram dose of CoQ10 in 131 patients with Parkinson's disease who did not...New long-term data analyses for Bifeprunox show favorable effects vs. placebo
...lacebo, bifeprunox significantly prolonged time to deterioration over six months. Bifeprunox patients experienced decreases in body weight and body mass index vs. placebo over six months. Bifeprunox patients showed favorable effects on total cholesterol, triglycerides, very low-density lipoprotein and low...Loss of stem cells correlates with premature aging in animal study
... Think of aging as a slow loss of stem cells, a deterioration of pools of cells that reside in each tissue type, says Brown. We accelerated the aging process by wiping out a large fraction of these cells prematurely, in one fell swoop. Essentially, these mice start their young adulthood with two strikes against...'Cars' imaging reveals clues to myelin damage
...ed extensively in laboratory research to study the deterioration of myelin, which insulates nerve fibers and enables them to properly conduct impulses in the spinal cord, brain and peripheral nervous system throughout the body. The findings suggest that LPC causes sheath degradation by allowing an influx of calc...Better mobility keeps seniors healthier
...ility to walk unaided, they tend to suffer further deterioration that can interfere with other daily living activities. As the U.S. population ages, it becomes increasingly important to identify and target interventions for those people who are at risk for further disabilities and illness. In a paper published in ...Where's the beef? Not enough of it is on elders' plates, muscle-metabolism study suggests
...sh, pork, chicken, dairy or nuts may help slow the deterioration of elderly peoples muscles. Reducing the decline in muscle mass among the elderly is crucial to maintaining their health and independence, these researchers say. And they add that consuming adequate protein is essential for making and maintaining ...Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
...ves journals. Prevention of further visual field deterioration is a goal of glaucoma therapy, the authors write as background information in the article. Previous studies reported that lowering intraocular pressure (IOP) slowed the advancement of visual field damage in patients with glaucoma. However, even if th...