JCI Table of Contents, April 3, 2006
...n the expression of various antioxidant genes, are dramatically more susceptible to death following acute exposure to a bacterial cell wall sugar called LPS and to surgically-induced sepsis. The authors examined post-LPS-treatment lung inflammation in the mice and found that Nrf2-deficient animals had significant...Special education data provide misleading trends of changing autism prevalence
... and sorted in special education settings can vary dramatically from school to school. "Schools nationwide don't adhere to any common diagnostic guidelines when they're sorting kids into these categories," Shattuck explains. "States and individual schools are left to devise criteria. Everyone is using a differen...President's budget proposal cuts critical infectious diseases programs to the bone
...ts will pay significant dividends in the future by dramatically reducing health care costs and improving the quality of life for millions of Americans," Dr. Blaser said. "In addition, as the global leader in infectious diseases research and prevention, the United States will see these benefits translate into worl......r heart and lung transplant patients have improved dramatically in the last 15 years. More than 64 percent of patients who underwent transplantation between 2000 and 2003 survived for at least three years, in comparison to slightly more than 55 percent of individuals operated on between 1988 and 1994. These stat...Minimally invasive approach can work for many thyroid patients
...ave two safe, effective treatment options that can dramatically reduce the size of their neck incisions and speed recovery, researchers say. Options include minimally invasive thyroidectomy, in which surgeons work through an incision about half the size of the norm, and an endoscopic approach, in which video moni...Doctors in training improve skills via virtual patient
...onic stethoscope that doubles as a virtual patient dramatically improved the accuracy of medical residents in identifying heart sounds, according to a study presented today at the American College of Cardiology. Research has revealed an alarmingly low 21 percent accuracy rate among medical residents using a stet...Only four percent of Americans with bladder problems seek medical help
... medical need identified by our study may increase dramatically in the next 30 years as people live longer and older people make up a larger percentage of the population. "Greater public awareness of the causes of OAB and the treatment available - could substantially increase the overall health and quality o...New test to detect rare proteins in blood
...TT method her2/neu positive cancer patients showed dramatically elevated Her2/neu levels (average: 384 ng/ml), while the level in Her2/neu-negative breast cancer patients (19.5 ng/ml) were close to the levels of the healthy control participants (16.6 ng/ml). Using FACTT, nine out of 10 of the Her2/neu positive p...Dramatic changes in US aging highlighted in new census, NIH report
The face of aging in the United States is changing dramatically -- and rapidly, according to a new U.S. Census Bureau report, commissioned by the National Institute on Aging (NIA). Today's older Americans are very different from their predecessors, living longer, having lower rates of disability, achieving higher...Johns Hopkins scientists exploit novel route to reverse enlarged hearts in obese mice
...to mimic the activity of the brain hormone leptin, dramatically reducing the size of the heart muscle. Leptin is a protein hormone made by fat cells that signals the brain to stop eating. Alterations in the leptin-making gene may create leptin deficiency linked to obesity and other defects in weight regulation....Antibody therapy reduces asthma in mice
...after allergen exposure, the allergic response was dramatically prevented, and the severity of asthma-like symptoms was reduced, suggesting that C5aR increases the body's response to asthma-inducing stimuli only in an established allergic environment. In an accompanying commentary, Bart N. Lambrecht from Erasmus ...New anti-drug program shows 'phenomenal' success by focusing on positives
...ol and community communication campaign really can dramatically cut marijuana and alcohol use among young teens. In a study of 32 schools in 16 communities around the country, researchers found that the campaign cut in half the number of students who began using marijuana and alcohol during the two years of the p...Fighting the battle against disease - Leeds researchers take on the world
...lity, relevance and timeliness of our evidence can dramatically alter the approach and results of reaching the poor." Their successful approach to development is based on ten years of public health programme design and implementation experience, ensuring that the interventions are sustainable, affordable and acce...New insights into the link between rheumatoid arthritis and cancer
...ase in the risk for lymphoma. The odds ratio rose dramatically for high RA activity--to a 70-fold increase in lymphoma risk. The researchers also observed increased risks of lymphoma associated with pronounced, irreversible joint damage in the hands, feet, and knees documented in the last year before lymphoma d...Globalization: Children and working parents pay too high a price
...this lack of support for working families not only dramatically affects the world's children, it exacerbates gender and income inequalities. According to Senator Edward Kennedy, this research "builds a powerful case for global action on decent working conditions and basic social support for families as the corner...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
...is colleagues speculate that anabolic steroids can dramatically shorten teenage fuses (not known for length under the best of circumstances) and make young people "pop off" for years, a danger to themselves and to others. Melloni and others researchers also are concerned that drug use during a critical window in...Have targets improved performance in the English NHS?
...ported performance improved in other UK countries, dramatically in Wales and Northern Ireland. This suggests that the naming and shaming policy in England put pressure on the NHS in the other countries, say the authors. But the use of targets results in gaming, they add. For example, extra staff being drafted int...New sensor to provide early warning of oxygen loss to unborn children
..., have devised a new sensor which has the power to dramatically improve the amount of early warning doctors and midwives get of a dangerous situation in the birth process when the unborn child's brain is starved of oxygen - Fetal Hypoxia. The threat of fetal hypoxia carries dangers not only for the child but also...Drug aimed at Huntington's eases chorea, the disease's hallmark feature
...e in Europe and Canada but not the United States dramatically eases one of the most disabling symptoms of Huntingtons disease, involuntary writhing movements known as chorea, according to a study in the Feb. 14 issue of the journal Neurology. The medication, tetrabenazine, is currently being reviewed by the U.S...... explain, women with cardiovascular disease show a dramatically different response from men. "For women, we found no evidence of any change in risk across the normal range, from 70 to 100, but then their risk seems to rise quickly through the impaired range and continues to increase with higher glucose in the dia...