From aircraft aerodynamics to improved heart implants
...nts more time to obtain a transplant. "With so few donors available compared to the people who need new hearts the number of people with implants is only going to continue increasing," notes Lagasco. Indeed, cardiovascular disease is the principal cause of death in Europe, claiming around four million live......KPD) as a means of efficiently finding more kidney donors who are a match for patients in need. In the study...ants on 21 out of 22 kidney patients whose willing donors were incompatible by matching them up with other incompatible pairs. Robert Montgomery, M.D., Ph.D.,...Use of kidney paired donation for incompatible donors could expand donor pool
...o most significant barriers to greater use of live donors are blood type incompatibility and human leukocyte...om a pool of blood type or crossmatch incompatible donors and recipients with end-stage renal disease (6 conventional and 4 unconventional KPD transplants) be...Men who smoke heavily may impair sperm, fertility
...sperm function was compared to that of non-smoking donors who served as controls and whose fertilizing capacity had been confirmed. Using a test called the Hemizona Assay developed by Burkman, the researchers cut a zona in half, placing one half with a smoker's sperm and the matching half with cont...Past illegal blood donation in China linked to hepatitis C virus infection
... C virus (HCV) infection rates in blood and plasma donors during the 1980s and early 1990s, and that failure to screen for HCV in transfusion recipients increased their risk of infection as well, according to an article in the November 15 issue of The Journal of Infectious Diseases, now available online. So...Report shows steep rise in support for health charities that don't fund animal tests
...giving. After determining that a sizable number of donors were interested in "cruelty-free" giving, PCRM est...ls. The Seal's stylized rabbit makes it simple for donors to quickly determine if a health charity matches their values. PCRM administers the program on behal...Polymorphism and antibodies associated with highly increased risk of rheumatoid arthritis
... positive foranti-CCP antibodies. All of the blood donors who had anti-CCP antibodies andhave the PTPN22 1858T polymorphism had developed RA an average of two and ahalf years after the blood sample was taken....Stem cell study seeks to prevent heart failure
...stem cells obtained from healthy, unrelated, adult donors (not from a fetus, embryo or animal). Provacel, developed by Osiris Therapeutics, Inc., is not yet an approved or marketed therapy. Blood Bank Model Experts believe that mesenchymal stem cells for many reasons have tremendous potential to become...Stem cells from muscles can repair cartilage
...lso notes that patients could potentially serve as donors to themselves, since the current study used MDSCs from juvenile rats and other studies have shown such transplants to be problematic in adults. She concludes: "Thus, further work is warranted to determine the chondroprogenitor potential of MDSCs in a...Blood safety program in South Africa associated with decline in HIV-1 in blood donations
...al risk for all donations in 2001-2002. All blood donors in the Inland region of the South African National... categories. The prevalence of HIV-1 in first-time donors decreased by 45 percent. Donations from the majority black population declined from 6.6 percent to 4...Livers from non-heart beating donors would boost organ supply
Liver transplants from non-heart beating donors have the potential to increase the supply of organ... patients now on the waiting list as the number of donors declines. In general liver donation rates are poor in the UK (13 per million population compared wit...Legal and ethical questions about stem cell research
...al practice, will it really be possible to promise donors anonymity? "It seems highly likely," says Greely, "that the Food and Drug Administration will want as much information as possible about the donor's health, not only with regard to pathogens that may infect the donated cells but also about diseases ...Hypertension drug may restore cardiovascular function in African Americans
...lved in the oxidative stress, in single cells from donors of various ethnic backgrounds. Using nanosensors 1,000 times smaller than a human hair, the researchers could take real-time measurements of nitric oxide levels before and after nebivolol was administered. This nanomedical approach allowed the resear...Double transplants may offer one solution to short supply of donated kidneys
...went double transplants using organs from deceased donors that had been turned down by other centers because...ted into a single recipient." The mean ages of the donors were 22 months for the pediatric kidneys and 65 years for the adult kidneys. Patient survival in bot...The world health organization launches new stop TB strategy in the Lancet
... commit resources to tuberculosis control, and for donors to provide catalytic financial aid. Indeed, the Bill and Melinda Gates Foundation has already pledged US $900 million by 2015. European governments and funding agencies should follow suit."...Blood center's high-tech help for US's blood shortage
...an effective way of both attaining new whole-blood donors and increasing donations from current participants. Over the measurement period, new donors with e-mail addresses increased by 74%, while those without e-mail addresses grew only 2%. Over a pe...Predicting successful outcomes in living-donor liver transplants
...arkers for the quality of liver regeneration in 22 donors and their recipients in the first 3 months followi...mination and GEC remained significantly altered in donors and improved significantly in recipients during that period, while lidocaine elimination showed no s...ISHLT celebrates 20th anniversary of infant cardiac transplantation
...ne year of age can tolerate heart transplants from donors of different blood groups 1, improving the chances of survival for infant candidates and substantially altering the potential donor pool for each individual. "By expanding the boundaries of therapy for congenital heart disease and stimulating resea...NYAS Conference highlights latest advances in primary immunodeficiencies (SCID)
...Feb. 1, 2006 in JAMA showing how matched unrelated donors provided better engraftment, immune reconstitution and survival for SCID patients undergoing bone marrow transplantation compared to mismatched related donors. Alessando Aiuiti, M.D., Ph.D., San Raffaele Telethon Institute for Gene Therapy, Milan. ...Older donor hearts just as good, University of Alberta study shows
Patients who receive healthy hearts from donors 50 years of age and older appear to fare just as w...rdiac Surgery reviewed the outcomes of using heart donors 50 years of age and older and discovered that there were no differences in ICU or post-operative len...