Fifteen-year hunt uncovers gene behind 'pseudothalidomide' syndrome
... properly. As a result, the cell doesn't divide or divides very slowly, and the new cells can end up with too many or too few chromosomes (a problem also seen in cancer cells). In Roberts syndrome, the cells tend to stop growing or die, precluding proper development of the limbs, palate and other structures....Blocking the Odc gene is effective in preventing cancers
... to DFMO, the researchers said. "Each time a cell divides it must make a copy of the genome to transmit it to the new daughter cells, a process that is vulnerable to mistakes that cause mutations," said John Cleveland, Ph.D., a member of the Department of Biochemistry at St. Jude. "Curtailing cell division ...UCI researchers create method for predicting most effective use of cancer-fighting drugs
...s consider a population of cells. Each time a cell divides in this group, there is a small probability that a mutation occurs, generating resistant mutant genes. Approaching the issue mathematically, the researchers pose the following question: Given a certain size of a colony of cells, what is the probabili...New Stanford tool for genetic data analysis may improve cancer treatment
...ease. The tool is at the heart of a new study that divides similar-looking kidney tumors into subtypes depending on which of thousands of genes are turned on or off. The idea behind this and related studies of other types of cancer published over the past five years is that doctors can use the information to...Faults in newly discovered breast stem cells may lead to tumours
...l may be more resistant to chemotherapy because it divides more slowly. So while chemotherapy can eliminate the bulk of cancer cells, the tumour factory itself a breast cancer stem cell may survive months or years later. In the context of international breast cancer research, the discovery of the breast s...Stem cell study seeks to prevent heart failure
...neration A human embryo starts with one cell that divides to become many. Early on, stem cells change, or differentiate, from non-specific precursors into specialized cells that make up organs. Within a layer of the embryo called the mesenchyma, for example, mesenchymal stem cells (MSCs) can go on to become...A bulging midriff roughly doubles women's chances of gallstone surgery
...sured 26 inches or less. Waist to hip ratio, which divides the waist size by hip size, also boosted the risk by around 40% among women with a ratio of 0.86 compared with those whose ratio was 0.70 or less. These results held true even if a woman was not generally overweight, as determined by body mass index...Procedure for irregular heartbeat gives long-lasting relief & improves quality of life
...n, the catheter head pokes through the septum that divides the heart vertically, and enters the left atrium, where ablation takes place. The radio wave heats the targeted areas of tissue, a process called ablation, but spares nearby tissue. The new study was the first ever designed specifically to separate t...Life and death in the USA: New study concludes there are 'Eight Americas'
...to conclude that the health of the American people divides them into 'Eight Americas' based on their race, country of residence, and a few other community characteristics with striking differences between them. For example, in 2001, the life expectancy gap between the 3.4 million high-risk urban black mal......and a procedure known as gastric partitioning that divides the stomach into two parts. Most cases of Wernicke encephalopathy occurred from four to 12 weeks after the surgery, although one case occurred 18 months later. Most patients (25) had vomiting as a risk factor. Many of the patients also had three sy...