Tag: "dopamine" at medical news
Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
...a link between the loss of both norepinephrine and dopamine
neurons and the delayed onset of symptoms associat...e. It was originally thought that the loss of only dopamine
neurons triggered symptoms. Dopamine is a neurotransmitter critical for coordinating movement. Res...
ADHD appears to be associated with depressed dopamine activity in the brain
...g methylphenidate (Ritalin), which increases brain dopamine
levels, according to a report in the August issue ... of the JAMA/Archives journals. This suggests that dopamine
dysfunction may be involved with ADHD symptoms and may contribute to substance abuse that often occu...
New perspective on brain function now possible
...r important neurotransmission systems, such as the dopamine
and serotonin systems, until now it has not been p...nes currently available on the market work via the dopamine
system, for example. However, it may well turn out that glutamate receptors are even better drug tar...
In utero exposure to smoking by mother can increase risk of ADHD
... child has either or both of two specific forms of dopamine
pathway genes (DAT and DRD4), and was exposed to cigarette smoking in utero, the risk for having combined type ADHD (many inattention and hyperactive/impulsive symptoms) increased 3 to 9 fold." John H. Krystal, M.D., Editor of Biological Psychiatry...
Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys
generators (dopaminergics) in brain cells has prod...ration and the cardiac frequency through releasing dopamine
in situations of low oxygen level in the blood. After the implantation of the cellular aggregates of...
Exercise may lead to improvement in patients with Parkinson's
...exercise in animal models looked at the effects of dopamine
in motor learning and execution. Parkinson's D...n's Patient might suffer. Given the importance of dopamine
in Parkinson's Disease, the researchers looked at changes in dopamine
levels, among other results. ...
Dopamine-related drugs affect reward-seeking behavior
BOSTON -- Drugs that adjust dopamine
levels in the brain greatly affect how people reac...ne group was given levodopa, a drug that increases dopamine
levels in the brain. Another took haloperidol, a dopamine
receptor blocker. The third was given a pl...
Drugs for Parkinson's disease may ease stroke-related disability
...e to loss of neurons that use the neurotransmitter dopamine
to regulate activity in the putamen. "Earlier attempts to treat stroke patients with neglect with dopamine-like compounds have produced mixed results," says lead author Ayelet Sapir, Ph.D., postdoctoral researcher in neurology. "It's possible, tho...
New treatment possibilities for fatal genetic disease
...theory incorrect. It was previously thought that dopamine
neurons, called D2 neurons, were responsible for the devastating symptoms seen in Huntingtons disease but the Florey researchers have proven that loss of D1 neurons causes many of the fatal diseases disabling symptoms. In Huntingtons disease, the f...
Energy supplement under study for Parkinson's disease
...herapies including the gold standard, a synthetic dopamine
called levodopa and MAO-B inhibitors that forestall breakdown of dopamine
are geared toward treating symptoms. Dopamine, a neurotransmitter critical to movement, is depleted...
Addiction breakthrough may lead to new treatments
...een exposed to drugs, had significantly less brain dopamine
receptors than their more restrained counterparts....e Wellcome Trust, demonstrates that the changes in dopamine
receptors and impulsivity pre-date drug use and do not emerge as a result of prolonged addiction. H...
The influence of the menstrual cycle on the female brain
...s self-administer cocaine (a drug that acts on the dopamine
system) in higher doses after estrogens have been ...on activity in the brain. Dopaminergic neurons use dopamine
as a neurotransmitter/neuromodulator. 2. Structures including the ventral striatum, the anterior c...
New dopamine brain target discovered
...on and Mental health (CAMH), discovered a distinct dopamine
signalling complex in the brain. Composed of two different types of dopamine
receptors, this novel target may have a significant role in understanding and treating schizophrenia...
New research identifies gene important for nicotine's effects on the brain
...t receives nicotine and, therefore, focused on the dopamine
system in the brain. Dopamine is one of a number ...tion and reward processes. Nicotine activates the dopamine
system in the brain as do other drugs of abuse including cocaine and amphetamines. "Our work and ...
Synchronous neuronal firing may underlie Parkinson's disease
...needs to travel through the brain, neurons release dopamine
to transport the signal across the gap, or synapse...nd of protein pump, called a transporter, recycles dopamine
back to the signaling neurons to prepare for the next burst of signal. In studies 10 years ago, Mar...
Stress triggers relapse in meth abuse, OHSU study finds
...also is studying the effects the neurotransmitters dopamine
and acetylcholine have on stress response. "We want to find those areas of the brain that are sensitive to the (2-DG) stressor and that area should be linked to other areas of the brain that cause the animal to push that lever again, to relapse," M...
Dopamine imbalances cause sleep disorders in animal models of Parkinson's disease and schizophrenia
...engineered mice have found that the brain chemical dopamine
plays a critical role in regulating sleep and brain activity associated with dreaming. When dopamine
levels were dramatically reduced, the mice could no longer sleep, the scientists said. When dopamine...
Appetite changes, depression signal impulse control disorders in Parkinson disease
...essive shopping have been linked to treatment with dopamine
agonists in small numbers of patients. It is unkno...rd anti-Parkinson medications, including levodopa, dopamine
agonists, and other drugs. They administered a standard battery of psychiatric tests to identify the...
Leptin has powerful effect on reward center in the brain
... leptin signaling, via its receptor, occurs in the dopamine
neurons in the VTA and that it results in decrease...ivity of these neurons. "Metabolic control over dopamine
neuron function in the VTA is likely to have consequences for a broad range of behaviors and associa...
OREXIGEN reports positive 24-week results for Contrave phase III obesity treatment study
...trave is a proprietary combination of bupropion, a dopamine
and norepinephrine reuptake inhibitor, with one of several different doses of naltrexone, an opioid antagonist used to treat various addictive disorders. The bupropion/naltrexone combination is based on the company's underlying research into the brai...
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