Mayo Clinic: Biomarker that may improve quality of life during treatment for colorectal cancer
... Because the variations occur in genes involved in detoxifying oxaliplatin, the researchers hypothesized that the variations could be used as biological markers -- biomarkers -- that would indicate which patients are most susceptible to oxaliplatin's negative side effects. Their results confirmed this. Using gen...Broccoli sprouts, cabbage, ginkgo biloba and garlic: A grocery list for cancer prevention
... has shown that sulforaphane boosts protective and detoxifying reactions in cells, inactivating carcinogens and reactive oxygen intermediates that contribute to the disease by damaging DNA. As in other studies involving the anti-cancer potential of sulforaphane, Dinkova-Kostova's group notes that broccoli sprout...New strides being made in chemoprevention
...ulator of the majority of antioxidant pathways and detoxifying enzymes for environmental pollutants. "The unparalleled potency of CDDO-Im in rats highlights the chemopreventive promise of targeting Nrf2 pathways with triterpenoids, and provides a new direction for drug development," said Dr. Yates. "The trit...Variations in detoxifying genes linked to Lou Gehrig's disease
...d on chromosome 7q21.3, code for the production of detoxifying enzymes involved in the metabolism of a variety of drugs, organophosphate insecticides, such as parathion, diazinon and chlorpyrifos, and nerve gas agents such as sarin. Previous research described a possible twofold increased risk for developing AL...