Sucampo Pharmaceuticals submits supplemental new drug application for Lubiprostone to treat IBS-C
...ation or a change in bowel habits with features of disordered defecation. The supplemental application is based on a clinical study program that included two Phase III, multi-center, double-blinded, randomized, placebo-controlled trials involving 1,171 adults, followed by one long-term, open-label safety and...Dating violence and sexual assault associated with suicide attempts among urban teens
...s included sexual orientation, persistent sadness, disordered eating, feeling unsafe at school, being in a physi...s included sexual orientation, persistent sadness, disordered eating, drug use and gun possession. While our study focused on public high school students in a ...Both alcohol and neighborhood characteristics can affect intimate partner violence
.../cohabiting men, drinking and living in a socially disordered neighborhood both contribute to elevated risk for mutual IPV," said Cunradi. "For married/cohabiting women, except those who are the heaviest drinkers, drinking contributes to elevated risk for mutual IPV, but only in the context of higher neighborh...New study demonstrates that Lubiprostone may improve symptom relief rates in adults with IBS-C
...ation or a change in bowel habits with features of disordered defecation. Lubiprostone is a novel selective chloride channel activator that has been shown to be effective and well-tolerated in a number of well-controlled clinical trials in patients with chronic idiopathic constipation. Lubiprostone is markete...Children from low income families more likely to have sleep problems
..., night terrors, bed wetting, sleep walking, sleep disordered breathing, daytime sleepiness, bedtime resistance, and the time it took their children to fall asleep. The study found children from low income families had 25 percent more incidents of sleeping problems than children from middle class families. ...Gender, ethnic differences may hamper eating disorder diagnosis
...he sufferers don't display the typical symptoms of disordered eating. "We need to think more broadly about who...en hospitalized at least once as a result of their disordered eating, a criteria shared by fewer than one in five Caucasians (13.2 percent), and they reported a l...Water flows like molasses on the nanoscale
...al Review B. In its bulk liquid form, water is a disordered medium that flows very readily. When most substances are compressed into a solid, their density increases. But water is different; when it becomes ice, it becomes less dense. For this reason, many scientists reasoned that when water is compressed (as...New dopamine brain target discovered
...h tells us that people with schizophrenia may have disordered calcium signals, and the major treatments for this disease target the dopamine system. Drs. George and O'Dowd state, "our data links these two pieces of evidence, creating better understanding of the disease and opening the door for a new generation ...Study finds gender differences related to eating and body image
... of the first steps involved in the development of disordered eating, be it anorexia, bulimia or compulsive eating. Our commercial mass media are filled with such external cues. "It is our hope that future studies will be devoted to furthering our understanding of how young people, especially those who are m...UW-Madison researchers clear way to stronger glass
... over time. Conventional glasses are relatively disordered and molecularly unstable because of how they are made. Glass ingredients are melted, then cooled and allowed to harden. As the molten glass cools, Ediger says, "The molecules slow down, then get stuck. The question is, did they get stuck in an organi...BIDMC's Terry Strom, M.D., honored by American Society of Nephrology
... attempting to unravel the mysteries of normal and disordered renal function. This award is in recognition of those who follow in his footsteps and contribute to our understanding of how the kidney functions normally and in disease states." In a career spanning more than 30 years, Strom has made critically im...New info on eating disorders in two Stanford/Packard children's studies
...ll whether young children display the same kind of disordered body image disturbance as older children with eating disorders, who often proclaim themselves "fat" or "disgusting." "Young kids may truly not know why they don't want to eat," said Peebles. "They just don't want to be bigger." As a result, more th...First major study of mammalian 'disorderly' proteins
... folded into specific shapes); or mixed ordered or disordered proteins (MPs), which have both structured and unstructured parts. "This work further illustrates that the disorderliness of IUPs isn't just a curiosity," said Charles Galea, Ph.D., a postdoctoral fellow in Kriwacki's lab. "This characteristic is ...Dieting danger: Female athletes limiting calories more likely to get stress fractures
...ed leg pain were a prior history of the condition, disordered eating and excessive pronation (a rolling inwards)...eased bone mineral density, findings suggestive of disordered eating, which is an umbrella term for common eating disorders as well as any other nutritional defic...JRRD tipsheet: Focus on stroke
.... We designed Experiment 1 to define normal versus disordered swallowing based on the range of scores in a sampl...vide an atmosphere of unconditional acceptance for disordered speech. By bringing animals into the therapy session, the sessions may be more pleasurable and less ...Abnormal glucose metabolism may contribute to chronic nerve disorder
...lycemia [high blood sugar] and the consequences of disordered glucose metabolism." According to the two-hour oral glucose tolerance test, 62 patients (62 percent) with neuropathy had abnormal fasting glucose metabolism, including 24 with undiagnosed diabetes. (This compares with 33 percent of patients of simil...When a child's heart stops, onset time of abnormal rhythms is crucial
Ventricular fibrillation, the life-threatening disordered heart rhythms that may accompany full cardiac arrest, occurs more frequently in children than commonly believed, according to a large national pediatric study. Furthermore, not all ventricular fibrillation (VF) is the same, said study co-investigator...Perfectionist fathers can reinforce tendencies
Perfectionist fathers can reinforce disordered eating among college-age young people already preo...tself was not the issue with students who reported disordered eating behaviors," Miller-Day notes. "Personal perfectionism, reinforced by peer and parental expect......enhance our understanding of development of sleep- disordered breathing and reduce morbidity by awareness of high-risk groups." Of the children included in the study, 55 percent were male, 80 percent were Caucasian, 17 percent were African-American, and 3 percent were biracial or Asian. Habitual snoring was def......event morbidity due to untreated obstructive sleep disordered breathing. Children who snore frequently should be...list to rule out the presence of obstructive sleep disordered breathing. "Now that we know how prevalent snoring is in children this young and that it is more com...